Asymmetric activation mechanism of a homodimeric red light-regulated photoreceptor

The Photoconversion of Phytochrome Includes an Unproductive Shunt Reaction Pathway

(2018) David Buhrke et al.   CHEMPHYSCHEM

Structure-guided design and functional characterization of an artificial red light–regulated guanylate/adenylate cyclase for optogenetic applications

(2018) Stefan Etzl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of a novel signal transducer element intrinsic to class IIIa/b adenylate cyclases and guanylate cyclases

(2017) Miriam Ziegler et al.   FEBS Journal

Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase

(2017) Robert Lindner et al.   JOURNAL OF MOLECULAR BIOLOGY

Role of the nucleotidyl cyclase helical domain in catalytically active dimer formation

(2017) Irene Vercellino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of dimer asymmetry and protomer dynamics in enzyme catalysis

(2017) Tae Hun Kim et al.   SCIENCE

Polder maps: improving OMIT maps by excluding bulk solvent

(2017) Dorothee Liebschner et al.   Acta Crystallographica Section D-Structural Biology

Long-range allosteric signaling in red light–regulated diguanylyl cyclases

(2017) Geoffrey Gourinchas et al.   Science Advances

Photoreceptor crosstalk in shade avoidance

(2016) Donald P Fraser et al.   CURRENT OPINION IN PLANT BIOLOGY

Progress in Understanding the Molecular Basis Underlying Functional Diversification of Cyclic Dinucleotide Turnover Proteins

(2016) Ute Römling et al.   JOURNAL OF BACTERIOLOGY

C-di-GMP Synthesis: Structural Aspects of Evolution, Catalysis and Regulation

(2016) Tilman Schirmer   JOURNAL OF MOLECULAR BIOLOGY

Crystal Structure of Deinococcus Phytochrome in the Photoactivated State Reveals a Cascade of Structural Rearrangements during Photoconversion

(2016) E. Sethe Burgie et al.   STRUCTURE

Status of the crystallography beamlines at PETRA III

(2016) Anja Burkhardt et al.   European Physical Journal Plus

Allosteric effects of chromophore interaction with dimeric near-infrared fluorescent proteins engineered from bacterial phytochromes

(2016) Olesya V. Stepanenko et al.   Scientific Reports

Blue light-induced LOV domain dimerization enhances the affinity of Aureochrome 1a for its target DNA sequence

(2016) Udo Heintz et al.   eLife

Structural photoactivation of a full-length bacterial phytochrome

(2016) A. Bjo rling et al.   Science Advances

Spectral properties of bacteriophytochrome AM1_5894 in the chlorophyll d-containing cyanobacterium Acaryochloris marina

(2016) Patrick C. Loughlin et al.   Scientific Reports

Natural Photoreceptors as a Source of Fluorescent Proteins, Biosensors, and Optogenetic Tools

(2015) Daria M. Shcherbakova et al.   Annual Review of Biochemistry

Light-induced Changes in the Dimerization Interface of Bacteriophytochromes

(2015) Heikki Takala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Light Signaling Mechanism of Two Tandem Bacteriophytochromes

(2015) Xiaojing Yang et al.   STRUCTURE

In crystallooptical spectroscopy (icOS) as a complementary tool on the macromolecular crystallography beamlines of the ESRF

(2015) David von Stetten et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural Details of Light Activation of the LOV2-based Photoswitch PA-Rac1

(2014) Andreas Winkler et al.   ACS Chemical Biology

Phototransformation of the Red Light Sensor Cyanobacterial Phytochrome 2 fromSynechocystisSpecies Depends on Its Tongue Motifs

(2014) Katrin Anders et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyanobacteriochrome SesA Is a Diguanylate Cyclase That Induces Cell Aggregation inThermosynechococcus

(2014) Gen Enomoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FTIR Spectroscopy Revealing Light-Dependent Refolding of the Conserved Tongue Region of Bacteriophytochrome

(2014) Emina A. Stojković et al.   Journal of Physical Chemistry Letters

Hexicon 2: Automated Processing of Hydrogen-Deuterium Exchange Mass Spectrometry Data with Improved Deuteration Distribution Estimation

(2014) Robert Lindner et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Signal amplification and transduction in phytochrome photosensors

(2014) Heikki Takala et al.   NATURE

Illuminating cell signalling with optogenetic tools

(2014) Doug Tischer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Phytochromes: An Atomic Perspective on Photoactivation and Signaling

(2014) E. Sethe Burgie et al.   PLANT CELL

An asymmetric heterodomain interface stabilizes a response regulator–DNA complex

(2014) Anoop Narayanan et al.   Nature Communications

Biological photoreceptors of light-dependent regulatory processes

(2013) G. Ya. Fraikin et al.   BIOCHEMISTRY-MOSCOW

Allosteric Activation of Functionally Asymmetric RAF Kinase Dimers

(2013) Jiancheng Hu et al.   CELL

Nucleotide-induced asymmetry within ATPase activator ring drives  54-RNAP interaction and ATP hydrolysis

(2013) T. A. Sysoeva et al.   GENES & DEVELOPMENT

Structure of the Biliverdin Cofactor in the Pfr State of Bathy and Prototypical Phytochromes

(2013) Johannes Salewski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unusual Spectral Properties of Bacteriophytochrome Agp2 Result from a Deprotonation of the Chromophore in the Red-absorbing Form Pr

(2013) Benjamin Zienicke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the Cyanobacterial Phytochrome 2 Photosensor Implies a Tryptophan Switch for Phytochrome Signaling

(2013) Katrin Anders et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger

(2013) U. Romling et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

A ternary AppA–PpsR–DNA complex mediates light regulation of photosynthesis-related gene expression

(2013) Andreas Winkler et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Directed dimerization: anin vivoexpression system for functional studies of type II phytochromes

(2013) Peng Liu et al.   PLANT JOURNAL

Structure and Signaling Mechanism of a Zinc-Sensory Diguanylate Cyclase

(2013) Franziska Zähringer et al.   STRUCTURE

An Asymmetry-to-Symmetry Switch in Signal Transmission by the Histidine Kinase Receptor for TMAO

(2012) Jason O. Moore et al.   STRUCTURE

Structure-guided Engineering Enhances a Phytochrome-based Infrared Fluorescent Protein

(2011) Michele E. Auldridge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Temperature-scan cryocrystallography reveals reaction intermediates in bacteriophytochrome

(2011) Xiaojing Yang et al.   NATURE

Light helps bacteria make important lifestyle decisions

(2011) Mark Gomelsky et al.   TRENDS IN MICROBIOLOGY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural Basis for Negative Cooperativity in Growth Factor Binding to an EGF Receptor

(2010) Diego Alvarado et al.   CELL

Proton-transfer and hydrogen-bond interactions determine fluorescence quantum yield and photochemical efficiency of bacteriophytochrome

(2010) K. C. Toh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Monitoring of diguanylate cyclase activity and of cyclic-di-GMP biosynthesis by whole-cell assays suitable for high-throughput screening of biofilm inhibitors

(2009) Davide Antoniani et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol

(2009) Huanting Liu et al.   BMC BIOTECHNOLOGY

Determinants for the Activation and Autoinhibition of the Diguanylate Cyclase Response Regulator WspR

(2009) Nabanita De et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural and mechanistic determinants of c-di-GMP signalling

(2009) Tilman Schirmer et al.   NATURE REVIEWS MICROBIOLOGY

Obligate Heterodimerization of Arabidopsis Phytochromes C and E and Interaction with the PIF3 Basic Helix-Loop-Helix Transcription Factor

(2009) T. Clack et al.   PLANT CELL

Conformational differences between the Pfr and Pr states in Pseudomonas aeruginosa bacteriophytochrome

(2009) X. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrafast excited-state isomerization in phytochrome revealed by femtosecond stimulated Raman spectroscopy

(2009) Jyotishman Dasgupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Analysis of the GGDEF-EAL Domain-Containing c-di-GMP Receptor FimX

(2009) Marcos V.A.S. Navarro et al.   STRUCTURE

Mutational Analysis ofDeinococcus radioduransBacteriophytochrome Reveals Key Amino Acids Necessary for the Photochromicity and Proton Exchange Cycle of Phytochromes

(2008) Jeremiah R. Wagner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phylogenetic relationships of B-related phytochromes in the Brassicaceae: Redundancy and the persistence of phytochrome D

(2008) Sarah Mathews et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

Beyond polymer polarity: how the cytoskeleton builds a polarized cell

(2008) Rong Li et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The structure of a complete phytochrome sensory module in the Pr ground state

(2008) L.-O. Essen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation-Independent Regulation of the Diguanylate Cyclase WspR

(2008) Nabanita De et al.   PLOS BIOLOGY