Deciphering the Astrocyte Reaction in Alzheimer’s Disease

Gliotransmission: Beyond Black-and-White

(2018) Iaroslav Savtchouk et al.   JOURNAL OF NEUROSCIENCE

Multiple Lines of Evidence Indicate That Gliotransmission Does Not Occur under Physiological Conditions

(2018) Todd A. Fiacco et al.   JOURNAL OF NEUROSCIENCE

A bell-shaped dependence between amyloidosis and GABA accumulation in astrocytes in a mouse model of Alzheimer's disease

(2018) Bianca Brawek et al.   NEUROBIOLOGY OF AGING

Voluntary running enhances glymphatic influx in awake behaving, young mice

(2018) Stephanie von Holstein-Rathlou et al.   NEUROSCIENCE LETTERS

Activated forms of astrocytes with higher GLT-1 expression are associated with cognitive normal subjects with Alzheimer pathology in human brain

(2018) Eiji Kobayashi et al.   Scientific Reports

The Aging Astrocyte Transcriptome from Multiple Regions of the Mouse Brain

(2018) Matthew M. Boisvert et al.   Cell Reports

Cerebrospinal Fluid Level of YKL-40 Protein in Preclinical and Prodromal Alzheimer's Disease

(2018) Anna Antonell et al.   JOURNAL OF ALZHEIMERS DISEASE

Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease

(2017) Angela Gomez-Arboledas et al.   GLIA

APOE ε4/ε4 diminishes neurotrophic function of human iPSC-derived astrocytes

(2017) Jing Zhao et al.   HUMAN MOLECULAR GENETICS

YKL-40 (Chitinase 3-like I) is expressed in a subset of astrocytes in Alzheimer’s disease and other tauopathies

(2017) Marta Querol-Vilaseca et al.   Journal of Neuroinflammation

Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice

(2017) Pradoldej Sompol et al.   JOURNAL OF NEUROSCIENCE

Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition

(2017) Chia-Chen Liu et al.   JOURNAL OF NEUROSCIENCE

YKL-40 in the brain and cerebrospinal fluid of neurodegenerative dementias

(2017) Franc Llorens et al.   Molecular Neurodegeneration

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

(2017) Yang Shi et al.   NATURE

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

[18F]FDG PET signal is driven by astroglial glutamate transport

(2017) Eduardo R Zimmer et al.   NATURE NEUROSCIENCE

Identification of diverse astrocyte populations and their malignant analogs

(2017) Chia-Ching John Lin et al.   NATURE NEUROSCIENCE

CSF/serum albumin ratio in dementias: a cross-sectional study on 1861 patients

(2017) Tobias Skillbäck et al.   NEUROBIOLOGY OF AGING

Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence

(2017) Hua Chai et al.   NEURON

Interstitial solute transport in 3D reconstructed neuropil occurs by diffusion rather than bulk flow

(2017) Karl Erik Holter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Major Shifts in Glial Regional Identity Are a Transcriptional Hallmark of Human Brain Aging

(2017) Lilach Soreq et al.   Cell Reports

Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma

(2017) Alex J Smith et al.   eLife

Association of Perivascular Localization of Aquaporin-4 With Cognition and Alzheimer Disease in Aging Brains

(2017) Douglas M. Zeppenfeld et al.   JAMA Neurology

Voluntary Exercise Promotes Glymphatic Clearance of Amyloid Beta and Reduces the Activation of Astrocytes and Microglia in Aged Mice

(2017) Xiao-fei He et al.   Frontiers in Molecular Neuroscience

Glial Fibrillary Acidic Protein and Protein S-100B: Different Concentration Pattern of Glial Proteins in Cerebrospinal Fluid of Patients with Alzheimer's Disease and Creutzfeldt-Jakob Disease

(2017) Sarah Jesse et al.   JOURNAL OF ALZHEIMERS DISEASE

Plaque-Associated Local Toxicity Increases over the Clinical Course of Alzheimer Disease

(2016) Alberto Serrano-Pozo et al.   AMERICAN JOURNAL OF PATHOLOGY

Calcineurin proteolysis in astrocytes: Implications for impaired synaptic function

(2016) Melanie M. Pleiss et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Diverging longitudinal changes in astrocytosis and amyloid PET in autosomal dominant Alzheimer’s disease

(2016) Elena Rodriguez-Vieitez et al.   BRAIN

In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons

(2016) Philipp Mächler et al.   Cell Metabolism

Spatial model of convective solute transport in brain extracellular space does not support a “glymphatic” mechanism

(2016) Byung-Ju Jin et al.   JOURNAL OF GENERAL PHYSIOLOGY

Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease

(2016) H. Lian et al.   JOURNAL OF NEUROSCIENCE

Astrocytes mediate neurovascular signaling to capillary pericytes but not to arterioles

(2016) Anusha Mishra et al.   NATURE NEUROSCIENCE

Association of APOE with tau-tangle pathology with and without β-amyloid

(2016) Jose M. Farfel et al.   NEUROBIOLOGY OF AGING

Astrocytes from old Alzheimer's disease mice are impaired in Aβ uptake and in neuroprotection

(2016) Tal Iram et al.   NEUROBIOLOGY OF DISEASE

Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes

(2016) Won-Suk Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complement and microglia mediate early synapse loss in Alzheimer mouse models

(2016) S. Hong et al.   SCIENCE

The Rise and Fall of the d -Serine-Mediated Gliotransmission Hypothesis

(2016) Herman Wolosker et al.   TRENDS IN NEUROSCIENCES

Mapping synaptic glutamate transporter dysfunction in vivo to regions surrounding Aβ plaques by iGluSnFR two-photon imaging

(2016) J. K. Hefendehl et al.   Nature Communications

Green-Fluorescent Protein+ Astrocytes Attach to Beta-Amyloid Plaques in an Alzheimer Mouse Model and Are Sensitive for Clasmatodendrosis

(2016) Nina Daschil et al.   Frontiers in Aging Neuroscience

ARTAG in the basal forebrain: widening the constellation of astrocytic tau pathology

(2016) Alan King Lun Liu et al.   Acta Neuropathologica Communications

High Resolution Dissection of Reactive Glial Nets in Alzheimer’s Disease

(2016) David S. Bouvier et al.   Scientific Reports

Glymphatic solute transport does not require bulk flow

(2016) Mahdi Asgari et al.   Scientific Reports

Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

(2015) Gabor G. Kovacs et al.   ACTA NEUROPATHOLOGICA

APOEε2 is associated with milder clinical and pathological Alzheimer disease

(2015) Alberto Serrano-Pozo et al.   ANNALS OF NEUROLOGY

Vascular amyloidosis impairs the gliovascular unit in a mouse model of Alzheimer’s disease

(2015) Ian F. Kimbrough et al.   BRAIN

Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia

(2015) Aiqing Chen et al.   BRAIN

GFAP and vimentin deficiency alters gene expression in astrocytes and microglia in wild-type mice and changes the transcriptional response of reactive glia in mouse model for Alzheimer's disease

(2015) Willem Kamphuis et al.   GLIA

Glial fibrillar acidic protein in the cerebrospinal fluid of Alzheimer's disease, dementia with Lewy bodies, and frontotemporal lobar degeneration

(2015) Aiko Ishiki et al.   JOURNAL OF NEUROCHEMISTRY

The Effect of Body Posture on Brain Glymphatic Transport

(2015) H. Lee et al.   JOURNAL OF NEUROSCIENCE

The JAK/STAT3 Pathway Is a Common Inducer of Astrocyte Reactivity in Alzheimer's and Huntington's Diseases

(2015) L. Ben Haim et al.   JOURNAL OF NEUROSCIENCE

Deletion of aquaporin-4 in APP/PS1 mice exacerbates brain Aβ accumulation and memory deficits

(2015) Zhiqiang Xu et al.   Molecular Neurodegeneration

Alzheimer's disease is associated with altered expression of genes involved in immune response and mitochondrial processes in astrocytes

(2015) Shobana Sekar et al.   NEUROBIOLOGY OF AGING

Total glutamine synthetase levels in cerebrospinal fluid of Alzheimer's disease patients are unchanged

(2015) Nienke M. Timmer et al.   NEUROBIOLOGY OF AGING

Relationship between cortical thickness and cerebrospinal fluid YKL-40 in predementia stages of Alzheimer's disease

(2015) Daniel Alcolea et al.   NEUROBIOLOGY OF AGING

Astrocytes and microglia but not neurons preferentially generate N-terminally truncated Aβ peptides

(2015) Timo Jan Oberstein et al.   NEUROBIOLOGY OF DISEASE

Topological analyses in APP/PS1 mice reveal that astrocytes do not migrate to amyloid-β plaques

(2015) Elena Galea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early astrocytosis in autosomal dominant Alzheimer’s disease measured in vivo by multi-tracer positron emission tomography

(2015) Michael Schöll et al.   Scientific Reports

How astrocyte networks may contribute to cerebral metabolite clearance

(2015) Mahdi Asgari et al.   Scientific Reports

A Reduced Astrocyte Response to β-Amyloid Plaques in the Ageing Brain Associates with Cognitive Impairment

(2015) Ryan Mathur et al.   PLoS One

Impairment of paravascular clearance pathways in the aging brain

(2014) Benjamin T. Kress et al.   ANNALS OF NEUROLOGY

Failure of Perivascular Drainage of β-amyloid in Cerebral Amyloid Angiopathy

(2014) Cheryl A. Hawkes et al.   BRAIN PATHOLOGY

Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition

(2014) Gustavo A Rodriguez et al.   Journal of Neuroinflammation

Enhancing Astrocytic Lysosome Biogenesis Facilitates A  Clearance and Attenuates Amyloid Plaque Pathogenesis

(2014) Q. Xiao et al.   JOURNAL OF NEUROSCIENCE

Neuronal Transgene Expression in Dominant-Negative SNARE Mice

(2014) T. Fujita et al.   JOURNAL OF NEUROSCIENCE

Phenotypic Heterogeneity and Plasticity of Isocortical and Hippocampal Astrocytes in the Human Brain

(2014) A. A. Sosunov et al.   JOURNAL OF NEUROSCIENCE

Capillary pericytes regulate cerebral blood flow in health and disease

(2014) Catherine N. Hall et al.   NATURE

GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease

(2014) Seonmi Jo et al.   NATURE MEDICINE

Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction

(2014) Marie Orre et al.   NEUROBIOLOGY OF AGING

Looks Can Be Deceiving: Reconsidering the Evidence for Gliotransmission

(2014) Steven A. Sloan et al.   NEURON

Tonic inhibition in dentate gyrus impairs long-term potentiation and memory in an Alzheimer’s disease model

(2014) Zheng Wu et al.   Nature Communications

Metabotropic P2Y1 receptor signalling mediates astrocytic hyperactivity in vivo in an Alzheimer’s disease mouse model

(2014) Andrea Delekate et al.   Nature Communications

Proliferation in the Alzheimer Hippocampus Is due to Microglia, Not Astroglia, and Occurs at Sites of Amyloid Deposition

(2014) Michael W. Marlatt et al.   NEURAL PLASTICITY

Interstitial fluid drainage is impaired in ischemic stroke and Alzheimer’s disease mouse models

(2013) Michal Arbel-Ornath et al.   ACTA NEUROPATHOLOGICA

A Phenotypic Change But Not Proliferation Underlies Glial Responses in Alzheimer Disease

(2013) Alberto Serrano-Pozo et al.   AMERICAN JOURNAL OF PATHOLOGY

Astrocytes and Glutamate Homoeostasis in Alzheimer's Disease: A Decrease in Glutamine Synthetase, But Not in Glutamate Transporter-1, in the Prefrontal Cortex

(2013) Magdalena Kulijewicz-Nawrot et al.   ASN Neuro

Reactive glia show increased immunoproteasome activity in Alzheimer’s disease

(2013) Marie Orre et al.   BRAIN

Dissecting phenotypic traits linked to human resilience to Alzheimer’s pathology

(2013) Beatriz G. Perez-Nievas et al.   BRAIN

Reactive Glia in the Injured Brain Acquire Stem Cell Properties in Response to Sonic Hedgehog

(2013) Swetlana Sirko et al.   Cell Stem Cell

Examination of the Clinicopathologic Continuum of Alzheimer Disease in the Autopsy Cohort of the National Alzheimer Coordinating Center

(2013) Alberto Serrano-Pozo et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Differential Relationships of Reactive Astrocytes and Microglia to Fibrillar Amyloid Deposits in Alzheimer Disease

(2013) Alberto Serrano-Pozo et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Cerebral Arterial Pulsation Drives Paravascular CSF-Interstitial Fluid Exchange in the Murine Brain

(2013) J. J. Iliff et al.   JOURNAL OF NEUROSCIENCE

Amyloid- 1-42 Slows Clearance of Synaptically Released Glutamate by Mislocalizing Astrocytic GLT-1

(2013) A. Scimemi et al.   JOURNAL OF NEUROSCIENCE

D-Serine in Glia and Neurons Derives from 3-Phosphoglycerate Dehydrogenase

(2013) J. T. Ehmsen et al.   JOURNAL OF NEUROSCIENCE

Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways

(2013) Won-Suk Chung et al.   NATURE

Altered synapses and gliotransmission in Alzheimer's disease and AD model mice

(2013) Stanislaw Mitew et al.   NEUROBIOLOGY OF AGING

Sleep Drives Metabolite Clearance from the Adult Brain

(2013) L. Xie et al.   SCIENCE

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies

(2012) David J. Irwin et al.   BRAIN

Characterization of Thorn-Shaped Astrocytes in White Matter of Temporal Lobe in Alzheimer's Disease Brains

(2012) Irene López-González et al.   BRAIN PATHOLOGY

Mesial Temporal Astrocyte Tau Pathology in the MRC-CFAS Ageing Brain Cohort

(2012) G. Lace et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice

(2012) Andrew W. Kraft et al.   FASEB JOURNAL

Differential cell proliferation in the cortex of the appsweps1de9 alzheimer's disease mouse model

(2012) Willem Kamphuis et al.   GLIA

APOE genotype alters glial activation and loss of synaptic markers in mice

(2012) Yuangui Zhu et al.   GLIA

Characteristics of Aquaporin Expression Surrounding Senile Plaques and Cerebral Amyloid Angiopathy in Alzheimer Disease

(2012) Akihiko Hoshi et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Stable Size Distribution of Amyloid Plaques Over the Course of Alzheimer Disease

(2012) Alberto Serrano-Pozo et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Inhibition of the NFAT Pathway Alleviates Amyloid Beta Neurotoxicity in a Mouse Model of Alzheimer's Disease

(2012) E. Hudry et al.   JOURNAL OF NEUROSCIENCE

Targeting Astrocytes Ameliorates Neurologic Changes in a Mouse Model of Alzheimer's Disease

(2012) J. L. Furman et al.   JOURNAL OF NEUROSCIENCE

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

Apolipoprotein E, Especially Apolipoprotein E4, Increases the Oligomerization of Amyloid   Peptide

(2012) T. Hashimoto et al.   JOURNAL OF NEUROSCIENCE

Evidence for Astrocytosis in Prodromal Alzheimer Disease Provided by 11C-Deuterium-L-Deprenyl: A Multitracer PET Paradigm Combining 11C-Pittsburgh Compound B and 18F-FDG

(2012) S. F. Carter et al.   JOURNAL OF NUCLEAR MEDICINE

Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors

(2012) Nicola J. Allen et al.   NATURE

Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

(2012) Alix de Calignon et al.   NEURON

Astrocyte Senescence as a Component of Alzheimer’s Disease

(2012) Rekha Bhat et al.   PLoS One

Critical role of soluble amyloid-  for early hippocampal hyperactivity in a mouse model of Alzheimer's disease

(2012) M. A. Busche et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathological  -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice

(2012) K. C. Luk et al.   SCIENCE

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

Vascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice

(2011) Mario Merlini et al.   ACTA NEUROPATHOLOGICA

Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy

(2011) Cheryl A. Hawkes et al.   ACTA NEUROPATHOLOGICA

Reactive Glia not only Associates with Plaques but also Parallels Tangles in Alzheimer's Disease

(2011) Alberto Serrano-Pozo et al.   AMERICAN JOURNAL OF PATHOLOGY

Early Astrocytic Atrophy in the Entorhinal Cortex of a Triple Transgenic Animal Model of Alzheimer's Disease

(2011) Chia-Yu Yeh et al.   ASN Neuro

Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation

(2011) Akinobu Suzuki et al.   CELL

Astrocytes contain amyloid-β annular protofibrils in Alzheimer's disease brains

(2011) Cristian A. Lasagna-Reeves et al.   FEBS LETTERS

Multiple cellular and molecular mechanisms Are involved in human Aβ clearance by transplanted adult astrocytes

(2011) Rea Pihlaja et al.   GLIA

The contribution of activated astrocytes to Aβ production: Implications for Alzheimer's disease pathogenesis

(2011) Jie Zhao et al.   Journal of Neuroinflammation

Soluble A  Oligomers Inhibit Long-Term Potentiation through a Mechanism Involving Excessive Activation of Extrasynaptic NR2B-Containing NMDA Receptors

(2011) S. Li et al.   JOURNAL OF NEUROSCIENCE

Age-dependent decrease in glutamine synthetase expression in the hippocampal astroglia of the triple transgenic Alzheimer's disease mouse model: mechanism for deficient glutamatergic transmission?

(2011) Markel Olabarria et al.   Molecular Neurodegeneration

Microarray analysis of the astrocyte transcriptome in the aging brain: relationship to Alzheimer's pathology and APOE genotype

(2011) Julie E. Simpson et al.   NEUROBIOLOGY OF AGING

Aβ plaque-associated glial reaction as a determinant of apoptotic neuronal death and cortical gliogenesis: A study in APP mutant mice

(2011) Ilaria Luccarini et al.   NEUROSCIENCE LETTERS

Human apoE Isoforms Differentially Regulate Brain Amyloid-  Peptide Clearance

(2011) J. M. Castellano et al.   Science Translational Medicine

Cerebral amyloid angiopathy pathology and cognitive domains in older persons

(2010) Zoe Arvanitakis et al.   ANNALS OF NEUROLOGY

YKL-40: A Novel Prognostic Fluid Biomarker for Preclinical Alzheimer's Disease

(2010) Rebecca Craig-Schapiro et al.   BIOLOGICAL PSYCHIATRY

Concomitant astroglial atrophy and astrogliosis in a triple transgenic animal model of Alzheimer's disease

(2010) Markel Olabarria et al.   GLIA

Astrocytic Aβ1-42 uptake is determined by Aβ-aggregation state and the presence of amyloid-associated proteins

(2010) Henrietta M. Nielsen et al.   GLIA

Oligomers of Mutant Glial Fibrillary Acidic Protein (GFAP) Inhibit the Proteasome System in Alexander Disease Astrocytes, and the Small Heat Shock Protein αB-Crystallin Reverses the Inhibition

(2010) Guomei Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aberrant Detergent-Insoluble Excitatory Amino Acid Transporter 2 Accumulates in Alzheimer Disease

(2010) Randall L. Woltjer et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Aquaporin Expression in the Brains of Patients With or Without Cerebral Amyloid Angiopathy

(2010) Parham Moftakhar et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Amyloid   Induces the Morphological Neurodegenerative Triad of Spine Loss, Dendritic Simplification, and Neuritic Dystrophies through Calcineurin Activation

(2010) H.-Y. Wu et al.   JOURNAL OF NEUROSCIENCE

Long-term potentiation depends on release of d-serine from astrocytes

(2010) Christian Henneberger et al.   NATURE

Selective induction of astrocytic gliosis generates deficits in neuronal inhibition

(2010) Pavel I Ortinski et al.   NATURE NEUROSCIENCE

Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease

(2010) Martin Fuhrmann et al.   NATURE NEUROSCIENCE

Calcineurin inhibition with FK506 ameliorates dendritic spine density deficits in plaque-bearing Alzheimer model mice

(2010) Anete Rozkalne et al.   NEUROBIOLOGY OF DISEASE

Endothelin-Converting Enzyme-2 Is Increased in Alzheimer’s Disease and Up-Regulated by Aβ

(2009) Jennifer C. Palmer et al.   AMERICAN JOURNAL OF PATHOLOGY

SnapShot: Ca2+-Calcineurin-NFATSignaling

(2009) Gerald R. Crabtree et al.   CELL

Cognitive Decline in Alzheimer's Disease Is Associated with Selective Changes in Calcineurin/NFAT Signaling

(2009) H. M. Abdul et al.   JOURNAL OF NEUROSCIENCE

Uniquely Hominid Features of Adult Human Astrocytes

(2009) N. A. Oberheim et al.   JOURNAL OF NEUROSCIENCE

Vascular amyloid alters astrocytic water and potassium channels in mouse models and humans with Alzheimer's disease

(2009) D.M. Wilcock et al.   NEUROSCIENCE

Amyloid-  Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle

(2009) J.-E. Kang et al.   SCIENCE

Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice

(2009) K. V. Kuchibhotla et al.   SCIENCE

Close association of water channel AQP1 with amyloid-β deposition in Alzheimer disease brains

(2008) Tamako Misawa et al.   ACTA NEUROPATHOLOGICA

Binding and uptake of Aβ1-42 by primary human astrocytesin vitro

(2008) Henrietta M. Nielsen et al.   GLIA

Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways

(2008) G. Tang et al.   HUMAN MOLECULAR GENETICS

Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease

(2008) Melanie Meyer-Luehmann et al.   NATURE

Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain

(2008) J.E. Simpson et al.   NEUROBIOLOGY OF AGING

Aβ Plaques Lead to Aberrant Regulation of Calcium Homeostasis In Vivo Resulting in Structural and Functional Disruption of Neuronal Networks

(2008) Kishore V. Kuchibhotla et al.   NEURON

Expression of the translocator protein of 18 kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brain

(2008) M. Cosenza-Nashat et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease

(2008) M. A. Busche et al.   SCIENCE

MMP-2, -3 and -9 levels and activity are not related to Aβ load in the frontal cortex in Alzheimer's disease

(2007) S. Baig et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY