Personalized Drug Dosage – Closing the Loop

Clinical Decision Support Tools: The Evolution of a Revolution

(2016) DR Mould et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Pharmacokinetic Evaluation of a Drug Transporter Cocktail Consisting of Digoxin, Furosemide, Metformin, and Rosuvastatin

(2016) P Stopfer et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Influence of genetic polymorphisms in cytochrome P450 oxidoreductase on the variability in stable warfarin maintenance dose in Han Chinese

(2016) Wu-Tao Zeng et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Physiologically-based pharmacokinetic models: approaches for enabling personalized medicine

(2016) Clara Hartmanshenn et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics

(2016) M Gupta et al.   MOLECULAR PSYCHIATRY

Managing diabetes through the skin

(2016) Richard Guy   Nature Nanotechnology

Cost-effectiveness of pharmacogenetic-guided dosing of warfarin in the United Kingdom and Sweden

(2016) T I Verhoef et al.   PHARMACOGENOMICS JOURNAL

Oral, ultra–long-lasting drug delivery: Application toward malaria elimination goals

(2016) Andrew M. Bellinger et al.   Science Translational Medicine

Interindividual variability of CYP2C19-catalyzed drug metabolism due to differences in gene diplotypes and cytochrome P450 oxidoreductase content

(2015) Y Shirasaka et al.   PHARMACOGENOMICS JOURNAL

Dashboard Systems: Implementing Pharmacometrics from Bench to Bedside

(2014) Diane R. Mould et al.   AAPS Journal

Geneva Cocktail for Cytochrome P450 and P-Glycoprotein Activity Assessment Using Dried Blood Spots

(2014) M Bosilkovska et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Challenges in CYP2D6 Phenotype Assignment from Genotype Data: A Critical Assessment and Call for Standardization

(2014) J. Hicks et al.   CURRENT DRUG METABOLISM

Population pharmacokinetic analysis of circadian rhythms in hepatic CYP3A activity using midazolam

(2014) Dorota Tomalik-Scharte et al.   JOURNAL OF CLINICAL PHARMACOLOGY

A Nanogram Dose of the CYP3A Probe Substrate Midazolam to Evaluate Drug Interactions

(2013) B Halama et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A Pharmacogenetic versus a Clinical Algorithm for Warfarin Dosing

(2013) Stephen E. Kimmel et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Randomized Trial of Genotype-Guided Dosing of Warfarin

(2013) Munir Pirmohamed et al.   NEW ENGLAND JOURNAL OF MEDICINE

An agenda for UK clinical pharmacology: Monitoring drug therapy

(2012) Thierry Buclin et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

A comparison of 4β-hydroxycholesterol : cholesterol and 6β-hydroxycortisol : cortisol as markers of CYP3A4 induction

(2012) Yvonne Mårde Arrhén et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Closed Loop Anesthesia

(2011) Anthony R. Absalom et al.   ANESTHESIA AND ANALGESIA

Physiologically-Based Pharmacokinetics in Drug Development and Regulatory Science

(2011) Malcolm Rowland et al.   Annual Review of Pharmacology and Toxicology

Adherence to Medications: Insights Arising from Studies on the Unreliable Link Between Prescribed and Actual Drug Dosing Histories

(2011) Terrence F. Blaschke et al.   Annual Review of Pharmacology and Toxicology

Target-controlled infusion devices: are we missing much?

(2011) Francois Donati et al.   Canadian Journal of Anesthesia-Journal canadien d anesthesie

Thinking Outside the Pillbox — Medication Adherence as a Priority for Health Care Reform

(2010) David M. Cutler et al.   NEW ENGLAND JOURNAL OF MEDICINE

4β-Hydroxycholesterol as an endogenous marker for CYP3A4/5 activity. Stability and half-life of elimination after induction with rifampicin

(2008) Ulf Diczfalusy et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY