A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders
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Title
A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders
Authors
Keywords
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Journal
Scientific Reports
Volume 8, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-02-21
DOI
10.1038/s41598-018-22081-7
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Note: Only part of the references are listed.- Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice
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- Structure–Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase
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- Inhibitors of nicotinamide N-methyltransferase designed to mimic the methylation reaction transition state
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- Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization
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- Positive effects of GLP-1 receptor activation with liraglutide on pancreatic islet morphology and metabolic control in C57BL/KsJdb/dbmice with degenerative diabetes
- (2014) Rachel Charlotte Moffett et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity
- (2014) Daniel Kraus et al. NATURE
- Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide
- (2013) Kathrin Schmeisser et al. Nature Chemical Biology
- NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink
- (2013) Olesya A Ulanovskaya et al. Nature Chemical Biology
- Remodeling of Hepatic Metabolism and Hyperaminoacidemia in Mice Deficient in Proglucagon-Derived Peptides
- (2011) C. Watanabe et al. DIABETES
- Interferon-γ Elevates Nicotinamide N-Methyltransferase Activity and Nicotinamide Level in Human Glioma Cells
- (2010) Kazuo YAMADA et al. JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
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