Inhibitors of nicotinamide N-methyltransferase designed to mimic the methylation reaction transition state

Structure–Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase

(2017) Harshini Neelakantan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Nicotinamide N-methyltransferase catalyses the N-methylation of the endogenous  -carboline norharman: evidence for a novel detoxification pathway

(2016) M. G. Thomas et al.   BIOCHEMICAL JOURNAL

A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide N-Methyltransferase

(2016) Matthijs J. van Haren et al.   BIOCHEMISTRY

Chemical Proteomic Profiling of Human Methyltransferases

(2016) Benjamin D. Horning et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nicotinamide N-methyltransferase increases complex I activity in SH-SY5Y cells via sirtuin 3

(2015) Karolina Y. Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SerumN1-Methylnicotinamide Is Associated With Obesity and Diabetes in Chinese

(2015) Ming Liu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Potential Involvement of NicotinamideN-Methyltransferase in the Pathogenesis of Metabolic Syndrome

(2015) Rachela Giuliante et al.   Metabolic Syndrome and Related Disorders

Synthesis and evaluation of protein arginine N-methyltransferase inhibitors designed to simultaneously occupy both substrate binding sites

(2015) Matthijs van Haren et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Design, synthesis, and kinetic analysis of potent protein N-terminal methyltransferase 1 inhibitors

(2015) Gang Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

YASARA View—molecular graphics for all devices—from smartphones to workstations

(2014) Elmar Krieger et al.   BIOINFORMATICS

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity

(2014) Daniel Kraus et al.   NATURE

Nicotinamide N-methyltransferase in Non-small Cell Lung Cancer: Promising Results for Targeted Anti-cancer Therapy

(2013) Davide Sartini et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Neuroprotective Effects of Nicotinamide N -Methyltransferase and its Metabolite 1-Methylnicotinamide

(2013) Zeinab H. Milani et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide

(2013) Kathrin Schmeisser et al.   Nature Chemical Biology

NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink

(2013) Olesya A Ulanovskaya et al.   Nature Chemical Biology

Correction: The Endocytic Adaptor Eps15 Controls Marginal Zone B Cell Numbers

(2013) Benedetta Pozzi et al.   PLoS One

A Functional-Group-Tolerant Catalytictrans Hydrogenation of Alkynes

(2012) Karin Radkowski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design, Synthesis, and Pharmacological Evaluation of Glutamate Carboxypeptidase II (GCPII) Inhibitors Based on Thioalkylbenzoic Acid Scaffolds

(2012) Doris Stoermer et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structural Basis of Substrate Recognition in Human NicotinamideN-Methyltransferase

(2011) Yi Peng et al.   BIOCHEMISTRY