A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders
出版年份 2018 全文链接
标题
A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders
作者
关键词
-
出版物
Scientific Reports
Volume 8, Issue 1, Pages -
出版商
Springer Nature
发表日期
2018-02-21
DOI
10.1038/s41598-018-22081-7
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice
- (2018) Harshini Neelakantan et al. BIOCHEMICAL PHARMACOLOGY
- Synthesis and evaluation of radiolabeled AGI-5198 analogues as candidate radiotracers for imaging mutant IDH1 expression in tumors
- (2018) Satish K. Chitneni et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Structure–Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase
- (2017) Harshini Neelakantan et al. JOURNAL OF MEDICINAL CHEMISTRY
- Inhibitors of nicotinamide N-methyltransferase designed to mimic the methylation reaction transition state
- (2017) Matthijs J. van Haren et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Nicotinamide N -Methyltransferase: More Than a Vitamin B3 Clearance Enzyme
- (2017) Pavlos Pissios TRENDS IN ENDOCRINOLOGY AND METABOLISM
- A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide N-Methyltransferase
- (2016) Matthijs J. van Haren et al. BIOCHEMISTRY
- Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance
- (2015) Aimo Kannt et al. DIABETOLOGIA
- SerumN1-Methylnicotinamide Is Associated With Obesity and Diabetes in Chinese
- (2015) Ming Liu et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Potential Involvement of NicotinamideN-Methyltransferase in the Pathogenesis of Metabolic Syndrome
- (2015) Rachela Giuliante et al. Metabolic Syndrome and Related Disorders
- Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization
- (2015) Shangyu Hong et al. NATURE MEDICINE
- Positive effects of GLP-1 receptor activation with liraglutide on pancreatic islet morphology and metabolic control in C57BL/KsJdb/dbmice with degenerative diabetes
- (2014) Rachel Charlotte Moffett et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity
- (2014) Daniel Kraus et al. NATURE
- Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide
- (2013) Kathrin Schmeisser et al. Nature Chemical Biology
- NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink
- (2013) Olesya A Ulanovskaya et al. Nature Chemical Biology
- Remodeling of Hepatic Metabolism and Hyperaminoacidemia in Mice Deficient in Proglucagon-Derived Peptides
- (2011) C. Watanabe et al. DIABETES
- Interferon-γ Elevates Nicotinamide N-Methyltransferase Activity and Nicotinamide Level in Human Glioma Cells
- (2010) Kazuo YAMADA et al. JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now