Tonic inhibition in dentate gyrus impairs long-term potentiation and memory in an Alzheimer’s disease model

Homeostatic Competition between Phasic and Tonic Inhibition

(2013) Xia Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A functional role for both γ-aminobutyric acid (GABA) transporter-1 and GABA transporter-3 in the modulation of extracellular GABA and GABAergic tonic conductances in the rat hippocampus

(2013) Flavie Kersanté et al.   JOURNAL OF PHYSIOLOGY-LONDON

Opposite actions of alcohol on tonic GABAA receptor currents mediated by nNOS and PKC activity

(2013) Joshua S Kaplan et al.   NATURE NEUROSCIENCE

Emerging roles of astrocytes in neural circuit development

(2013) Laura E. Clarke et al.   NATURE REVIEWS NEUROSCIENCE

Altered synapses and gliotransmission in Alzheimer's disease and AD model mice

(2013) Stanislaw Mitew et al.   NEUROBIOLOGY OF AGING

Multifunctional role of astrocytes as gatekeepers of neuronal energy supply

(2013) Jillian L. Stobart et al.   Frontiers in Cellular Neuroscience

Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model

(2012) Laure Verret et al.   CELL

Excitotoxicity: Bridge to various triggers in neurodegenerative disorders

(2012) Ankita Mehta et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Astrocytes and disease: a neurodevelopmental perspective

(2012) A. V. Molofsky et al.   GENES & DEVELOPMENT

γ-Aminobutyric Acid Type A (GABAA) Receptor α Subunits Play a Direct Role in SynapticVersusExtrasynaptic Targeting

(2012) Xia Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

Extrasynaptic GABAA Receptors: Their Function in the CNS and Implications for Disease

(2012) Stephen G. Brickley et al.   NEURON

Development of GABAergic inputs controls the contribution of maturing neurons to the adult hippocampal network

(2012) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Memory Deficits Induced by Inflammation Are Regulated by α5-Subunit-Containing GABAA Receptors

(2012) Dian-Shi Wang et al.   Cell Reports

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

(2011) Thomas J. Montine et al.   ACTA NEUROPATHOLOGICA

What the halted phase III γ-secretase inhibitor trial may (or may not) be telling us

(2011) Nina F. Schor   ANNALS OF NEUROLOGY

γ-Secretase Inhibitors and Modulators for the Treatment of Alzheimer's Disease: Disappointments and Hopes

(2011) Bruno P. Imbimbo et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Mechanisms of GABA release from human astrocytes

(2011) Moonhee Lee et al.   GLIA

Specific targeting of the GABA-A receptor α5 subtype by a selective inverse agonist restores cognitive deficits in Down syndrome mice

(2011) J Braudeau et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Astrocytes are GABAergic cells that modulate microglial activity

(2010) Moonhee Lee et al.   GLIA

 5GABAA Receptor Activity Sets the Threshold for Long-Term Potentiation and Constrains Hippocampus-Dependent Memory

(2010) L. J. Martin et al.   JOURNAL OF NEUROSCIENCE

Alzheimer's disease: clinical trials and drug development

(2010) Francesca Mangialasche et al.   LANCET NEUROLOGY

Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke

(2010) Andrew N. Clarkson et al.   NATURE

Astrocytes in Alzheimer’s disease

(2010) Alexei Verkhratsky et al.   Neurotherapeutics

Channel-Mediated Tonic GABA Release from Glia

(2010) S. Lee et al.   SCIENCE

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Preclinical and clinical pharmacology of the GABAA receptor α5 subtype-selective inverse agonist α5IA

(2009) John R. Atack   PHARMACOLOGY & THERAPEUTICS

Neuronal and non-neuronal GABA transporters as targets for antiepileptic drugs

(2009) Karsten K. Madsen et al.   PHARMACOLOGY & THERAPEUTICS

Glutamate Uptake Triggers Transporter-Mediated GABA Release from Astrocytes

(2009) László Héja et al.   PLoS One

A new amyloid β variant favoring oligomerization in Alzheimer's-type dementia

(2008) Takami Tomiyama et al.   ANNALS OF NEUROLOGY

Which GABAA Receptor Subunits Are Necessary for Tonic Inhibition in the Hippocampus?

(2008) J. Glykys et al.   JOURNAL OF NEUROSCIENCE

Synaptic integration and plasticity of new neurons in the adult hippocampus

(2008) Shaoyu Ge et al.   JOURNAL OF PHYSIOLOGY-LONDON

Targeted Activation of Astrocytes: A Potential Neuroprotective Strategy

(2008) Carole Escartin et al.   MOLECULAR NEUROBIOLOGY

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease

(2008) Ben A. Barres   NEURON

GABA, a forgotten gliotransmitter

(2008) María Cecilia Angulo et al.   PROGRESS IN NEUROBIOLOGY