LARP1 post-transcriptionally regulates mTOR and contributes to cancer progression

Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation

(2014) J. Tcherkezian et al.   GENES & DEVELOPMENT

The La antigen is over-expressed in lung cancer and is a selective dead cancer cell target for radioimmunotherapy using the La-specific antibody APOMAB®

(2014) Alexander H Staudacher et al.   EJNMMI Research

Signaling pathways that control mRNA turnover

(2013) Roopa Thapar et al.   CELLULAR SIGNALLING

LARP1 specifically recognizes the 3′ terminus of poly(A) mRNA

(2013) Kazuma Aoki et al.   FEBS LETTERS

LARP1 predict the prognosis for early-stage and AFP-normal hepatocellular carcinoma

(2013) Chan Xie et al.   Journal of Translational Medicine

Online Survival Analysis Software to Assess the Prognostic Value of Biomarkers Using Transcriptomic Data in Non-Small-Cell Lung Cancer

(2013) Balázs Győrffy et al.   PLoS One

RNA sequencing of cancer reveals novel splicing alterations

(2013) Jeyanthy Eswaran et al.   Scientific Reports

XRN4 and LARP1 Are Required for a Heat-Triggered mRNA Decay Pathway Involved in Plant Acclimation and Survival during Thermal Stress

(2013) Rémy Merret et al.   Cell Reports

mTOR inhibitors in cancer therapy

(2012) Yekaterina Y. Zaytseva et al.   CANCER LETTERS

Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins

(2012) Alfredo Castello et al.   CELL

mTOR as a Molecular Target in HPV-Associated Oral and Cervical Squamous Carcinomas

(2012) A. A. Molinolo et al.   CLINICAL CANCER RESEARCH

Versatility of RNA-Binding Proteins in Cancer

(2012) Laurence Wurth   COMPARATIVE AND FUNCTIONAL GENOMICS

The regulation of mRNA stability in mammalian cells: 2.0

(2012) Xiangyue Wu et al.   GENE

LARP7 is a potential tumor suppressor gene in gastric cancer

(2012) Yulan Cheng et al.   LABORATORY INVESTIGATION

miRNA-100 Inhibits Human Bladder Urothelial Carcinogenesis by Directly Targeting mTOR

(2012) C. Xu et al.   MOLECULAR CANCER THERAPEUTICS

The translational landscape of mTOR signalling steers cancer initiation and metastasis

(2012) Andrew C. Hsieh et al.   NATURE

The role of the 3' untranslated region in post-transcriptional regulation of protein expression in mammalian cells.

(2012) Eva Matoulkova et al.   RNA Biology

Activation of mammalian target of rapamycin pathway confers adverse outcome in nonsmall cell lung carcinoma

(2011) Dan Liu et al.   CANCER

Integrative Regulatory Mapping Indicates that the RNA-Binding Protein HuR Couples Pre-mRNA Processing and mRNA Stability

(2011) Neelanjan Mukherjee et al.   MOLECULAR CELL

The biological and therapeutic relevance of mRNA translation in cancer

(2011) Sarah P. Blagden et al.   Nature Reviews Clinical Oncology

Phosphoproteomic Analysis Identifies Grb10 as an mTORC1 Substrate That Negatively Regulates Insulin Signaling

(2011) Y. Yu et al.   SCIENCE

The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling

(2011) P. P. Hsu et al.   SCIENCE

p53 regulates Ki-67 promoter activity through p53- and Sp1-dependent manner in HeLa cells

(2011) Mei-Juan Wang et al.   TUMOR BIOLOGY

Guidelines for the welfare and use of animals in cancer research

(2010) P Workman et al.   BRITISH JOURNAL OF CANCER

Overexpression of the Mammalian Target of Rapamycin: A Novel Biomarker for Poor Survival in Resected Early Stage Non-small Cell Lung Cancer

(2010) Tony Dhillon et al.   Journal of Thoracic Oncology

mRNA Degradation Plays a Significant Role in the Program of Gene Expression Regulated by Phosphatidylinositol 3-Kinase Signaling

(2010) J. R. Graham et al.   MOLECULAR AND CELLULAR BIOLOGY

HuR Uses AUF1 as a Cofactor To Promote p16INK4 mRNA Decay

(2010) N. Chang et al.   MOLECULAR AND CELLULAR BIOLOGY

A Link between mir-100 and FRAP1/mTOR in Clear Cell Ovarian Cancer

(2010) Ankur K. Nagaraja et al.   MOLECULAR ENDOCRINOLOGY

The RNA binding protein Larp1 regulates cell division, apoptosis and cell migration

(2010) C. Burrows et al.   NUCLEIC ACIDS RESEARCH

The RNA-binding protein La contributes to cell proliferation and CCND1 expression

(2010) G Sommer et al.   ONCOGENE

Drosophila Larp associates with poly(A)-binding protein and is required for male fertility and syncytial embryo development

(2009) Sarah P. Blagden et al.   DEVELOPMENTAL BIOLOGY

HuR recruits let-7/RISC to repress c-Myc expression

(2009) H. H. Kim et al.   GENES & DEVELOPMENT

Gene expression in early stage cervical cancer

(2008) Petra Biewenga et al.   GYNECOLOGIC ONCOLOGY

RNA-binding proteins in human genetic disease

(2008) Kiven E. Lukong et al.   TRENDS IN GENETICS