Phenotypic deficits in the HIV-1 envelope are associated with the maturation of a V2-directed broadly neutralizing antibody lineage
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Phenotypic deficits in the HIV-1 envelope are associated with the maturation of a V2-directed broadly neutralizing antibody lineage
Authors
Keywords
Viral transmission and infection, HIV-1, Antibodies, Viral evolution, Cell fusion, Luciferase, Evolutionary immunology, Viral replication
Journal
PLoS Pathogens
Volume 14, Issue 1, Pages e1006825
Publisher
Public Library of Science (PLoS)
Online
2018-01-26
DOI
10.1371/journal.ppat.1006825
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Host controls of HIV broadly neutralizing antibody development
- (2017) Garnett Kelsoe et al. IMMUNOLOGICAL REVIEWS
- The HIV-1 envelope glycoprotein structure: nailing down a moving target
- (2017) Andrew B Ward et al. IMMUNOLOGICAL REVIEWS
- Immunologic characteristics of HIV-infected individuals who make broadly neutralizing antibodies
- (2017) Persephone Borrow et al. IMMUNOLOGICAL REVIEWS
- Antibody-virus co-evolution in HIV infection: paths for HIV vaccine development
- (2017) Mattia Bonsignori et al. IMMUNOLOGICAL REVIEWS
- Germline-targeting immunogens
- (2017) Leonidas Stamatatos et al. IMMUNOLOGICAL REVIEWS
- Identification and specificity of broadly neutralizing antibodies against HIV
- (2017) Laura E. McCoy et al. IMMUNOLOGICAL REVIEWS
- Delineating CD4 dependency of HIV-1: Adaptation to infect low level CD4 expressing target cells widens cellular tropism but severely impacts on envelope functionality
- (2017) David Beauparlant et al. PLoS Pathogens
- Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design
- (2016) Dennis R. Burton et al. Annual Review of Immunology
- HIV-Host Interactions: Implications for Vaccine Design
- (2016) Barton F. Haynes et al. Cell Host & Microbe
- Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch
- (2016) Daniel T. MacLeod et al. IMMUNITY
- Determinants of HIV-1 broadly neutralizing antibody induction
- (2016) Peter Rusert et al. NATURE MEDICINE
- Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption
- (2016) Katharine J. Bar et al. NEW ENGLAND JOURNAL OF MEDICINE
- CXCL13 is a plasma biomarker of germinal center activity
- (2016) Colin Havenar-Daughton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen
- (2016) J. G. Jardine et al. SCIENCE
- Enhanced clearance of HIV-1-infected cells by broadly neutralizing antibodies against HIV-1 in vivo
- (2016) C.-L. Lu et al. SCIENCE
- Approaches to the induction of HIV broadly neutralizing antibodies
- (2016) Penny L. Moore et al. Current Opinion in HIV and AIDS
- Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort
- (2016) Elise Landais et al. PLoS Pathogens
- Broadly Neutralizing Antibodies for HIV Eradication
- (2016) Kathryn E. Stephenson et al. Current HIV/AIDS Reports
- New approaches to HIV vaccine development
- (2015) Barton F Haynes CURRENT OPINION IN IMMUNOLOGY
- Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design
- (2015) Raiees Andrabi et al. IMMUNITY
- Inhibitory Effect of Individual or Combinations of Broadly Neutralizing Antibodies and Antiviral Reagents against Cell-Free and Cell-to-Cell HIV-1 Transmission
- (2015) Randi B. Gombos et al. JOURNAL OF VIROLOGY
- New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency
- (2015) Nicole A. Doria-Rose et al. JOURNAL OF VIROLOGY
- Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117
- (2015) Marina Caskey et al. NATURE
- Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies
- (2015) Jinal N Bhiman et al. NATURE MEDICINE
- Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design
- (2015) Jason Gorman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- HIV-1 neutralizing antibodies induced by native-like envelope trimers
- (2015) R. W. Sanders et al. SCIENCE
- Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection
- (2015) Rebecca M. Lynch et al. Science Translational Medicine
- Virological features associated with the development of broadly neutralizing antibodies to HIV-1
- (2015) Penny L. Moore et al. TRENDS IN MICROBIOLOGY
- HIV broadly neutralizing antibody targets
- (2015) Constantinos Kurt Wibmer et al. Current Opinion in HIV and AIDS
- Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design
- (2015) Jason Gorman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Different Infectivity of HIV-1 Strains Is Linked to Number of Envelope Trimers Required for Entry
- (2015) Oliver F. Brandenberg et al. PLoS Pathogens
- Capacity of Broadly Neutralizing Antibodies to Inhibit HIV-1 Cell-Cell Transmission Is Strain- and Epitope-Dependent
- (2015) Lucia Reh et al. PLoS Pathogens
- AliView: a fast and lightweight alignment viewer and editor for large datasets
- (2014) Anders Larsson BIOINFORMATICS
- Cooperation of B Cell Lineages in Induction of HIV-1-Broadly Neutralizing Antibodies
- (2014) Feng Gao et al. CELL
- Early Preservation of CXCR5+ PD-1+ Helper T Cells and B Cell Activation Predict the Breadth of Neutralizing Antibody Responses in Chronic HIV-1 Infection
- (2014) K. Cohen et al. JOURNAL OF VIROLOGY
- Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
- (2014) Nicole A. Doria-Rose et al. NATURE
- Neutralisation of HIV-1 cell-cell spread by human and llama antibodies
- (2014) Laura E McCoy et al. Retrovirology
- Immunogen design to focus the B-cell repertoire
- (2014) Quentin J. Sattentau Current Opinion in HIV and AIDS
- Development of broadly neutralizing antibodies from autologous neutralizing antibody responses in HIV infection
- (2014) Cynthia A. Derdeyn et al. Current Opinion in HIV and AIDS
- BEAST 2: A Software Platform for Bayesian Evolutionary Analysis
- (2014) Remco Bouckaert et al. PLoS Computational Biology
- Bayesian Inference of Sampled Ancestor Trees for Epidemiology and Fossil Calibration
- (2014) Alexandra Gavryushkina et al. PLoS Computational Biology
- Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection
- (2013) Peter Hraber et al. AIDS
- Antibody-based candidate therapeutics against HIV-1: implications for virus eradication and vaccine design
- (2013) Weizao Chen et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Human Circulating PD-1+CXCR3−CXCR5+ Memory Tfh Cells Are Highly Functional and Correlate with Broadly Neutralizing HIV Antibody Responses
- (2013) Michela Locci et al. IMMUNITY
- Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission
- (2013) Marine Malbec et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Retrovirus Glycoprotein Functionality Requires Proper Alignment of the Ectodomain and the Membrane-Proximal Cytoplasmic Tail
- (2013) Sanath Kumar Janaka et al. JOURNAL OF VIROLOGY
- Multiple Pathways of Escape from HIV Broadly Cross-Neutralizing V2-Dependent Antibodies
- (2013) P. L. Moore et al. JOURNAL OF VIROLOGY
- Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
- (2013) Hua-Xin Liao et al. NATURE
- Cell-to-Cell Transmission Can Overcome Multiple Donor and Target Cell Barriers Imposed on Cell-Free HIV
- (2013) Peng Zhong et al. PLoS One
- Antibodies in HIV-1 Vaccine Development and Therapy
- (2013) F. Klein et al. SCIENCE
- Rational Design of Vaccines to Elicit Broadly Neutralizing Antibodies to HIV-1
- (2013) P. D. Kwong et al. Cold Spring Harbor Perspectives in Medicine
- Viral Escape from HIV-1 Neutralizing Antibodies Drives Increased Plasma Neutralization Breadth through Sequential Recognition of Multiple Epitopes and Immunotypes
- (2013) Constantinos Kurt Wibmer et al. PLoS Pathogens
- Neutralization Resistance of Virological Synapse-Mediated HIV-1 Infection Is Regulated by the gp41 Cytoplasmic Tail
- (2012) N. D. Durham et al. JOURNAL OF VIROLOGY
- Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
- (2012) Jinghe Huang et al. NATURE
- Cell-Cell Transmission Enables HIV-1 to Evade Inhibition by Potent CD4bs Directed Antibodies
- (2012) Irene A. Abela et al. PLoS Pathogens
- Interaction of the gp120 V1V2 loop with a neighboring gp120 unit shields the HIV envelope trimer against cross-neutralizing antibodies
- (2011) Peter Rusert et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Potent and Broad Neutralization of HIV-1 Subtype C by Plasma Antibodies Targeting a Quaternary Epitope Including Residues in the V2 Loop
- (2011) P. L. Moore et al. JOURNAL OF VIROLOGY
- The Neutralization Breadth of HIV-1 Develops Incrementally over Four Years and Is Associated with CD4+ T Cell Decline and High Viral Load during Acute Infection
- (2011) E. S. Gray et al. JOURNAL OF VIROLOGY
- Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque
- (2011) L. M. Walker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding
- (2011) J. F. Scheid et al. SCIENCE
- DensiTree: making sense of sets of phylogenetic trees
- (2010) R. R. Bouckaert BIOINFORMATICS
- Rational antibody-based HIV-1 vaccine design: current approaches and future directions
- (2010) Laura M Walker et al. CURRENT OPINION IN IMMUNOLOGY
- Cross‐Reactive Neutralizing Humoral Immunity Does Not Protect from HIV Type 1 Disease Progression
- (2010) Zelda Euler et al. JOURNAL OF INFECTIOUS DISEASES
- Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1
- (2010) X. Wu et al. SCIENCE
- Quantitative Comparison of HTLV-1 and HIV-1 Cell-to-Cell Infection with New Replication Dependent Vectors
- (2010) Dmitriy Mazurov et al. PLoS Pathogens
- Divergent effects of cell environment on HIV entry inhibitor activity
- (2009) Peter Rusert et al. AIDS
- Breadth of Neutralizing Antibody Response to Human Immunodeficiency Virus Type 1 Is Affected by Factors Early in Infection but Does Not Influence Disease Progression
- (2009) A. Piantadosi et al. JOURNAL OF VIROLOGY
- Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target
- (2009) L. M. Walker et al. SCIENCE
- Frequency and Phenotype of Human Immunodeficiency Virus Envelope-Specific B Cells from Patients with Broadly Cross-Neutralizing Antibodies
- (2008) N. A. Doria-Rose et al. JOURNAL OF VIROLOGY
- Autologous Neutralizing Humoral Immunity and Evolution of the Viral Envelope in the Course of Subtype B Human Immunodeficiency Virus Type 1 Infection
- (2008) E. M. Bunnik et al. JOURNAL OF VIROLOGY
- Establishing a Cohort at High Risk of HIV Infection in South Africa: Challenges and Experiences of the CAPRISA 002 Acute Infection Study
- (2008) Francois van Loggerenberg et al. PLoS One
- CD4-Specific Designed Ankyrin Repeat Proteins Are Novel Potent HIV Entry Inhibitors with Unique Characteristics
- (2008) Andreas Schweizer et al. PLoS Pathogens
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now