The Role of Water and Sodium Ions in the Activation of the μ-Opioid Receptor

Structure-Function of the G Protein–Coupled Receptor Superfamily

(2012) Vsevolod Katritch et al.   Annual Review of Pharmacology and Toxicology

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

(2012) Aashish Manglik et al.   NATURE

High-resolution crystal structure of human protease-activated receptor 1

(2012) Cheng Zhang et al.   NATURE

The Role of Water in Activation Mechanism of Human N-Formyl Peptide Receptor 1 (FPR1) Based on Molecular Dynamics Simulations

(2012) Shuguang Yuan et al.   PLoS One

Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

(2012) W. Liu et al.   SCIENCE

Prediction of a Ligand-Binding Niche within a Human Olfactory Receptor by Combining Site-Directed Mutagenesis with Dynamic Homology Modeling

(2011) Lian Gelis et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Significance of G Protein-Coupled Receptor Crystallography for Drug Discovery

(2011) J. A. Salon et al.   PHARMACOLOGICAL REVIEWS

Study of a structurally similar kappa opioid receptor agonist and antagonist pair by molecular dynamics simulations

(2010) Michal Kolinski et al.   JOURNAL OF MOLECULAR MODELING

Induced Effects of Sodium Ions on Dopaminergic G-Protein Coupled Receptors

(2010) Jana Selent et al.   PLoS Computational Biology

Selectivity and Cooperativity of Modulatory Ions in a Neurotransmitter Receptor

(2009) Ranjit Vijayan et al.   BIOPHYSICAL JOURNAL

Conserved waters mediate structural and functional activation of family A (rhodopsin-like) G protein-coupled receptors

(2009) T. E. Angel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A G protein-coupled receptor at work: the rhodopsin model

(2009) Klaus Peter Hofmann et al.   TRENDS IN BIOCHEMICAL SCIENCES