Evolution of chemokine receptors is driven by mutations in the sodium binding site

Universality of the Sodium Ion Binding Mechanism in Class A G-Protein-Coupled Receptors

(2018) Balaji Selvam et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intracellular Transfer of Na + in an Active-State G-Protein-Coupled Receptor

(2018) Owen N. Vickery et al.   STRUCTURE

Mechanisms of Regulation of the Chemokine-Receptor Network

(2017) Martin Stone et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The G Protein-Coupled Receptor UT of the Neuropeptide Urotensin II Displays Structural and Functional Chemokine Features

(2017) Hélène Castel et al.   Frontiers in Endocrinology

Overview and potential unifying themes of the atypical chemokine receptor family

(2016) Alessandro Vacchini et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Intracellular allosteric antagonism of the CCR9 receptor

(2016) Christine Oswald et al.   NATURE

Structural Mechanisms of Voltage Sensing in G Protein-Coupled Receptors

(2016) Owen N. Vickery et al.   STRUCTURE

Analysis of Chemokine Receptor Trafficking by Site-Specific Biotinylation

(2016) Marcel Liebick et al.   PLoS One

Allosteric Effects of Sodium Ion Binding on Activation of the M3 Muscarinic G-Protein-Coupled Receptor

(2015) Yinglong Miao et al.   BIOPHYSICAL JOURNAL

On the move: endocytic trafficking in cell migration

(2015) Tanja Maritzen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Biased GsVersusGqProteins and β-Arrestin Signaling in the NK1 Receptor Determined by Interactions in the Water Hydrogen Bond Network

(2015) Louise Valentin-Hansen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor

(2015) Haitao Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor

(2015) J. S. Burg et al.   SCIENCE

Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine

(2015) L. Qin et al.   SCIENCE

Mechanistic Insights into the Allosteric Modulation of Opioid Receptors by Sodium Ions

(2014) Yi Shang et al.   BIOCHEMISTRY

Chemokine signaling in development and disease

(2014) J. Wang et al.   DEVELOPMENT

Functional roles of evolutionary conserved motifs and residues in vertebrate chemokine receptors

(2014) Hisayuki Nomiyama et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Molecular control of δ-opioid receptor signalling

(2014) Gustavo Fenalti et al.   NATURE

The 2.1 Å Resolution Structure of Cyanopindolol-Bound β1-Adrenoceptor Identifies an Intramembrane Na+ Ion that Stabilises the Ligand-Free Receptor

(2014) Jennifer L. Miller-Gallacher et al.   PLoS One

Comparative analysis of sequence covariation methods to mine evolutionary hubs: Examples from selected GPCR families

(2014) Julien Pelé et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Allosteric sodium in class A GPCR signaling

(2014) Vsevolod Katritch et al.   TRENDS IN BIOCHEMICAL SCIENCES

CXCL12 chemokine and its receptors as major players in the interactions between immune and nervous systems

(2014) Alice Guyon   Frontiers in Cellular Neuroscience

The Role of Water and Sodium Ions in the Activation of the μ-Opioid Receptor

(2013) Shuguang Yuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Evolution and function of chemokine receptors in the immune system of lower vertebrates

(2013) Baubak Bajoghli   EUROPEAN JOURNAL OF IMMUNOLOGY

Biased Agonism as a Mechanism for Differential Signaling by Chemokine Receptors

(2013) Sudarshan Rajagopal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-1 exploits CCR5 conformational heterogeneity to escape inhibition by chemokines

(2013) Philippe Colin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation and dynamic network of the M2 muscarinic receptor

(2013) Y. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the CCR5 Chemokine Receptor-HIV Entry Inhibitor Maraviroc Complex

(2013) Q. Tan et al.   SCIENCE

The Role of a Sodium Ion Binding Site in the Allosteric Modulation of the A2A Adenosine G Protein-Coupled Receptor

(2013) Hugo Gutiérrez-de-Terán et al.   STRUCTURE

Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles

(2012) Robert B. Best et al.   Journal of Chemical Theory and Computation

Structure of the chemokine receptor CXCR1 in phospholipid bilayers

(2012) Sang Ho Park et al.   NATURE

High-resolution crystal structure of human protease-activated receptor 1

(2012) Cheng Zhang et al.   NATURE

Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

(2012) W. Liu et al.   SCIENCE

A family tree of vertebrate chemokine receptors for a unified nomenclature

(2011) Hisayuki Nomiyama et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

(2011) K. Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Studying functional dynamics in bio-molecules using accelerated molecular dynamics

(2011) Phineus R. L. Markwick et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Multidimensional Scaling Reveals the Main Evolutionary Pathways of Class A G-Protein-Coupled Receptors

(2011) Julien Pelé et al.   PLoS One

Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types

(2010) Jeffery B. Klauda et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists

(2010) B. Wu et al.   SCIENCE

Induced Effects of Sodium Ions on Dopaminergic G-Protein Coupled Receptors

(2010) Jana Selent et al.   PLoS Computational Biology

An Indel in Transmembrane Helix 2 Helps to Trace the Molecular Evolution of Class A G-Protein-Coupled Receptors

(2009) Julie Devillé et al.   JOURNAL OF MOLECULAR EVOLUTION

Factors Governing Metal−Ligand Distances and Coordination Geometries of Metal Complexes

(2009) Gopi Kuppuraj et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Ligand binding and micro-switches in 7TM receptor structures

(2009) Rie Nygaard et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

CHARMM-GUI: A web-based graphical user interface for CHARMM

(2008) Sunhwan Jo et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Data mining of metal ion environments present in protein structures

(2008) Heping Zheng et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Noncompetitive Antagonism and Inverse Agonism as Mechanism of Action of Nonpeptidergic Antagonists at Primate and Rodent CXCR3 Chemokine Receptors

(2008) D. Verzijl et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The roles of chemokine CXCL12 in embryonic and brain tumor angiogenesis

(2008) Meizhang Li et al.   SEMINARS IN CANCER BIOLOGY

Multiple roles of chemokine CXCL12 in the central nervous system: A migration from immunology to neurobiology

(2007) M LI et al.   PROGRESS IN NEUROBIOLOGY