Identification and specificity of broadly neutralizing antibodies against HIV
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Title
Identification and specificity of broadly neutralizing antibodies against HIV
Authors
Keywords
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Journal
IMMUNOLOGICAL REVIEWS
Volume 275, Issue 1, Pages 11-20
Publisher
Wiley
Online
2017-01-30
DOI
10.1111/imr.12484
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Note: Only part of the references are listed.- Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design
- (2016) Dennis R. Burton et al. Annual Review of Immunology
- HIV-1 Neutralizing Antibodies with Limited Hypermutation from an Infant
- (2016) Cassandra A. Simonich et al. CELL
- Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody
- (2016) Mattia Bonsignori et al. CELL
- Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies
- (2016) Bryan Briney et al. CELL
- Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice
- (2016) Amelia Escolano et al. CELL
- Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10
- (2016) Adriana Irimia et al. IMMUNITY
- A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans
- (2016) Devin Sok et al. IMMUNITY
- HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies
- (2016) Jon M. Steichen et al. IMMUNITY
- Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor
- (2016) Leopold Kong et al. IMMUNITY
- Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch
- (2016) Daniel T. MacLeod et al. IMMUNITY
- Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody
- (2016) R. Kong et al. SCIENCE
- Clonify: unseeded antibody lineage assignment from next-generation sequencing data
- (2016) Bryan Briney et al. Scientific Reports
- Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies
- (2016) Laura E. McCoy et al. Cell Reports
- Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site
- (2016) Todd Bradley et al. Cell Reports
- Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort
- (2016) Elise Landais et al. PLoS Pathogens
- An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability
- (2016) Marit J. van Gils et al. Nature Microbiology
- Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env
- (2015) Louise Scharf et al. CELL
- Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice
- (2015) Pia Dosenovic et al. CELL
- Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors
- (2015) Tongqing Zhou et al. CELL
- Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design
- (2015) Raiees Andrabi et al. IMMUNITY
- Diverse Antibody Genetic and Recognition Properties Revealed following HIV-1 Envelope Glycoprotein Immunization
- (2015) Ganesh E. Phad et al. JOURNAL OF IMMUNOLOGY
- New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency
- (2015) Nicole A. Doria-Rose et al. JOURNAL OF VIROLOGY
- Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design
- (2015) Jason Gorman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
- (2015) Young Do Kwon et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen
- (2015) J. G. Jardine et al. SCIENCE
- HIV-1 neutralizing antibodies induced by native-like envelope trimers
- (2015) R. W. Sanders et al. SCIENCE
- Virological features associated with the development of broadly neutralizing antibodies to HIV-1
- (2015) Penny L. Moore et al. TRENDS IN MICROBIOLOGY
- Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike
- (2015) Jeong Hyun Lee et al. Nature Communications
- Animal models in HIV-1 protection and therapy
- (2015) Ann J. Hessell et al. Current Opinion in HIV and AIDS
- Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design
- (2015) Jason Gorman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
- (2015) Young Do Kwon et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies
- (2015) Laura E. McCoy et al. PLoS Pathogens
- Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site
- (2015) Ema T. Crooks et al. PLoS Pathogens
- Structural Insights on the Role of Antibodies in HIV-1 Vaccine and Therapy
- (2014) Anthony P. West et al. CELL
- Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers
- (2014) Emilia Falkowska et al. IMMUNITY
- Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers
- (2014) Claudia Blattner et al. IMMUNITY
- Progress in HIV-1 vaccine development
- (2014) Barton F. Haynes et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Polyreactivity and Autoreactivity among HIV-1 Antibodies
- (2014) Mengfei Liu et al. JOURNAL OF VIROLOGY
- Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope
- (2014) Katie J. Doores et al. JOURNAL OF VIROLOGY
- Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface
- (2014) Jinghe Huang et al. NATURE
- Structure and immune recognition of trimeric pre-fusion HIV-1 Env
- (2014) Marie Pancera et al. NATURE
- Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
- (2014) Nicole A. Doria-Rose et al. NATURE
- Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex
- (2014) Devin Sok et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Promiscuous Glycan Site Recognition by Antibodies to the High-Mannose Patch of gp120 Broadens Neutralization of HIV
- (2014) D. Sok et al. Science Translational Medicine
- In vivo protection by broadly neutralizing HIV antibodies
- (2014) Marit J. van Gils et al. TRENDS IN MICROBIOLOGY
- Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike
- (2014) Louise Scharf et al. Cell Reports
- Molecular Evolution of Broadly Neutralizing Llama Antibodies to the CD4-Binding Site of HIV-1
- (2014) Laura E. McCoy et al. PLoS Pathogens
- Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies
- (2013) Tongqing Zhou et al. IMMUNITY
- HIV-1 neutralizing antibodies: understanding nature's pathways
- (2013) John R. Mascola et al. IMMUNOLOGICAL REVIEWS
- Neutralizing antibodies to HIV-1 induced by immunization
- (2013) Laura E. McCoy et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
- (2013) Hua-Xin Liao et al. NATURE
- Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
- (2013) Leopold Kong et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9
- (2013) Jean-Philippe Julien et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mining the antibodyome for HIV-1-neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains
- (2013) J. Zhu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts
- (2013) J. Zhu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies
- (2013) Devin Sok et al. PLoS Pathogens
- A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies
- (2013) Rogier W. Sanders et al. PLoS Pathogens
- Human Antibodies that Neutralize HIV-1: Identification, Structures, and B Cell Ontogenies
- (2012) Peter D. Kwong et al. IMMUNITY
- Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization
- (2012) Laura E. McCoy et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein
- (2012) Florian Klein et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Development of CD4 Binding Site Antibodies during HIV-1 Infection
- (2012) R. M. Lynch et al. JOURNAL OF VIROLOGY
- PGV04, an HIV-1 gp120 CD4 Binding Site Antibody, Is Broad and Potent in Neutralization but Does Not Induce Conformational Changes Characteristic of CD4
- (2012) Emilia Falkowska et al. JOURNAL OF VIROLOGY
- Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
- (2012) Jinghe Huang et al. NATURE
- Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo
- (2012) B. Moldt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120
- (2012) Anthony P. West et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies
- (2012) H. Mouquet et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Analysis of a Clonal Lineage of HIV-1 Envelope V2/V3 Conformational Epitope-Specific Broadly Neutralizing Antibodies and Their Inferred Unmutated Common Ancestors
- (2011) M. Bonsignori et al. JOURNAL OF VIROLOGY
- Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9
- (2011) Jason S. McLellan et al. NATURE
- Broad neutralization coverage of HIV by multiple highly potent antibodies
- (2011) Laura M. Walker et al. NATURE
- Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing
- (2011) X. Wu et al. SCIENCE
- Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding
- (2011) J. F. Scheid et al. SCIENCE
- A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield
- (2011) R. Pejchal et al. SCIENCE
- The Role of Antibodies in HIV Vaccines
- (2010) John R. Mascola et al. Annual Review of Immunology
- Rational antibody-based HIV-1 vaccine design: current approaches and future directions
- (2010) Laura M Walker et al. CURRENT OPINION IN IMMUNOLOGY
- Variable Loop Glycan Dependency of the Broad and Potent HIV-1-Neutralizing Antibodies PG9 and PG16
- (2010) Katie J. Doores et al. JOURNAL OF VIROLOGY
- Analysis of Memory B Cell Responses and Isolation of Novel Monoclonal Antibodies with Neutralizing Breadth from HIV-1-Infected Individuals
- (2010) Davide Corti et al. PLoS One
- Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1
- (2010) R. Pejchal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01
- (2010) T. Zhou et al. SCIENCE
- Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1
- (2010) X. Wu et al. SCIENCE
- A Limited Number of Antibody Specificities Mediate Broad and Potent Serum Neutralization in Selected HIV-1 Infected Individuals
- (2010) Laura M. Walker et al. PLoS Pathogens
- Tiered Categorization of a Diverse Panel of HIV-1 Env Pseudoviruses for Assessment of Neutralizing Antibodies
- (2009) M. S. Seaman et al. JOURNAL OF VIROLOGY
- Broadly Neutralizing Monoclonal Antibodies 2F5 and 4E10 Directed against the Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Protect against Mucosal Challenge by Simian-Human Immunodeficiency Virus SHIVBa-L
- (2009) A. J. Hessell et al. JOURNAL OF VIROLOGY
- Antibody Specificities Associated with Neutralization Breadth in Plasma from Human Immunodeficiency Virus Type 1 Subtype C-Infected Blood Donors
- (2009) E. S. Gray et al. JOURNAL OF VIROLOGY
- Human Immunodeficiency Virus Type 1 Elite Neutralizers: Individuals with Broad and Potent Neutralizing Activity Identified by Using a High-Throughput Neutralization Assay together with an Analytical Selection Algorithm
- (2009) M. D. Simek et al. JOURNAL OF VIROLOGY
- Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals
- (2009) Johannes F. Scheid et al. NATURE
- Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target
- (2009) L. M. Walker et al. SCIENCE
- Neutralizing antibodies against HIV-1: can we elicit them with vaccines and how much do we need?
- (2009) David C Montefiori et al. Current Opinion in HIV and AIDS
- Human Immunodeficiency Virus Type 1 Superinfection Occurs despite Relatively Robust Neutralizing Antibody Responses
- (2008) C. A. Blish et al. JOURNAL OF VIROLOGY
- Profiling the Specificity of Neutralizing Antibodies in a Large Panel of Plasmas from Patients Chronically Infected with Human Immunodeficiency Virus Type 1 Subtypes B and C
- (2008) J. M. Binley et al. JOURNAL OF VIROLOGY
- Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning
- (2007) Thomas Tiller et al. JOURNAL OF IMMUNOLOGICAL METHODS
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