Impairment of lysosomal integrity by B10, a glycosylated derivative of betulinic acid, leads to lysosomal cell death and converts autophagy into a detrimental process

Vitamin E supplementation and mammalian lifespan

(2010) Ruth Banks et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The Double-Edged Sword of Autophagy Modulation in Cancer

(2009) E. White et al.   CLINICAL CANCER RESEARCH

Autophagy and metastasis: another double-edged sword

(2009) Candia M Kenific et al.   CURRENT OPINION IN CELL BIOLOGY

Targeting mitochondrial apoptosis by betulinic acid in human cancers

(2009) Simone Fulda et al.   DRUG DISCOVERY TODAY

Characterization of NVX-207, a novel betulinic acid-derived anti-cancer compound

(2009) M. Willmann et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Phosphatidylinositol 3-Kinase Inhibition Broadly Sensitizes Glioblastoma Cells to Death Receptor- and Drug-Induced Apoptosis

(2008) D. Opel et al.   CANCER RESEARCH

TNF-α- and TRAIL-resistant glioma cells undergo autophagy-dependent cell death induced by activated microglia

(2008) Rodrigo Mora et al.   GLIA

Cysteine Cathepsins Trigger Caspase-dependent Cell Death through Cleavage of Bid and Antiapoptotic Bcl-2 Homologues

(2008) Gabriela Droga-Mazovec et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents

(2008) Michael Degtyarev et al.   JOURNAL OF CELL BIOLOGY

Phospholipidosis and down-regulation of the PI3-K/PDK-1/Akt signalling pathway are vitamin E inhibitable events associated with 7-ketocholesterol-induced apoptosis

(2008) Anne Vejux et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE