Transcriptomes of Trypanosoma brucei rhodesiense from sleeping sickness patients, rodents and culture: Effects of strain, growth conditions and RNA preparation methods

Codon optimality, bias and usage in translation and mRNA decay

(2017) Gavin Hanson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Short poly(A) tails are a conserved feature of highly expressed genes

(2017) Sarah Azoubel Lima et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Short poly(A) tails are a conserved feature of highly expressed genes

(2017) Sarah Azoubel Lima et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Expression of the RNA-binding protein RBP10 promotes the bloodstream-form differentiation state in Trypanosoma brucei

(2017) Elisha Mugo et al.   PLoS Pathogens

Integrative analysis of the Trypanosoma brucei gene expression cascade predicts differential regulation of mRNA processing and unusual control of ribosomal protein expression

(2016) Enoch B. Antwi et al.   BMC GENOMICS

Trypanosoma brucei Parasites Occupy and Functionally Adapt to the Adipose Tissue in Mice

(2016) Sandra Trindade et al.   Cell Host & Microbe

De Novo Genome Assembly Shows Genome Wide Similarity between Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense

(2016) Mark Sistrom et al.   PLoS One

How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use?

(2016) Nicholas J. Schurch et al.   RNA

Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion

(2016) Stephen M. Christensen et al.   PLoS Neglected Tropical Diseases

Translation Regulation and RNA Granule Formation after Heat Shock of Procyclic Form Trypanosoma brucei: Many Heat-Induced mRNAs Are also Increased during Differentiation to Mammalian-Infective Forms

(2016) Igor Minia et al.   PLoS Neglected Tropical Diseases

Regulating a Post-Transcriptional Regulator: Protein Phosphorylation, Degradation and Translational Blockage in Control of the Trypanosome Stress-Response RNA-Binding Protein ZC3H11

(2016) Igor Minia et al.   PLoS Pathogens

The Dermis as a Delivery Site of Trypanosoma brucei for Tsetse Flies

(2016) Guy Caljon et al.   PLoS Pathogens

The skin is a significant but overlooked anatomical reservoir for vector-borne African trypanosomes

(2016) Paul Capewell et al.   eLife

SARTools: A DESeq2- and EdgeR-Based R Pipeline for Comprehensive Differential Analysis of RNA-Seq Data

(2016) Hugo Varet et al.   PLoS One

Comparative pathogenicity of Trypanosoma brucei rhodesiense strains in Swiss white mice and Mastomys natalensis rats

(2015) Margaret Wanjiku Muchiri et al.   ACTA TROPICA

Transcriptomes of newly-isolated Trypanosoma brucei rhodesiense reveal hundreds of mRNAs that are co-regulated with stumpy-form markers

(2015) Julius Mulindwa et al.   BMC GENOMICS

The within-host dynamics of African trypanosome infections

(2015) Keith R. Matthews et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Influence of RNA extraction methods and library selection schemes on RNA-seq data

(2014) Marc Sultan et al.   BMC GENOMICS

Extensive stage-regulation of translation revealed by ribosome profiling of Trypanosoma brucei

(2014) Bryan C Jensen et al.   BMC GENOMICS

Outcome of acute East African trypanosomiasis in a Polish traveller treated with pentamidine

(2014) Małgorzata Paul et al.   BMC INFECTIOUS DISEASES

Depletion of the Trypanosome Pumilio Domain Protein PUF2 or of Some Other Essential Proteins Causes Transcriptome Changes Related to Coding Region Length

(2014) Bhaskar Anand Jha et al.   EUKARYOTIC CELL

Trypanosoma bruceihistone H1 inhibits RNA polymerase I transcription and is important for parasite fitnessin vivo

(2014) Ana C. Pena et al.   MOLECULAR MICROBIOLOGY

Transcriptome-wide analysis of trypanosome mRNA decay reveals complex degradation kinetics and suggests a role for co-transcriptional degradation in determining mRNA levels

(2014) Abeer Fadda et al.   MOLECULAR MICROBIOLOGY

Comparative ribosome profiling reveals extensive translational complexity in different Trypanosoma brucei life cycle stages

(2014) Juan-José Vasquez et al.   NUCLEIC ACIDS RESEARCH

Trypanosome MKT1 and the RNA-binding protein ZC3H11: interactions and potential roles in post-transcriptional regulatory networks

(2014) Aditi Singh et al.   NUCLEIC ACIDS RESEARCH

Cyclical Appearance of African Trypanosomes in the Cerebrospinal Fluid: New Insights in How Trypanosomes Enter the CNS

(2014) Stefan Mogk et al.   PLoS One

Methods to Determine the Transcriptomes of Trypanosomes in Mixtures with Mammalian Cells: The Effects of Parasite Purification and Selective cDNA Amplification

(2014) Julius Mulindwa et al.   PLoS Neglected Tropical Diseases

A short bifunctional element operates to positively or negatively regulate ESAG9 expression in different developmental forms of Trypanosoma brucei

(2013) S. L. Monk et al.   JOURNAL OF CELL SCIENCE

Mapping the economic benefits to livestock keepers from intervening against bovine trypanosomosis in Eastern Africa

(2013) A.P.M. Shaw et al.   PREVENTIVE VETERINARY MEDICINE

Post-Transcriptional Regulation of the Trypanosome Heat Shock Response by a Zinc Finger Protein

(2013) Dorothea Droll et al.   PLoS Pathogens

Bloodstream form pre-adaptation to the tsetse fly in Trypanosoma brucei

(2013) Eva Rico et al.   Frontiers in Cellular and Infection Microbiology

Management of trypanosomiasis and leishmaniasis

(2012) M. P. Barrett et al.   BRITISH MEDICAL BULLETIN

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Untreated Human Infections by Trypanosoma brucei gambiense Are Not 100% Fatal

(2012) Vincent Jamonneau et al.   PLoS Neglected Tropical Diseases

Transmission Stages Dominate Trypanosome Within-Host Dynamics during Chronic Infections

(2011) Paula MacGregor et al.   Cell Host & Microbe

The Cell Cycle Regulated Transcriptome of Trypanosoma brucei

(2011) Stuart K. Archer et al.   PLoS One

Protocol Dependence of Sequencing-Based Gene Expression Measurements

(2011) Tal Raz et al.   PLoS One

The role of the 5'-3' exoribonuclease XRNA in transcriptome-wide mRNA degradation

(2011) T. Manful et al.   RNA

A novel phosphatase cascade regulates differentiation in Trypanosoma brucei via a glycosomal signaling pathway

(2010) B. Szoor et al.   GENES & DEVELOPMENT

A comparison between ribo-minus RNA-sequencing and polyA-selected RNA-sequencing

(2010) Peng Cui et al.   GENOMICS

Genome-wide analysis of mRNA abundance in two life-cycle stages of Trypanosoma brucei and identification of splicing and polyadenylation sites

(2010) Tim Nicolai Siegel et al.   NUCLEIC ACIDS RESEARCH

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Genome-wide expression profiling of in vivo-derived bloodstream parasite stages and dynamic analysis of mRNA alterations during synchronous differentiation in Trypanosoma brucei

(2009) Sarah Kabani et al.   BMC GENOMICS

Models for Trypanosoma evansi (surra), its control and economic impact on small-hold livestock owners in the Philippines

(2009) R.J. Dobson et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

A surface transporter family conveys the trypanosome differentiation signal

(2009) Samuel Dean et al.   NATURE