The Metabotropic Purinergic P2Y Receptor Family as Novel Drug Target in Epilepsy
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Metabotropic Purinergic P2Y Receptor Family as Novel Drug Target in Epilepsy
Authors
Keywords
-
Journal
Frontiers in Pharmacology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-03-07
DOI
10.3389/fphar.2018.00193
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Inflammation and Epilepsy: Preclinical Findings and Potential Clinical Translation
- (2018) Gaetano Terrone et al. CURRENT PHARMACEUTICAL DESIGN
- Status epilepticus does not induce acute brain inflammatory response in the Amazon rodent Proechimys, an animal model resistant to epileptogenesis
- (2018) Carla A. Scorza et al. NEUROSCIENCE LETTERS
- Expression and function of the metabotropic purinergic P2Y receptor family in experimental seizure models and patients with drug-refractory epilepsy
- (2017) Mariana Alves et al. EPILEPSIA
- Neuroinflammatory targets and treatments for epilepsy validated in experimental models
- (2017) Eleonora Aronica et al. EPILEPSIA
- Classifications of seizures and epilepsies, where are we? – A brief historical review and update
- (2017) Richard Shek-kwan Chang et al. JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
- The ATP-Gated P2X7 Receptor As a Target for the Treatment of Drug-Resistant Epilepsy
- (2017) Edward Beamer et al. Frontiers in Neuroscience
- Purinergic Signalling: Therapeutic Developments
- (2017) Geoffrey Burnstock Frontiers in Pharmacology
- The role of interleukin-6 signaling in nervous tissue
- (2016) Michelle Rothaug et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The evolution of P2X7 antagonists with a focus on CNS indications
- (2016) Jason C. Rech et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- CADmutations and uridine-responsive epileptic encephalopathy
- (2016) Johannes Koch et al. BRAIN
- Pilocarpine-Induced Status Epilepticus Increases the Sensitivity of P2X7 and P2Y1 Receptors to Nucleotides at Neural Progenitor Cells of the Juvenile Rodent Hippocampus
- (2016) Katalin Rozmer et al. CEREBRAL CORTEX
- Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation
- (2016) Álvaro Sebastián-Serrano et al. HUMAN MOLECULAR GENETICS
- Purinergic signaling in epilepsy
- (2016) François Rassendren et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Nucleotides in neuroregeneration and neuroprotection
- (2016) M. Teresa Miras-Portugal et al. NEUROPHARMACOLOGY
- ATPergic signalling during seizures and epilepsy
- (2016) Tobias Engel et al. NEUROPHARMACOLOGY
- Purinergic mechanisms in neuroinflammation: An update from molecules to behavior
- (2016) Edward Beamer et al. NEUROPHARMACOLOGY
- Adenosinergic signaling in epilepsy
- (2016) Detlev Boison NEUROPHARMACOLOGY
- Variations of ATP and its metabolites in the hippocampus of rats subjected to pilocarpine-induced temporal lobe epilepsy
- (2016) Flávia Doná et al. Purinergic Signalling
- Evidence-Based Guideline: Treatment of Convulsive Status Epilepticus in Children and Adults: Report of the Guideline Committee of the American Epilepsy Society
- (2016) Tracy Glauser et al. Epilepsy Currents
- Epilepsy in pregnancy
- (2016) Michael Owen Kinney et al. BMJ-British Medical Journal
- Epilepsy in pregnancy
- (2016) Michael Owen Kinney et al. BMJ-British Medical Journal
- P2Y Receptors in Synaptic Transmission and Plasticity: Therapeutic Potential in Cognitive Dysfunction
- (2016) Segundo J. Guzman et al. NEURAL PLASTICITY
- Infections, inflammation and epilepsy
- (2015) Annamaria Vezzani et al. ACTA NEUROPATHOLOGICA
- P2X Receptors and Diabetes
- (2015) Carmen Fotino et al. CURRENT MEDICINAL CHEMISTRY
- P2X Receptors in the Cardiovascular System and their Potential as Therapeutic Targets in Disease
- (2015) Vera Ralevic CURRENT MEDICINAL CHEMISTRY
- Enhanced astroglial Ca2+signaling increases excitatory synaptic strength in the epileptic brain
- (2015) Carla Álvarez-Ferradas et al. GLIA
- Altered morphological dynamics of activated microglia after induction of status epilepticus
- (2015) Elena Avignone et al. Journal of Neuroinflammation
- P2Y12receptors: structure and function
- (2015) M. Cattaneo JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Epilepsy: new advances
- (2015) Solomon L Moshé et al. LANCET
- P2X3 receptor antagonist (AF-219) in refractory chronic cough: a randomised, double-blind, placebo-controlled phase 2 study
- (2015) Rayid Abdulqawi et al. LANCET
- Status epilepticus in adults
- (2015) John P Betjemann et al. LANCET NEUROLOGY
- Targeting P2X7 receptor for the treatment of central post-stroke pain in a rodent model
- (2015) Yung-Hui Kuan et al. NEUROBIOLOGY OF DISEASE
- Pannexin-1-mediated ATP release from area CA3 drives mGlu5-dependent neuronal oscillations
- (2015) Jan Lopatář et al. NEUROPHARMACOLOGY
- Modulation of the neuronal network activity by P2X receptors and their involvement in neurological disorders
- (2015) F. Sáez-Orellana et al. PHARMACOLOGICAL RESEARCH
- Supportive or detrimental roles of P2Y receptors in brain pathology?—The two faces of P2Y receptors in stroke and neurodegeneration detected in neural cell and in animal model studies
- (2015) Daniel Förster et al. Purinergic Signalling
- Epileptogenesis
- (2015) Asla Pitkänen et al. Cold Spring Harbor Perspectives in Medicine
- ATP as a multi-target danger signal in the brain
- (2015) Ricardo J. Rodrigues et al. Frontiers in Neuroscience
- Neuropsychological deficits in temporal lobe epilepsy: A comprehensive review
- (2014) Priyanka Rastogi et al. Annals of Indian Academy of Neurology
- ILAE Official Report: A practical clinical definition of epilepsy
- (2014) Robert S. Fisher et al. EPILEPSIA
- P2Y1receptor inhibits GABA transport through a calcium signalling-dependent mechanism in rat cortical astrocytes
- (2014) Pedro F. Jacob et al. GLIA
- P2X and P2Y Receptors—Role in the Pathophysiology of the Nervous System
- (2014) Kamila Puchałowicz et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Expression of Astrocyte-Related Receptors in Cortical Dysplasia With Intractable Epilepsy
- (2014) Sayuri Sukigara et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Neuronal Hyperactivity Recruits Microglial Processes via Neuronal NMDA Receptors and Microglial P2Y12 Receptors after Status Epilepticus
- (2014) U. B. Eyo et al. JOURNAL OF NEUROSCIENCE
- Nucleotide signalling during inflammation
- (2014) Marco Idzko et al. NATURE
- P2X7 receptor: an emerging target in central nervous system diseases
- (2014) Beáta Sperlágh et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Neural regulation of inflammation in the airways and lungs
- (2013) Alice E. McGovern et al. AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL
- Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A
- (2013) Dalia Kasperavičiūtė et al. BRAIN
- Antagonism of purinergic signalling improves recovery from traumatic brain injury
- (2013) Anthony M. Choo et al. BRAIN
- Uridine modulates neuronal activity and inhibits spike-wave discharges of absence epileptic Long Evans and Wistar Albino Glaxo/Rijswijk rats
- (2013) Zsolt Kovács et al. BRAIN RESEARCH BULLETIN
- ATP P2Y1 receptors control cognitive deficits and neurotoxicity but not glial modifications induced by brain ischemia in mice
- (2013) Marta R. S. Carmo et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Experimental Models of Status Epilepticus and Neuronal Injury for Evaluation of Therapeutic Interventions
- (2013) Doodipala Reddy et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Clinical evaluation of the efficacy of the P2X7purinergic receptor antagonist AZD9056 on the signs and symptoms of rheumatoid arthritis in patients with active disease despite treatment with methotrexate or sulphasalazine
- (2012) Edward C Keystone et al. ANNALS OF THE RHEUMATIC DISEASES
- K+depolarization evokes ATP, adenosine and glutamate release from glia in rat hippocampus: a microelectrode biosensor study
- (2012) A Heinrich et al. BRITISH JOURNAL OF PHARMACOLOGY
- Purines, Purinergic Receptors, and Cancer
- (2012) F. Di Virgilio CANCER RESEARCH
- Clinical Use of Clopidogrel
- (2012) Nikolaus Sarafoff et al. CURRENT PHARMACEUTICAL DESIGN
- Progress report on new antiepileptic drugs: A summary of the Eleventh Eilat Conference (EILAT XI)
- (2012) Meir Bialer et al. EPILEPSY RESEARCH
- Neuromodulation by Extracellular ATP and P2X Receptors in the CNS
- (2012) Baljit S. Khakh et al. NEURON
- Activation of P2X7 Promotes Cerebral Edema and Neurological Injury after Traumatic Brain Injury in Mice
- (2012) Donald E. Kimbler et al. PLoS One
- The Stress-Induced Cytokine Interleukin-6 Decreases the Inhibition/Excitation Ratio in the Rat Temporal Cortex via Trans-Signaling
- (2011) Francisco Garcia-Oscos et al. BIOLOGICAL PSYCHIATRY
- Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice
- (2011) Tobias Engel et al. FASEB JOURNAL
- Purinergic signalling: From normal behaviour to pathological brain function
- (2011) Geoffrey Burnstock et al. PROGRESS IN NEUROBIOLOGY
- P2Y nucleotide receptors: promise of therapeutic applications
- (2010) Kenneth A. Jacobson et al. DRUG DISCOVERY TODAY
- P2Y12receptor-mediated integrin-β1 activation regulates microglial process extension induced by ATP
- (2010) Keiko Ohsawa et al. GLIA
- The role of inflammation in epilepsy
- (2010) Annamaria Vezzani et al. Nature Reviews Neurology
- Cortical thickness analysis in temporal lobe epilepsy: Reproducibility and relation to outcome
- (2010) B. C. Bernhardt et al. NEUROLOGY
- Neural KCNQ (Kv7) channels
- (2009) David A Brown et al. BRITISH JOURNAL OF PHARMACOLOGY
- Release of Adenosine and ATP During Ischemia and Epilepsy
- (2009) Nicholas Dale et al. Current Neuropharmacology
- Basic mechanisms of status epilepticus due to infection and inflammation
- (2009) Annamaria Vezzani et al. EPILEPSIA
- Molecular basis of self-sustaining seizures and pharmacoresistance during status epilepticus: The receptor trafficking hypothesis revisited
- (2009) Claude G. Wasterlain et al. EPILEPSIA
- Refractory status epilepticus: A prospective observational study
- (2009) Jan Novy et al. EPILEPSIA
- Increase of intracellular Ca2+by P2Y but not P2X receptors in cultured cortical multipolar neurons of the rat
- (2009) Wolfgang Fischer et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Interleukin-1β enhances nucleotide-induced and α-secretase-dependent amyloid precursor protein processing in rat primary cortical neurons via up-regulation of the P2Y2receptor
- (2009) Qiongman Kong et al. JOURNAL OF NEUROCHEMISTRY
- Key factors in the discovery and development of new antiepileptic drugs
- (2009) Meir Bialer et al. NATURE REVIEWS DRUG DISCOVERY
- Uracil nucleotides: From metabolic intermediates to neuroprotection and neuroinflammation
- (2008) Davide Lecca et al. BIOCHEMICAL PHARMACOLOGY
- Unilateral hippocampal CA3-predominant damage and short latency epileptogenesis after intra-amygdala microinjection of kainic acid in mice
- (2008) Genshin Mouri et al. BRAIN RESEARCH
- GABA release by basket cells onto Purkinje cells, in rat cerebellar slices, is directly controlled by presynaptic purinergic receptors, modulating Ca2+ influx
- (2008) Roberta Donato et al. CELL CALCIUM
- The drug treatment of status epilepticus in Europe: Consensus document from a workshop at the first London Colloquium on Status Epilepticus
- (2008) EPILEPSIA
- P2Y1receptor signaling enhances neuroprotection by astrocytes against oxidative stress via IL-6 release in hippocampal cultures
- (2008) Takumi Fujita et al. GLIA
- P2Y receptor mediated inhibitory modulation of noradrenaline release in response to electrical field stimulation and ischemic conditions in superfused rat hippocampus slices
- (2008) Cecília Csölle et al. JOURNAL OF NEUROCHEMISTRY
- Status Epilepticus Induces a Particular Microglial Activation State Characterized by Enhanced Purinergic Signaling
- (2008) E. Avignone et al. JOURNAL OF NEUROSCIENCE
- Interleukin Converting Enzyme inhibition impairs kindling epileptogenesis in rats by blocking astrocytic IL-1β production
- (2008) Teresa Ravizza et al. NEUROBIOLOGY OF DISEASE
- Purinergic signalling in the nervous system: an overview
- (2008) Maria P. Abbracchio et al. TRENDS IN NEUROSCIENCES
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search