Infections, inflammation and epilepsy

Anti-inflammatory drugs in epilepsy: does it impact epileptogenesis?

(2015) Annamaria Vezzani   Expert Opinion On Drug Safety

Microglia-Dependent Alteration of Glutamatergic Synaptic Transmission and Plasticity in the Hippocampus during Peripheral Inflammation

(2015) K. Riazi et al.   JOURNAL OF NEUROSCIENCE

Neuromodulatory properties of inflammatory cytokines and their impact on neuronal excitability

(2015) Annamaria Vezzani et al.   NEUROPHARMACOLOGY

Virus and Immune-Mediated Encephalitides: Epidemiology, Diagnosis, Treatment, and Prevention

(2015) James F. Bale   PEDIATRIC NEUROLOGY

IL-1β, IL-6 and IL1Ra levels in temporal lobe epilepsy

(2015) Irem Fatma Uludag et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Mitochondria: diversity in the regulation of the NLRP3 inflammasome

(2015) Prajwal Gurung et al.   TRENDS IN MOLECULAR MEDICINE

Toxoplasmosis and Epilepsy — Systematic Review and Meta Analysis

(2015) Edgard B. Ngoungou et al.   PLoS Neglected Tropical Diseases

Paving the Way to Understand Autoantibody-Mediated Epilepsy on the Molecular Level

(2015) Guiscard Seebohm et al.   Frontiers in Neurology

Epilepsies associated with hippocampal sclerosis

(2014) Fernando Cendes et al.   ACTA NEUROPATHOLOGICA

Prognosis and predictors of outcome of refractory generalized convulsive status epilepticus in adults treated in neurointensive care unit

(2014) Sudhindra Vooturi et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Large-scale analysis of viral nucleic acid spectrum in temporal lobe epilepsy biopsies

(2014) Laura Esposito et al.   EPILEPSIA

Complement C5-deficient mice are protected from seizures in experimental cerebral malaria

(2014) Susan C. Buckingham et al.   EPILEPSIA

Neurocysticercosis: A natural human model of epileptogenesis

(2014) Theodore E. Nash et al.   EPILEPSIA

ILAE Official Report: A practical clinical definition of epilepsy

(2014) Robert S. Fisher et al.   EPILEPSIA

A Novel, Noninvasive, Predictive Epilepsy Biomarker with Clinical Potential

(2014) M. Choy et al.   JOURNAL OF NEUROSCIENCE

Clinical symptoms, diagnosis, and treatment of neurocysticercosis

(2014) Hector H Garcia et al.   LANCET NEUROLOGY

Impaired cognitive ability and anxiety-like behavior following acute seizures in the Theiler's virus model of temporal lobe epilepsy

(2014) Anthony D. Umpierre et al.   NEUROBIOLOGY OF DISEASE

Past and Present Definitions of Epileptogenesis and Its Biomarkers

(2014) Asla Pitkänen et al.   Neurotherapeutics

Brain Abscess

(2014) Matthijs C. Brouwer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nodding syndrome since 2012: recent progress, challenges and recommendations for future research

(2014) R. Colebunders et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

Inflammatory Processes, Febrile Seizures, and Subsequent Epileptogenesis

(2014) ManKin Choy et al.   Epilepsy Currents

Status Epilepticus in the Setting of Acute Encephalitis

(2014) Daniel H. Lowenstein et al.   Epilepsy Currents

Exposure to Multiple Parasites Is Associated with the Prevalence of Active Convulsive Epilepsy in Sub-Saharan Africa

(2014) Gathoni Kamuyu et al.   PLoS Neglected Tropical Diseases

Herpes Simplex Encephalitis as a Potential Cause of Anti–N-Methyl-d-Aspartate Receptor Antibody Encephalitis

(2014) Allen DeSena et al.   JAMA Neurology

Anti-NMDAR autoimmune encephalitis

(2013) Kazushi Miya et al.   BRAIN & DEVELOPMENT

Antibodies in Epilepsy

(2013) Cynthia M. Correll   Current Neurology and Neuroscience Reports

Increased excitability and molecular changes in adult rats after a febrile seizure

(2013) Aylin Y. Reid et al.   EPILEPSIA

International consensus classification of hippocampal sclerosis in temporal lobe epilepsy: A Task Force report from the ILAE Commission on Diagnostic Methods

(2013) Ingmar Blümcke et al.   EPILEPSIA

Cyclooxygenase-2 in epilepsy

(2013) Asheebo Rojas et al.   EPILEPSIA

The dual role of TNF-α and its receptors in seizures

(2013) Silvia Balosso et al.   EXPERIMENTAL NEUROLOGY

Opposing actions of hippocampus TNFα receptors on limbic seizure susceptibility

(2013) Marc S. Weinberg et al.   EXPERIMENTAL NEUROLOGY

Autoimmune encephalitis: Recent updates and emerging challenges

(2013) Sudarshini Ramanathan et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Neuroprotective and antiepileptogenic effects of combination of anti-inflammatory drugs in the immature brain

(2013) Young Se Kwon et al.   Journal of Neuroinflammation

Prevalence of active convulsive epilepsy in sub-Saharan Africa and associated risk factors: cross-sectional and case-control studies

(2013) Anthony K Ngugi et al.   LANCET NEUROLOGY

Mitochondrial-derived N-formyl peptides: Novel links between trauma, vascular collapse and sepsis

(2013) C.F. Wenceslau et al.   MEDICAL HYPOTHESES

New avenues for anti-epileptic drug discovery and development

(2013) Wolfgang Löscher et al.   NATURE REVIEWS DRUG DISCOVERY

Pharmacological blockade of IL-1β/IL-1 receptor type 1 axis during epileptogenesis provides neuroprotection in two rat models of temporal lobe epilepsy

(2013) F.M. Noe et al.   NEUROBIOLOGY OF DISEASE

Receptor for Advanced Glycation Endproducts is upregulated in temporal lobe epilepsy and contributes to experimental seizures

(2013) Valentina Iori et al.   NEUROBIOLOGY OF DISEASE

TLR4, ATF-3 and IL8 inflammation mediator expression correlates with seizure frequency in human epileptic brain tissue

(2013) Katharina Pernhorst et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Inflammatory pathways of seizure disorders

(2013) Nicola Marchi et al.   TRENDS IN NEUROSCIENCES

Epilepsy and Neurocysticercosis in Latin America: A Systematic Review and Meta-analysis

(2013) Elisa Bruno et al.   PLoS Neglected Tropical Diseases

Case-control Studies on the Relationship between Onchocerciasis and Epilepsy: Systematic Review and Meta-analysis

(2013) Christoph Kaiser et al.   PLoS Neglected Tropical Diseases

Epileptic Encephalitis: The Role of the Innate and Adaptive Immune System

(2012) Jan Bauer et al.   BRAIN PATHOLOGY

Seizures and encephalitis: Clinical features, management, and potential pathophysiologic mechanisms

(2012) Benedict D. Michael et al.   EPILEPSIA

Human herpesvirus 6 and 7 in febrile status epilepticus: The FEBSTAT study

(2012) Leon G. Epstein et al.   EPILEPSIA

Blood-brain barrier dysfunction, TGFβ signaling, and astrocyte dysfunction in epilepsy

(2012) Uwe Heinemann et al.   GLIA

Autoimmune Encephalitis in Children

(2012) Thaís Armangue et al.   JOURNAL OF CHILD NEUROLOGY

Infiltrating Macrophages Are Key to the Development of Seizures following Virus Infection

(2012) Matthew F. Cusick et al.   JOURNAL OF VIROLOGY

Contributions of astrocytes to epileptogenesis following status epilepticus: Opportunities for preventive therapy?

(2012) M.B. Gibbons et al.   NEUROCHEMISTRY INTERNATIONAL

The role of inflammation in epileptogenesis

(2012) Annamaria Vezzani et al.   NEUROPHARMACOLOGY

Neurocysticercosis in the United States

(2012) Jose A Serpa et al.   Pathogens and Global Health

Neurocysticercosis in sub-Saharan Africa: a review of prevalence, clinical characteristics, diagnosis, and management

(2012) Andrea Sylvia Winkler   Pathogens and Global Health

Toxocariasis and Epilepsy: Systematic Review and Meta-Analysis

(2012) Graziella Quattrocchi et al.   PLoS Neglected Tropical Diseases

Brain inflammation as a biomarker in epilepsy

(2011) Annamaria Vezzani et al.   Biomarkers in Medicine

Activation of toll-like receptor, RAGE and HMGB1 signalling in malformations of cortical development

(2011) E. Zurolo et al.   BRAIN

IL-1 receptor/Toll-like receptor signaling in infection, inflammation, stress and neurodegeneration couples hyperexcitability and seizures

(2011) Annamaria Vezzani et al.   BRAIN BEHAVIOR AND IMMUNITY

Infectious causes of seizures and epilepsy in the developing world

(2011) PRATIBHA SINGHI   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Epilepsy and brain inflammation

(2011) Annamaria Vezzani et al.   EXPERIMENTAL NEUROLOGY

Cytokines and brain excitability

(2011) Michael A. Galic et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Neurotropic viral infections leading to epilepsy: focus on Theiler’s murine encephalomyelitis virus

(2011) Jane E Libbey et al.   Future Virology

Interleukin-1 type 1 receptor/Toll-like receptor signalling in epilepsy: the importance of IL-1beta and high-mobility group box 1

(2011) M. Maroso et al.   JOURNAL OF INTERNAL MEDICINE

Brain Infiltration of Leukocytes Contributes to the Pathophysiology of Temporal Lobe Epilepsy

(2011) M. Zattoni et al.   JOURNAL OF NEUROSCIENCE

Epileptiform Activity Induces Vascular Remodeling and Zonula Occludens 1 Downregulation in Organotypic Hippocampal Cultures: Role of VEGF Signaling Pathways

(2011) M. Morin-Brureau et al.   JOURNAL OF NEUROSCIENCE

Interleukin-6, Produced by Resident Cells of the Central Nervous System and Infiltrating Cells, Contributes to the Development of Seizures following Viral Infection

(2011) J. E. Libbey et al.   JOURNAL OF VIROLOGY

Suppression of synaptic plasticity by cerebrospinal fluid from anti-NMDA receptor encephalitis patients

(2011) Qing Zhang et al.   NEUROBIOLOGY OF DISEASE

Interleukin-1β Biosynthesis Inhibition Reduces Acute Seizures and Drug Resistant Chronic Epileptic Activity in Mice

(2011) Mattia Maroso et al.   Neurotherapeutics

Overexpression of μ-calpain in the anterior temporal neocortex of patients with intractable epilepsy correlates with clinicopathological characteristics

(2011) Zhan-hui Feng et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Faciobrachial dystonic seizures precede Lgi1 antibody limbic encephalitis

(2010) Sarosh R. Irani et al.   ANNALS OF NEUROLOGY

N-methyl-d-aspartate antibody encephalitis: temporal progression of clinical and paraclinical observations in a predominantly non-paraneoplastic disorder of both sexes

(2010) Sarosh R. Irani et al.   BRAIN

Stiff person syndrome-associated autoantibodies to amphiphysin mediate reduced GABAergic inhibition

(2010) Christian Geis et al.   BRAIN

Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan’s syndrome and acquired neuromyotonia

(2010) Sarosh R. Irani et al.   BRAIN

Acute symptomatic seizures-Should we retain the term?

(2010) Simon Shorvon et al.   EPILEPSIA

Presence of human herpes virus 6 DNA exclusively in temporal lobe epilepsy brain tissue of patients with history of encephalitis

(2010) Pitt Niehusmann et al.   EPILEPSIA

Estimation of the burden of active and life-time epilepsy: A meta-analytic approach

(2010) Anthony K. Ngugi et al.   EPILEPSIA

Revised terminology and concepts for organization of seizures and epilepsies: Report of the ILAE Commission on Classification and Terminology, 2005-2009

(2010) Anne T. Berg et al.   EPILEPSIA

Afferent facilitation of corticomotor responses is increased by IgGs of patients with NMDA-receptor antibodies

(2010) Mario Manto et al.   JOURNAL OF NEUROLOGY

Development of Postinfection Epilepsy After Theiler's Virus Infection of C57BL/6 Mice

(2010) Kerry-Ann A. Stewart et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Epileptogenesis Provoked by Prolonged Experimental Febrile Seizures: Mechanisms and Biomarkers

(2010) C. M. Dube et al.   JOURNAL OF NEUROSCIENCE

Role for Complement in the Development of Seizures following Acute Viral Infection

(2010) J. E. Libbey et al.   JOURNAL OF VIROLOGY

Blantyre Malaria Project Epilepsy Study (BMPES) of neurological outcomes in retinopathy-positive paediatric cerebral malaria survivors: a prospective cohort study

(2010) Gretchen L Birbeck et al.   LANCET NEUROLOGY

Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

(2010) Mattia Maroso et al.   NATURE MEDICINE

Inflammation enhances epileptogenesis in the developing rat brain

(2010) Stéphane Auvin et al.   NEUROBIOLOGY OF DISEASE

Prevention or Modification of Epileptogenesis after Brain Insults: Experimental Approaches and Translational Research

(2010) W. Loscher et al.   PHARMACOLOGICAL REVIEWS

Epilepsy after head injury: An overview

(2009) Daniel H. Lowenstein   EPILEPSIA

Meta-analysis of the association between cysticercosis and epilepsy in Africa

(2009) Fabrice Quet et al.   EPILEPSIA

Recommendation for a definition of acute symptomatic seizure

(2009) Ettore Beghi et al.   EPILEPSIA

Innate but not adaptive immune responses contribute to behavioral seizures following viral infection

(2009) Nikki J. Kirkman et al.   EPILEPSIA

Etiology and site of temporal lobe epilepsy influence postictal cytokine release

(2009) Sebastian Bauer et al.   EPILEPSY RESEARCH

Contributions of peripheral inflammation to seizure susceptibility: Cytokines and brain excitability

(2009) Kiarash Riazi et al.   EPILEPSY RESEARCH

Neuropathogenesis of Theiler’s Murine Encephalomyelitis Virus Infection, An Animal Model for Multiple Sclerosis

(2009) Ikuo Tsunoda et al.   Journal of Neuroimmune Pharmacology

Cerebral malaria: why experimental murine models are required to understand the pathogenesis of disease

(2009) J. BRIAN de SOUZA et al.   PARASITOLOGY

Severe Neonatal Parechovirus Infection and Similarity With Enterovirus Infection

(2009) Malgorzata A. Verboon-Maciolek et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Epilepsy in Onchocerciasis Endemic Areas: Systematic Review and Meta-analysis of Population-Based Surveys

(2009) Sébastien D. S. Pion et al.   PLoS Neglected Tropical Diseases

Spectrum of neurological syndromes associated with glutamic acid decarboxylase antibodies: diagnostic clues for this association

(2008) Albert Saiz et al.   BRAIN

Seizures following picornavirus infection

(2008) Jane E. Libbey et al.   EPILEPSIA

Viral encephalitis and epilepsy

(2008) Usha Kant Misra et al.   EPILEPSIA

Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies

(2008) Josep Dalmau et al.   LANCET NEUROLOGY

Neuronal surface antigen antibodies in limbic encephalitis: Clinical-immunologic associations

(2008) F. Graus et al.   NEUROLOGY

Cell and gene therapies in epilepsy – promising avenues or blind alleys?

(2008) Wolfgang Löscher et al.   TRENDS IN NEUROSCIENCES

Innate and adaptive immunity during epileptogenesis and spontaneous seizures: Evidence from experimental models and human temporal lobe epilepsy

(2007) Teresa Ravizza et al.   NEUROBIOLOGY OF DISEASE

Glutamic acid decarboxylase antibodies in idiopathic generalized epilepsy and type 1 diabetes

(2006) Pasquale Striano et al.   ANNALS OF NEUROLOGY