Biomimetic Tissue Engineering: Tuning the Immune and Inflammatory Response to Implantable Biomaterials

Separate roles of IL-6 and oncostatin M in mouse macrophage polarization in vitro and in vivo

(2017) Anisha Dubey et al.   IMMUNOLOGY AND CELL BIOLOGY

Cytokine induction of sol–gel-derived TiO2 and SiO2 coatings on metallic substrates after implantation to rat femur

(2017) Wiktor Urbanski et al.   International Journal of Nanomedicine

Enhanced adhesion and in situ photothermal ablation of cancer cells in surface-functionalized electrospun microfiber scaffold with graphene oxide

(2017) Nicolò Mauro et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Biopolymers codelivering engineered T cells and STING agonists can eliminate heterogeneous tumors

(2017) Tyrel T. Smith et al.   JOURNAL OF CLINICAL INVESTIGATION

Concise Review: Biomimetic Functionalization of Biomaterials to Stimulate the Endogenous Healing Process of Cartilage and Bone Tissue

(2017) Francesca Taraballi et al.   Stem Cells Translational Medicine

Hyaluronic acid coatings as a simple and efficient approach to improve MSC homing toward the site of inflammation

(2017) Bruna Corradetti et al.   Scientific Reports

Immune tuning scaffold for the local induction of a pro-regenerative environment

(2017) Bruna Corradetti et al.   Scientific Reports

Immuno-Informed 3D Silk Biomaterials for Tailoring Biological Responses

(2016) Manishekhar Kumar et al.   ACS Applied Materials & Interfaces

IL-4 Release from a Biomimetic Scaffold for the Temporally Controlled Modulation of Macrophage Response

(2016) Silvia Minardi et al.   ANNALS OF BIOMEDICAL ENGINEERING

Spatially localized recruitment of anti-inflammatory monocytes by SDF-1α-releasing hydrogels enhances microvascular network remodeling

(2016) J.R. Krieger et al.   BIOMATERIALS

Enhanced Survival with Implantable Scaffolds That Capture Metastatic Breast Cancer Cells In Vivo

(2016) Shreyas S. Rao et al.   CANCER RESEARCH

Macrophages in Tissue Repair, Regeneration, and Fibrosis

(2016) Thomas A. Wynn et al.   IMMUNITY

The impact of surface chemistry modification on macrophage polarisation

(2016) Hassan M. Rostam et al.   IMMUNOBIOLOGY

Covalent Immobilization of Glycosaminoglycans to Reduce the Inflammatory Effects of Biomaterials

(2016) Guoying Zhou et al.   INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS

Incorporation of cerium oxide into hydroxyapatite coating regulates osteogenic activity of mesenchymal stem cell and macrophage polarization

(2016) Kai Li et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

Correlations between macrophage polarizing cytokines, inflammatory mediators, osteoclast activity, and toll-like receptors in tissues around aseptically loosened hip implants

(2016) Eemeli Jämsen et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

The biological response to orthopedic implants for joint replacement. II: Polyethylene, ceramics, PMMA, and the foreign body reaction

(2016) Emmanuel Gibon et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

The biological response to orthopaedic implants for joint replacement: Part I: Metals

(2016) Emmanuel Gibon et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Modulating macrophage polarization with divalent cations in nanostructured titanium implant surfaces

(2016) Chung-Ho Lee et al.   NANOTECHNOLOGY

Reparative inflammation takes charge of tissue regeneration

(2016) Michael Karin et al.   NATURE

Regenerative medicine: looking backward 10 years further on

(2016) Paul Kemp   Regenerative Medicine

Nanocomposite Hydrogels as Platform for Cells Growth, Proliferation, and Chemotaxis

(2016) Federica Fiorini et al.   Small

Biomimetic Concealing of PLGA Microspheres in a 3D Scaffold to Prevent Macrophage Uptake

(2016) Silvia Minardi et al.   Small

The Emerging Role of Nanotechnology in Cell and Organ Transplantation

(2016) Ennio Tasciotti et al.   TRANSPLANTATION

Engineering Immunomodulatory Biomaterials To Tune the Inflammatory Response

(2016) Ajaykumar Vishwakarma et al.   TRENDS IN BIOTECHNOLOGY

Chondroitin Sulfate Immobilized on a Biomimetic Scaffold Modulates Inflammation While Driving Chondrogenesis

(2016) Bruna Corradetti et al.   Stem Cells Translational Medicine

Exploring the Homeostatic and Sensory Roles of the Immune System

(2016) Rafael Elias Marques et al.   Frontiers in Immunology

Biomimetic collagenous scaffold to tune inflammation by targeting macrophages

(2016) Francesca Taraballi et al.   Journal of Tissue Engineering

PLGA-Mesoporous Silicon Microspheres for the in Vivo Controlled Temporospatial Delivery of Proteins

(2015) Silvia Minardi et al.   ACS Applied Materials & Interfaces

Monocyte and Macrophage Plasticity in Tissue Repair and Regeneration

(2015) Amitava Das et al.   AMERICAN JOURNAL OF PATHOLOGY

Immunomodulation by mesenchymal stem cells combats the foreign body response to cell-laden synthetic hydrogels

(2015) Mark D. Swartzlander et al.   BIOMATERIALS

Clinoenstatite coatings have high bonding strength, bioactive ion release, and osteoimmunomodulatory effects that enhance in vivo osseointegration

(2015) Chengtie Wu et al.   BIOMATERIALS

Sequential delivery of immunomodulatory cytokines to facilitate the M1-to-M2 transition of macrophages and enhance vascularization of bone scaffolds

(2015) Kara L. Spiller et al.   BIOMATERIALS

Evaluation of the osteoinductive potential of a bio-inspired scaffold mimicking the osteogenic niche for bone augmentation

(2015) Silvia Minardi et al.   BIOMATERIALS

Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms

(2015) Tamás Rőszer   MEDIATORS OF INFLAMMATION

Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates

(2015) Omid Veiseh et al.   NATURE MATERIALS

The Foreign Body Response

(2015) Melanie R. Major et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Osteoprogenitor Cells from Bone Marrow and Cortical Bone: Understanding How the Environment Affects Their Fate

(2015) Bruna Corradetti et al.   STEM CELLS AND DEVELOPMENT

In vivo capture and label-free detection of early metastatic cells

(2015) Samira M. Azarin et al.   Nature Communications

Impact of surface chemistry and topography on the function of antigen presenting cells

(2015) H. M. Rostam et al.   Biomaterials Science

Multidirectional Effects of Sr-, Mg-, and Si-Containing Bioceramic Coatings with High Bonding Strength on Inflammation, Osteoclastogenesis, and Osteogenesis

(2014) Chengtie Wu et al.   ACS Applied Materials & Interfaces

Electrically Conductive Chitosan/Carbon Scaffolds for Cardiac Tissue Engineering

(2014) Ana M. Martins et al.   BIOMACROMOLECULES

Bioengineered Implantable Scaffolds as a Tool to Study Stromal-Derived Factors in Metastatic Cancer Models

(2014) F. Bersani et al.   CANCER RESEARCH

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Implication of anti-inflammatory macrophages in regenerative moto-neuritogenesis: Promotion of myoblast migration and neural chemorepellent semaphorin 3A expression in injured muscle

(2014) Shohei Sakaguchi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Tri-iodo-l-thyronine promotes the maturation of human cardiomyocytes-derived from induced pluripotent stem cells

(2014) Xiulan Yang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Biopolymer implants enhance the efficacy of adoptive T-cell therapy

(2014) Sirkka B Stephan et al.   NATURE BIOTECHNOLOGY

Modulating the stem cell niche for tissue regeneration

(2014) Steven W Lane et al.   NATURE BIOTECHNOLOGY

Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies

(2014) Samir Mitragotri et al.   NATURE REVIEWS DRUG DISCOVERY

Citric Acid-based Hydroxyapatite Composite Scaffolds Enhance Calvarial Regeneration

(2014) Dawei Sun et al.   Scientific Reports

Biomaterials for Tissue Engineering

(2013) Esther J. Lee et al.   ANNALS OF BIOMEDICAL ENGINEERING

The use of bioinspired alterations in the glycosaminoglycan content of collagen–GAG scaffolds to regulate cell activity

(2013) Rebecca A. Hortensius et al.   BIOMATERIALS

PGS:Gelatin nanofibrous scaffolds with tunable mechanical and structural properties for engineering cardiac tissues

(2013) Mahshid Kharaziha et al.   BIOMATERIALS

The future of biologic coatings for orthopaedic implants

(2013) Stuart B. Goodman et al.   BIOMATERIALS

The behavior of cardiac progenitor cells on macroporous pericardium-derived scaffolds

(2013) Sareh Rajabi-Zeleti et al.   BIOMATERIALS

Lentivirus delivery of IL-10 to promote and sustain macrophage polarization towards an anti-inflammatory phenotype

(2013) R.M. Boehler et al.   BIOTECHNOLOGY AND BIOENGINEERING

Titanium surface hydrophilicity modulates the human macrophage inflammatory cytokine response

(2013) Mohammed A. Alfarsi et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Nano–bio effects: interaction of nanomaterials with cells

(2013) Liang-Chien Cheng et al.   Nanoscale

Sphingosine 1-phosphate receptor 3 regulates recruitment of anti-inflammatory monocytes to microvessels during implant arteriogenesis

(2013) Anthony O. Awojoodu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and Functional Maturation of Cardiomyocytes Derived from Human Pluripotent Stem Cells

(2013) Scott D. Lundy et al.   STEM CELLS AND DEVELOPMENT

A multilayered scaffold of a chitosan and gelatin hydrogel supported by a PCL core for cardiac tissue engineering

(2012) Seokwon Pok et al.   Acta Biomaterialia

A Highly Tunable Biocompatible and Multifunctional Biodegradable Elastomer

(2012) Maria José Nunes Pereira et al.   ADVANCED MATERIALS

Macrophages and fibrosis: How resident and infiltrating mononuclear phagocytes orchestrate all phases of tissue injury and repair

(2012) Maciej Lech et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Silk protein fibroin from Antheraea mylitta for cardiac tissue engineering

(2012) Chinmoy Patra et al.   BIOMATERIALS

Engineering biomaterials to integrate and heal: The biocompatibility paradigm shifts

(2012) James D. Bryers et al.   BIOTECHNOLOGY AND BIOENGINEERING

Cardiac repair using chitosan-hyaluronan/silk fibroin patches in a rat heart model with myocardial infarction

(2012) Nai-Hsin Chi et al.   CARBOHYDRATE POLYMERS

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage plasticity and polarization in tissue repair and remodelling

(2012) Alberto Mantovani et al.   JOURNAL OF PATHOLOGY

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

Implantable microenvironments to attract hematopoietic stem/cancer cells

(2012) J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomimicry in biomedical research

(2012) Ge Zhang   Organogenesis

Mesoporous Silicon-PLGA Composite Microspheres for the Double Controlled Release of Biomolecules for Orthopedic Tissue Engineering

(2011) Dongmei Fan et al.   ADVANCED FUNCTIONAL MATERIALS

Immune responses to implants – A review of the implications for the design of immunomodulatory biomaterials

(2011) Sandra Franz et al.   BIOMATERIALS

Inflammation and wound healing: the role of the macrophage

(2011) Timothy J. Koh et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

A Prospective, Randomized Evaluation of a Novel Everolimus-Eluting Coronary Stent

(2011) Gregg W. Stone et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Biomaterials for the Treatment of Myocardial Infarction

(2011) Aboli A. Rane et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

An algorithm-based topographical biomaterials library to instruct cell fate

(2011) H. V. Unadkat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomaterials Advances in Patches for Congenital Heart Defect Repair

(2011) Seokwon Pok et al.   Journal of Cardiovascular Translational Research

Biomaterials/Tissue Interactions: Possible Solutions to Overcome Foreign Body Response

(2010) Jacqueline M. Morais et al.   AAPS Journal

Dendritic cell responses to surface properties of clinical titanium surfaces

(2010) Peng Meng Kou et al.   Acta Biomaterialia

A platinum–chromium steel for cardiovascular stents

(2010) Barry J. O'Brien et al.   BIOMATERIALS

An elastomeric patch derived from poly(glycerol sebacate) for delivery of embryonic stem cells to the heart

(2010) Qi-Zhi Chen et al.   BIOMATERIALS

Biodegradable collagen patch with covalently immobilized VEGF for myocardial repair

(2010) Yasuo Miyagi et al.   BIOMATERIALS

A novel vascularized patch enhances cell survival and modifies ventricular remodeling in a rat myocardial infarction model

(2010) Qi Zhou et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Small intestinal submucosa gel as a potential scaffolding material for cardiac tissue engineering

(2009) Peter M. Crapo et al.   Acta Biomaterialia

Porous polycaprolactone scaffold for cardiac tissue engineering fabricated by selective laser sintering

(2009) W.Y. Yeong et al.   Acta Biomaterialia

Prosthetic Heart Valves

(2009) Philippe Pibarot et al.   CIRCULATION

Lymphocyte adhesion and interactions with biomaterial adherent macrophages and foreign body giant cells

(2009) David T. Chang et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Synthesis and characterization of elastic and macroporous chitosan–gelatin cryogels for tissue engineering

(2008) N KATHURIA et al.   Acta Biomaterialia

Evolving Concepts of Cardiac Valve Dynamics

(2008) Frederick J. Schoen   CIRCULATION

Giant cell formation and function

(2008) William G Brodbeck et al.   CURRENT OPINION IN HEMATOLOGY

Molecular mechanisms linking wound inflammation and fibrosis: knockdown of osteopontin leads to rapid repair and reduced scarring

(2008) Ryoichi Mori et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Foreign body reaction to biomaterials

(2008) James M. Anderson et al.   SEMINARS IN IMMUNOLOGY

Prosthetic heart valves: Catering for the few

(2007) Peter Zilla et al.   BIOMATERIALS