C. elegans-based screen identifies lysosome-damaging alkaloids that induce STAT3-dependent lysosomal cell death

Preoperative chemoradiotherapy with cisplatin and docetaxel for stage IIIB non-small-cell lung cancer: 10-year follow-up of the SAKK 16/01 trial

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Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion

(2016) Kai Liu et al.   JOURNAL OF CELL BIOLOGY

Protein kinase C controls lysosome biogenesis independently of mTORC1

(2016) Yang Li et al.   NATURE CELL BIOLOGY

Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism

(2015) Rushika M. Perera et al.   NATURE

Lysosomal ceramide generated by acid sphingomyelinase triggers cytosolic cathepsin B-mediated degradation of X-linked inhibitor of apoptosis protein in natural killer/T lymphoma cell apoptosis

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Sensing Cytosolic RpsL by Macrophages Induces Lysosomal Cell Death and Termination of Bacterial Infection

(2015) Wenhan Zhu et al.   PLoS Pathogens

The plant alkaloid voacamine induces apoptosis-independent autophagic cell death on both sensitive and multidrug resistant human osteosarcoma cells

(2014) Stefania Meschini et al.   Autophagy

Proteinase 3–dependent caspase-3 cleavage modulates neutrophil death and inflammation

(2014) Fabien Loison et al.   JOURNAL OF CLINICAL INVESTIGATION

Subversion of a Lysosomal Pathway Regulating Neutrophil Apoptosis by a Major Bacterial Toxin, Pyocyanin

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Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization

(2014) Timothy J. Sargeant et al.   NATURE CELL BIOLOGY

A new kind of cell suicide: mechanisms and functions of programmed necrosis

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Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

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The role of autophagy in neurodegenerative disease

(2013) Ralph A Nixon   NATURE MEDICINE

Impairment of lysosomal integrity by B10, a glycosylated derivative of betulinic acid, leads to lysosomal cell death and converts autophagy into a detrimental process

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Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors

(2012) Mahadeo A. Sukhai et al.   JOURNAL OF CLINICAL INVESTIGATION

JAK/STAT signaling in hematological malignancies

(2012) W Vainchenker et al.   ONCOGENE

Stat3 controls lysosomal-mediated cell death in vivo

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Indole alkaloids from Ervatamia chinensis

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Lipotoxicity-mediated cell dysfunction and death involve lysosomal membrane permeabilization and cathepsin L activity

(2010) Frankis G. Almaguel et al.   BRAIN RESEARCH

Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes

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Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

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Lysosomal membrane permeabilization in cell death

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