Trans -acting translational regulatory RNA binding proteins

Heterogeneous Ribosomes Preferentially Translate Distinct Subpools of mRNAs Genome-wide

(2017) Zhen Shi et al.   MOLECULAR CELL

Polypyrimidine tract-binding protein (PTB) and PTB-associated splicing factor in CVB3 infection: an ITAF for an ITAF

(2017) Pratik Dave et al.   NUCLEIC ACIDS RESEARCH

Viral and cellular mRNA-specific activators harness PABP and eIF4G to promote translation initiation downstream of cap binding

(2017) Richard W. P. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation Mechanisms of Viral IRES-Driven Translation

(2017) Kuo-Ming Lee et al.   TRENDS IN MICROBIOLOGY

Translational reprogramming in tumour cells can generate oncoselectivity in viral therapies

(2017) Eneko Villanueva et al.   Nature Communications

Highly accessible AU-rich regions in 3’ untranslated regions are hotspots for binding of regulatory factors

(2017) Mireya Plass et al.   PLoS Computational Biology

LARP1 functions as a molecular switch for mTORC1-mediated translation of an essential class of mRNAs

(2017) Sungki Hong et al.   eLife

La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs

(2017) Roni M Lahr et al.   eLife

Comprehensive Identification of mRNA-Binding Proteins of Leishmania donovani by Interactome Capture

(2017) Devki Nandan et al.   PLoS One

UNR/CSDE1 Drives a Post-transcriptional Program to Promote Melanoma Invasion and Metastasis

(2016) Laurence Wurth et al.   CANCER CELL

Upstream ORFs are prevalent translational repressors in vertebrates

(2016) Timothy G Johnstone et al.   EMBO JOURNAL

High-Resolution Mapping of RNA-Binding Regions in the Nuclear Proteome of Embryonic Stem Cells

(2016) Chongsheng He et al.   MOLECULAR CELL

Comprehensive Identification of RNA-Binding Domains in Human Cells

(2016) Alfredo Castello et al.   MOLECULAR CELL

Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)

(2016) Eric L Van Nostrand et al.   NATURE METHODS

PABP enhances release factor recruitment and stop codon recognition during translation termination

(2016) Alexandr Ivanov et al.   NUCLEIC ACIDS RESEARCH

Energy landscapes of a mechanical prion and their implications for the molecular mechanism of long-term memory

(2016) Mingchen Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Studies on human eRF3-PABP interaction reveal the influence of eRF3a N-terminal glycin repeat on eRF3-PABP binding affinity and the lower affinity of eRF3a 12-GGC allele involved in cancer susceptibility

(2016) Soumaya Jerbi et al.   RNA Biology

Quantifying RNA binding sites transcriptome-wide using DO-RIP-seq

(2016) Cindo O. Nicholson et al.   RNA

Translational control by 5'-untranslated regions of eukaryotic mRNAs

(2016) A. G. Hinnebusch et al.   SCIENCE

Systematic discovery of cap-independent translation sequences in human and viral genomes

(2016) Shira Weingarten-Gabbay et al.   SCIENCE

Global changes of the RNA-bound proteome during the maternal-to-zygotic transition in Drosophila

(2016) Vasiliy O. Sysoev et al.   Nature Communications

Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish

(2016) Guo-Liang Chew et al.   Nature Communications

Advances in the characterization of RNA-binding proteins

(2016) Domenica Marchese et al.   Wiley Interdisciplinary Reviews-RNA

CPEB4 is regulated during cell cycle by ERK2/Cdk1-mediated phosphorylation and its assembly into liquid-like droplets

(2016) Jordina Guillén-Boixet et al.   eLife

The RNA-binding protein repertoire of Arabidopsis thaliana

(2016) Claudius Marondedze et al.   Scientific Reports

Amyloidogenic Oligomerization Transforms Drosophila Orb2 from a Translation Repressor to an Activator

(2015) Mohammed Repon Khan et al.   CELL

Pausing on Polyribosomes: Make Way for Elongation in Translational Control

(2015) Joel D. Richter et al.   CELL

RCAD/Ufl1, a Ufm1 E3 ligase, is essential for hematopoietic stem cell function and murine hematopoiesis

(2015) M Zhang et al.   CELL DEATH AND DIFFERENTIATION

Extensive cross-regulation of post-transcriptional regulatory networks inDrosophila

(2015) Marcus H. Stoiber et al.   GENOME RESEARCH

La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1)

(2015) Bruno D. Fonseca et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rotavirus NSP3 Is a Translational Surrogate of the Poly(A) Binding Protein-Poly(A) Complex

(2015) Matthieu Gratia et al.   JOURNAL OF VIROLOGY

Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry

(2015) Fan Liu et al.   NATURE METHODS

Protein-RNA networks revealed through covalent RNA marks

(2015) Christopher P Lapointe et al.   NATURE METHODS

Human polypyrimidine tract-binding protein interacts with mitochondrial tRNAThrin the cytosol

(2015) Aline Marnef et al.   NUCLEIC ACIDS RESEARCH

The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer

(2015) Thomas G. Hopkins et al.   NUCLEIC ACIDS RESEARCH

The La-related protein 1-specific domain repurposes HEAT-like repeats to directly bind a 5′TOP sequence

(2015) Roni M. Lahr et al.   NUCLEIC ACIDS RESEARCH

A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation

(2015) A. Minajigi et al.   SCIENCE

Probing RNA–protein networks: biochemistry meets genomics

(2015) Zachary T. Campbell et al.   TRENDS IN BIOCHEMICAL SCIENCES

The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs

(2015) Benedikt M. Beckmann et al.   Nature Communications

SUMOylation Is an Inhibitory Constraint that Regulates the Prion-like Aggregation and Activity of CPEB3

(2015) Bettina Drisaldi et al.   Cell Reports

The Scanning Mechanism of Eukaryotic Translation Initiation

(2014) Alan G. Hinnebusch   Annual Review of Biochemistry

Cytoplasmic Polyadenylation Element Binding Proteins in Development, Health, and Disease

(2014) Maria Ivshina et al.   Annual Review of Cell and Developmental Biology

Poly(A)-binding proteins are required for diverse biological processes in metazoans

(2014) Richard W.P. Smith et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

A Dual Program for Translation Regulation in Cellular Proliferation and Differentiation

(2014) Hila Gingold et al.   CELL

RACK1 Controls IRES-Mediated Translation of Viruses

(2014) Karim Majzoub et al.   CELL

Ribonomic approaches to study the RNA-binding proteome

(2014) Camilla Faoro et al.   FEBS LETTERS

A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins

(2014) T. Afroz et al.   GENES & DEVELOPMENT

Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation

(2014) J. Tcherkezian et al.   GENES & DEVELOPMENT

The expression of CPEB proteins is sequentially regulated during zebrafish oogenesis and embryogenesis

(2014) Marcia L. O'Connell et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

RNA regulons in Hox 5′ UTRs confer ribosome specificity to gene regulation

(2014) Shifeng Xue et al.   NATURE

Structural basis for the assembly of the Sxl–Unr translation regulatory complex

(2014) Janosch Hennig et al.   NATURE

Photo-cross-linking and high-resolution mass spectrometry for assignment of RNA-binding sites in RNA-binding proteins

(2014) Katharina Kramer et al.   NATURE METHODS

A census of human RNA-binding proteins

(2014) Stefanie Gerstberger et al.   NATURE REVIEWS GENETICS

The organization of RNA contacts by PTB for regulation ofFASsplicing

(2014) Ian Mickleburgh et al.   NUCLEIC ACIDS RESEARCH

LARP1 post-transcriptionally regulates mTOR and contributes to cancer progression

(2014) M Mura et al.   ONCOGENE

Reassessment of the Role of TSC, mTORC1 and MicroRNAs in Amino Acids-Meditated Translational Control of TOP mRNAs

(2014) Ilona Patursky-Polischuk et al.   PLoS One

Verification of gene expression profiles for colorectal cancer using 12 internet public microarray datasets

(2014) Yu-Tien Chang   WORLD JOURNAL OF GASTROENTEROLOGY

Involvement of polypyrimidine tract-binding protein (PTBP1) in maintaining breast cancer cell growth and malignant properties

(2014) X He et al.   Oncogenesis

The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation

(2013) Gabriel Leprivier et al.   CELL

Remodelling of a polypyrimidine tract-binding protein complex during apoptosis activates cellular IRESs

(2013) H A King et al.   CELL DEATH AND DIFFERENTIATION

The eIF2α kinases: their structures and functions

(2013) Neysan Donnelly et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

LARP1 specifically recognizes the 3′ terminus of poly(A) mRNA

(2013) Kazuma Aoki et al.   FEBS LETTERS

LARP1 predict the prognosis for early-stage and AFP-normal hepatocellular carcinoma

(2013) Chan Xie et al.   Journal of Translational Medicine

A role for eukaryotic initiation factor 4B overexpression in the pathogenesis of diffuse large B-cell lymphoma

(2013) E Horvilleur et al.   LEUKEMIA

iCLIP: Protein–RNA interactions at nucleotide resolution

(2013) Ina Huppertz et al.   METHODS

Structures of the human and Drosophila 80S ribosome

(2013) Andreas M. Anger et al.   NATURE

System-wide identification of RNA-binding proteins by interactome capture

(2013) Alfredo Castello et al.   Nature Protocols

How cells get the message: dynamic assembly and function of mRNA–protein complexes

(2013) Michaela Müller-McNicoll et al.   NATURE REVIEWS GENETICS

Characterization of prion-like conformational changes of the neuronal isoform of Aplysia CPEB

(2013) Bindu L Raveendra et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The RNA-binding protein repertoire of embryonic stem cells

(2013) S Chul Kwon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

uORFdb—a comprehensive literature database on eukaryotic uORF biology

(2013) Klaus Wethmar et al.   NUCLEIC ACIDS RESEARCH

microRNAs and RNA-binding proteins

(2013) Silvia Anna Ciafrè et al.   RNA Biology

RNA-binding proteins in Mendelian disease

(2013) Alfredo Castello et al.   TRENDS IN GENETICS

The CPEB-family of proteins, translational control in senescence and cancer

(2012) Gonzalo Fernández-Miranda et al.   AGEING RESEARCH REVIEWS

The role of mammalian poly(A)-binding proteins in co-ordinating mRNA turnover

(2012) Matthew Brook et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Critical Role of Amyloid-like Oligomers of Drosophila Orb2 in the Persistence of Memory

(2012) Amitabha Majumdar et al.   CELL

Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins

(2012) Alfredo Castello et al.   CELL

The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts

(2012) Alexander G. Baltz et al.   MOLECULAR CELL

Protein–RNA interactions: new genomic technologies and perspectives

(2012) Julian König et al.   NATURE REVIEWS GENETICS

Global analysis of yeast mRNPs

(2012) Sarah F Mitchell et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A ribosome-specialized translation initiation pathway is required for cap-dependent translation of vesicular stomatitis virus mRNAs

(2012) A. S.-Y. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Possible Involvement of Nemo-like Kinase 1 inXenopusOocyte Maturation As a Kinase Responsible for Pumilio1, Pumilio2, and CPEB Phosphorylation

(2011) Ryoma Ota et al.   BIOCHEMISTRY

PABP Interacting Protein 2A (PAIP2A) Regulates Specific Key Proteins During Spermiogenesis in the Mouse1

(2011) Geraldine Delbes et al.   BIOLOGY OF REPRODUCTION

Neuralized1 Activates CPEB3: A Function for Nonproteolytic Ubiquitin in Synaptic Plasticity and Memory Storage

(2011) Elias Pavlopoulos et al.   CELL

Ribosome-Mediated Specificity in Hox mRNA Translation and Vertebrate Tissue Patterning

(2011) Nadya Kondrashov et al.   CELL

Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes

(2011) Nicholas T. Ingolia et al.   CELL

GGCn polymorphism of eRF3a/GSPT1 gene and breast cancer susceptibility

(2011) Mahboobe Miri et al.   MEDICAL ONCOLOGY

Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data

(2011) Chaolin Zhang et al.   NATURE BIOTECHNOLOGY

Key contribution of CPEB4-mediated translational control to cancer progression

(2011) Elena Ortiz-Zapater et al.   NATURE MEDICINE

Protein-only mechanism induces self-perpetuating changes in the activity of neuronal Aplysia cytoplasmic polyadenylation element binding protein (CPEB)

(2011) S. U. Heinrich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of picornaviral IRESs by PTB shows differential dependence on each PTB RNA-binding domain

(2011) P. Kafasla et al.   RNA

Gene regulation by RNA binding proteins and microRNAs in angiogenesis

(2011) Sung-Hee Chang et al.   TRENDS IN MOLECULAR MEDICINE

The role of IREStrans-acting factors in regulating translation initiation

(2010) Helen A. King et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP

(2010) Markus Hafner et al.   CELL

Meiosis requires a translational positive loop where CPEB1 ensues its replacement by CPEB4

(2010) Ana Igea et al.   EMBO JOURNAL

Both Transcriptional Regulation and Translational Control of ATF4 Are Central to the Integrated Stress Response

(2010) Souvik Dey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The poly(A)-binding protein partner Paip2a controls translation during late spermiogenesis in mice

(2010) Akiko Yanagiya et al.   JOURNAL OF CLINICAL INVESTIGATION

Translational Regulation of Gene Expression during Conditions of Cell Stress

(2010) Keith A. Spriggs et al.   MOLECULAR CELL

Mitotic cell-cycle progression is regulated by CPEB1 and CPEB4-dependent translational control

(2010) Isabel Novoa et al.   NATURE CELL BIOLOGY

iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution

(2010) Julian König et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The RNA binding protein Larp1 regulates cell division, apoptosis and cell migration

(2010) C. Burrows et al.   NUCLEIC ACIDS RESEARCH

Structure-based prediction of RNA-binding domains and RNA-binding sites and application to structural genomics targets

(2010) H. Zhao et al.   NUCLEIC ACIDS RESEARCH

Identification of novel ribonucleo-protein complexes from the brain-specific snoRNA MBII-52

(2010) Y. Soeno et al.   RNA

Pre-mRNA 3′-end processing complex assembly and function

(2010) Serena Chan et al.   Wiley Interdisciplinary Reviews-RNA

HITS-CLIP: panoramic views of protein-RNA regulation in living cells

(2010) Robert B. Darnell   Wiley Interdisciplinary Reviews-RNA

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Drosophila Larp associates with poly(A)-binding protein and is required for male fertility and syncytial embryo development

(2009) Sarah P. Blagden et al.   DEVELOPMENTAL BIOLOGY

RPS25 is essential for translation initiation by the Dicistroviridae and hepatitis C viral IRESs

(2009) D. M. Landry et al.   GENES & DEVELOPMENT

Poly(A)-binding protein binds to the non-polyadenylated 3' untranslated region of dengue virus and modulates translation efficiency

(2009) C. Polacek et al.   JOURNAL OF GENERAL VIROLOGY

Genome-wide Analysis of PTB-RNA Interactions Reveals a Strategy Used by the General Splicing Repressor to Modulate Exon Inclusion or Skipping

(2009) Yuanchao Xue et al.   MOLECULAR CELL

Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins

(2009) Debashish Ray et al.   NATURE BIOTECHNOLOGY

A comprehensive analysis of the La-motif protein superfamily

(2009) C. Bousquet-Antonelli et al.   RNA

Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein

(2008) Kirsty Sawicka et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

A Combinatorial Code for CPE-Mediated Translational Control

(2008) Maria Piqué et al.   CELL

RNA recognition motifs: boring? Not quite

(2008) Antoine Cléry et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structure and function of KH domains

(2008) Roberto Valverde et al.   FEBS Journal

Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP

(2008) Hironori Kawahara et al.   JOURNAL OF CELL BIOLOGY

Poly(A)-Binding Protein-Interacting Protein 1 Binds to Eukaryotic Translation Initiation Factor 3 To Stimulate Translation

(2008) Y. Martineau et al.   MOLECULAR AND CELLULAR BIOLOGY

MicroRNA-10a Binds the 5′UTR of Ribosomal Protein mRNAs and Enhances Their Translation

(2008) Ulf Andersson Ørom et al.   MOLECULAR CELL

A deadenylation negative feedback mechanism governs meiotic metaphase arrest

(2008) Eulàlia Belloc et al.   NATURE

HITS-CLIP yields genome-wide insights into brain alternative RNA processing

(2008) Donny D. Licatalosi et al.   NATURE

Stem cell transcriptome profiling via massive-scale mRNA sequencing

(2008) Nicole Cloonan et al.   NATURE METHODS

Sustained CPEB-Dependent Local Protein Synthesis Is Required to Stabilize Synaptic Growth for Persistence of Long-Term Facilitation in Aplysia

(2008) Maria Concetta Miniaci et al.   NEURON

Proximity of the poly(A)-binding protein to a premature termination codon inhibits mammalian nonsense-mediated mRNA decay

(2008) A. L. Silva et al.   RNA

All translation elongation factors and the e, f, and h subunits of translation initiation factor 3 are encoded by 5'-terminal oligopyrimidine (TOP) mRNAs

(2008) V. Iadevaia et al.   RNA