A role for eukaryotic initiation factor 4B overexpression in the pathogenesis of diffuse large B-cell lymphoma

A phase I/II trial to evaluate the safety, feasibility and activity of salvage therapy consisting of the mTOR inhibitor Temsirolimus added to standard therapy of Rituximab and DHAP for the treatment of patients with relapsed or refractory diffuse large cell B-Cell lymphoma – the STORM trial

(2013) Mathias Witzens-Harig et al.   BMC CANCER

RNA Binding Protein/RNA Element Interactions and the Control of Translation

(2012) Xavier Pichon et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Activity and complexes of mTOR in diffuse large B-cell lymphomas—a tissue microarray study

(2012) Anna Sebestyén et al.   MODERN PATHOLOGY

A unifying model for mTORC1-mediated regulation of mRNA translation

(2012) Carson C. Thoreen et al.   NATURE

The translational landscape of mTOR signalling steers cancer initiation and metastasis

(2012) Andrew C. Hsieh et al.   NATURE

Depletion of eIF4G from yeast cells narrows the range of translational efficiencies genome-wide

(2011) Eun-Hee Park et al.   BMC GENOMICS

Differential Role of BCL2 in Molecular Subtypes of Diffuse Large B-cell Lymphoma

(2011) K. Dunleavy et al.   CLINICAL CANCER RESEARCH

New Strategies in Diffuse Large B-cell Lymphoma: Translating Findings from Gene Expression Analyses into Clinical Practice

(2011) J. W. Friedberg   CLINICAL CANCER RESEARCH

The biological and therapeutic relevance of mRNA translation in cancer

(2011) Sarah P. Blagden et al.   Nature Reviews Clinical Oncology

mRNA helicases: the tacticians of translational control

(2011) Armen Parsyan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Gene Expression Signature of Acquired Chemoresistance to Cisplatin and Fluorouracil Combination Chemotherapy in Gastric Cancer Patients

(2011) Hark Kyun Kim et al.   PLoS One

Computing the Partition Function for Kinetically Trapped RNA Secondary Structures

(2011) William A. Lorenz et al.   PLoS One

DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors

(2011) Y. Jiao et al.   SCIENCE

The role of Bcl-2 family proteins in chronic lymphocytic leukaemia

(2010) Andrea G.S. Buggins et al.   LEUKEMIA RESEARCH

Control of Cell Survival and Proliferation by Mammalian Eukaryotic Initiation Factor 4B

(2010) D. Shahbazian et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

(2009) Nahum Sonenberg et al.   CELL

Bringing DNA Repair in Tumors into Focus

(2009) C. J. Lord et al.   CLINICAL CANCER RESEARCH

p73α isoforms drive opposite transcriptional and post-transcriptional regulation of MYCN expression in neuroblastoma cells

(2008) Emilie Horvilleur et al.   NUCLEIC ACIDS RESEARCH