Silibinin alleviates inflammation and induces apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes and has a therapeutic effect on arthritis in rats
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Silibinin alleviates inflammation and induces apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes and has a therapeutic effect on arthritis in rats
Authors
Keywords
-
Journal
Scientific Reports
Volume 8, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-02-13
DOI
10.1038/s41598-018-21674-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Silymarin/Silybin and Chronic Liver Disease: A Marriage of Many Years
- (2017) Alessandro Federico et al. MOLECULES
- IL-17-mediated mitochondrial dysfunction impairs apoptosis in rheumatoid arthritis synovial fibroblasts through activation of autophagy
- (2017) Eun Kyung Kim et al. Cell Death & Disease
- Age-dependent divergent effects of OX40L treatment on the development of diabetes in NOD mice
- (2016) Christine S. Haddad et al. AUTOIMMUNITY
- Beneficial effects of the naturally occurring flavonoid silibinin on the prostate cancer microenvironment: role of monocyte chemotactic protein-1 and immune cell recruitment
- (2016) Harold Ting et al. CARCINOGENESIS
- Autophagy: controlling cell fate in rheumatic diseases
- (2016) Jason S. Rockel et al. Nature Reviews Rheumatology
- Macrophage heterogeneity in the context of rheumatoid arthritis
- (2016) Irina A. Udalova et al. Nature Reviews Rheumatology
- Increased autophagy in fibroblast-like synoviocytes leads to immune enhancement potential in rheumatoid arthritis
- (2016) Ru Yang et al. Oncotarget
- Vitexin suppresses autophagy to induce apoptosis in hepatocellular carcinoma via activation of the JNK signaling pathway
- (2016) Zhen Wang et al. Oncotarget
- Amelioration of Experimental Autoimmune Arthritis Through Targeting of Synovial Fibroblasts by Intraarticular Delivery of MicroRNAs 140-3p and 140-5p
- (2016) Jia-Shiou Peng et al. Arthritis & Rheumatology
- GM-CSF: An immune modulatory cytokine that can suppress autoimmunity
- (2015) Palash Bhattacharya et al. CYTOKINE
- Dual Role of GM-CSF as a Pro-Inflammatory and a Regulatory Cytokine: Implications for Immune Therapy
- (2015) Palash Bhattacharya et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Regulation and function of SIRT1 in rheumatoid arthritis synovial fibroblasts
- (2015) Anna Engler et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- T cell subsets and their role in the pathogenesis of rheumatic disease
- (2014) Alison M. Gizinski et al. CURRENT OPINION IN RHEUMATOLOGY
- The flavonolignan-silymarin protects enzymatic, hematological, and immune system against γ-radiation-induced toxicity
- (2014) Manish Adhikari et al. ENVIRONMENTAL TOXICOLOGY
- Eye-mediated immune tolerance to Type II collagen in arthritis-prone strains of mice
- (2014) Shukkur M. Farooq et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Silymarin inhibits melanoma cell growth both in vitro and in vivo by targeting cell cycle regulators, angiogenic biomarkers and induction of apoptosis
- (2014) Mudit Vaid et al. MOLECULAR CARCINOGENESIS
- Myeloid Deletion of SIRT1 Aggravates Serum Transfer Arthritis in Mice via Nuclear Factor-κB Activation
- (2014) Young-Sool Hah et al. PLoS One
- Immunosuppressive Effect of Silymarin on Mitogen-Activated Protein Kinase Signalling Pathway: the Impact on T Cell Proliferation and Cytokine Production
- (2013) Marjan Gharagozloo et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- Silibinin Inhibits LPS-Induced Macrophage Activation by Blocking p38 MAPK in RAW 264.7 Cells
- (2013) Cha Kyung Youn et al. Biomolecules & Therapeutics
- Silibinin inhibits the production of pro-inflammatory cytokines through inhibition of NF-κB signaling pathway in HMC-1 human mast cells
- (2013) Beom-Rak Kim et al. INFLAMMATION RESEARCH
- Granulocyte–Macrophage Colony-Stimulating Factor Autoantibodies
- (2013) Grace Gathungu et al. INFLAMMATORY BOWEL DISEASES
- Simvastatin inhibits cysteine-rich protein 61 expression in rheumatoid arthritis synovial fibroblasts through the regulation of sirtuin-1/FoxO3a signaling
- (2012) Sang-Heng Kok et al. ARTHRITIS AND RHEUMATISM
- Silibinin modulates the NF-κb pathway and pro-inflammatory cytokine production by mononuclear cells from preeclamptic women
- (2012) Vanessa S. Innocenti Giorgi et al. JOURNAL OF REPRODUCTIVE IMMUNOLOGY
- Silibinin inhibits prostate cancer cells- and RANKL-induced osteoclastogenesis by targeting NFATc1, NF-κB, and AP-1 activation in RAW264.7 cells
- (2012) Chandagirikoppal V. Kavitha et al. MOLECULAR CARCINOGENESIS
- Granulocyte macrophage colony-stimulating factor treatment of a patient in myasthenic crisis: Effects on regulatory T cells
- (2012) Julie Rowin et al. MUSCLE & NERVE
- Sirtuins as regulators of metabolism and healthspan
- (2012) Riekelt H. Houtkooper et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Silibinin Attenuates Sulfur Mustard Analog-Induced Skin Injury by Targeting Multiple Pathways Connecting Oxidative Stress and Inflammation
- (2012) Neera Tewari-Singh et al. PLoS One
- Type II Collagen Induces Peripheral Tolerance in BALB/c Mice via the Generation of CD8+ T Regulatory Cells
- (2012) Shukkur M. Farooq et al. PLoS One
- SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance
- (2011) F. Niederer et al. ANNALS OF THE RHEUMATIC DISEASES
- Silibinin induces apoptosis via calpain-dependent AIF nuclear translocation in U87MG human glioma cell death
- (2011) Ji C Jeong et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Inhibition of Autophagy Enhances Anticancer Effects of Atorvastatin in Digestive Malignancies
- (2010) P.-M. Yang et al. CANCER RESEARCH
- Identification of hepatoprotective flavonolignans from silymarin
- (2010) S. J. Polyak et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Life and death partners: apoptosis, autophagy and the cross-talk between them
- (2009) A Eisenberg-Lerner et al. CELL DEATH AND DIFFERENTIATION
- Silymarin Inhibits In Vitro T-Cell Proliferation and Cytokine Production in Hepatitis C Virus Infection
- (2009) Chihiro Morishima et al. GASTROENTEROLOGY
- Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis
- (2009) Beatrix Bartok et al. IMMUNOLOGICAL REVIEWS
- Recent progress in the biology and physiology of sirtuins
- (2009) Toren Finkel et al. NATURE
- The Immunopathogenesis of Rheumatoid Arthritis
- (2008) John B. Imboden Annual Review of Pathology-Mechanisms of Disease
- The role of T lymphocytes in rheumatoid arthritis and other autoimmune diseases
- (2008) J. Claude Bennett ARTHRITIS AND RHEUMATISM
- Evidence that cytokines play a role in rheumatoid arthritis
- (2008) Fionula M. Brennan et al. JOURNAL OF CLINICAL INVESTIGATION
- Epigallocatechin-3-gallate inhibits IL-6 synthesis and suppresses transsignaling by enhancing soluble gp130 production
- (2008) S. Ahmed et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now