Precision dosing in clinical medicine: present and future

Precision Medicine Is Not Just Genomics: The Right Dose for Every Patient

(2018) Richard W. Peck   Annual Review of Pharmacology and Toxicology

Prediction of olanzapine exposure in individual patients using physiologically based pharmacokinetic modelling and simulation

(2018) Thomas M. Polasek et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Pharmacogenomics of GPCR Drug Targets

(2018) Alexander S. Hauser et al.   CELL

Physiologically Based Pharmacokinetic Modeling to Identify Physiological and Molecular Characteristics Driving Variability in Drug Exposure

(2018) Andrew Rowland et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Physiological Regulation of Drug Metabolism and Transport: Pregnancy, Microbiome, Inflammation, Infection, and Fasting

(2018) Edward T. Morgan et al.   DRUG METABOLISM AND DISPOSITION

Are We Ready to Include Organ-Impaired Patients in Oncology Trials? A Clinical Pharmacology Perspective on Recent Recommendations

(2018) Joanna C. Masters et al.   JOURNAL OF CLINICAL PHARMACOLOGY

A dosing algorithm for metformin based on the relationships between exposure and renal clearance of metformin in patients with varying degrees of kidney function

(2017) Janna K. Duong et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections

(2017) T. Tängdén et al.   INTENSIVE CARE MEDICINE

Role of pharmacokinetic modeling and simulation in precision dosing of anticancer drugs

(2017) Adam S. Darwich et al.   Translational Cancer Research

Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approach

(2016) N Marsousi et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Personalized Drug Dosage – Closing the Loop

(2016) Geoffrey T Tucker   PHARMACEUTICAL RESEARCH

Drug interactions: principles and practice

(2016) Ben Snyder et al.   Australian Prescriber

Modeling and simulation in pediatric drug therapy: Application of pharmacometrics to define the right dose for children

(2015) AA Vinks et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline forCYP2D6andCYP2C19Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors

(2015) JK Hicks et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The right dose for every patient: a key step for precision medicine

(2015) Richard W. Peck   NATURE REVIEWS DRUG DISCOVERY

The effect of pharmacogenetic profiling with a clinical decision support tool on healthcare resource utilization and estimated costs in the elderly exposed to polypharmacy

(2015) D. Brixner et al.   JOURNAL OF MEDICAL ECONOMICS

Impact of Modeling and Simulation: Myth or Fact?

(2014) S R B Allerheiligen   CLINICAL PHARMACOLOGY & THERAPEUTICS

Model-Based Drug Development: A Rational Approach to Efficiently Accelerate Drug Development

(2013) P A Milligan et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Axitinib in Metastatic Renal Cell Carcinoma: Results of a Pharmacokinetic and Pharmacodynamic Analysis

(2013) Brian I. Rini et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA-B Genotype and Abacavir Dosing

(2012) M A Martin et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Perpetrators of pharmacokinetic drug-drug interactions arising from altered cytochrome P450 activity: a criteria-based assessment

(2011) Thomas M. Polasek et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Pharmacogenetics: From Bench to Byte— An Update of Guidelines

(2011) J J Swen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network

(2011) M V Relling et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS