Amelioration of Experimental Autoimmune Arthritis Through Targeting of Synovial Fibroblasts by Intraarticular Delivery of MicroRNAs 140-3p and 140-5p

MicroRNA-140 Provides Robustness to the Regulation of Hypertrophic Chondrocyte Differentiation by the PTHrP-HDAC4 Pathway

(2015) Garyfallia Papaioannou et al.   JOURNAL OF BONE AND MINERAL RESEARCH

SDF-1 signaling: a promising target in rheumatic diseases

(2014) Amanda Villalvilla et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Anti-TNF therapy: past, present and future

(2014) C. Monaco et al.   INTERNATIONAL IMMUNOLOGY

Therapeutic targeting of microRNAs: current status and future challenges

(2014) Zhonghan Li et al.   NATURE REVIEWS DRUG DISCOVERY

MicroRNA-146a Provides Feedback Regulation of Lyme Arthritis but Not Carditis during Infection with Borrelia burgdorferi

(2014) Robert B. Lochhead et al.   PLoS Pathogens

Transcription Factor Snail Regulates Tumor Necrosis Factor α-Mediated Synovial Fibroblast Activation in the Rheumatoid Joint

(2014) Shih-Yao Chen et al.   Arthritis & Rheumatology

MicroRNAs-140-5p/140-3p Modulate Leydig Cell Numbers in the Developing Mouse Testis

(2013) J. Rakoczy et al.   BIOLOGY OF REPRODUCTION

MicroRNA-140-5p suppresses tumor growth and metastasis by targeting transforming growth factor β receptor 1 and fibroblast growth factor 9 in hepatocellular carcinoma

(2013) Hao Yang et al.   HEPATOLOGY

The Class III Histone Deacetylase Sirtuin 1 in Immune Suppression and Its Therapeutic Potential in Rheumatoid Arthritis

(2013) Sinyi Kong et al.   Journal of Genetics and Genomics

Sirtuin deacylases: a molecular link between metabolism and immunity

(2013) Nicolas Preyat et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The problem of choice: current biologic agents and future prospects in RA

(2013) Ernest H. Choy et al.   Nature Reviews Rheumatology

Progress in intra-articular therapy

(2013) Christopher H. Evans et al.   Nature Reviews Rheumatology

A Coregulatory Network of NR2F1 and microRNA-140

(2013) David Y. Chiang et al.   PLoS One

microRNA-140 Targets RALA and Regulates Chondrogenic Differentiation of Human Mesenchymal Stem Cells by Translational Enhancement of SOX9 and ACAN

(2013) Tommy A. Karlsen et al.   STEM CELLS AND DEVELOPMENT

Arthritis gene therapy and its tortuous path into the clinic

(2013) Christopher H. Evans et al.   Translational Research

NFAT3 and TGF-β/SMAD3 regulate the expression of miR-140 in osteoarthritis

(2013) Ginette Tardif et al.   ARTHRITIS RESEARCH & THERAPY

miR-140-3p regulation of TNF-α-induced CD38 expression in human airway smooth muscle cells

(2012) Joseph A. Jude et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Brief Report: Amelioration of collagen-induced arthritis in mice by lentivirus-mediated silencing of microRNA-223

(2012) Yuan-Tsung Li et al.   ARTHRITIS AND RHEUMATISM

Tumor Necrosis Factor α-Induced MicroRNA-18a Activates Rheumatoid Arthritis Synovial Fibroblasts Through a Feedback Loop in NF-κB Signaling

(2012) Michelle Trenkmann et al.   ARTHRITIS AND RHEUMATISM

MicroRNAs in the growth plate are responsive to nutritional cues: association between miR-140 and SIRT1

(2012) Rakefet Pando et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

siRNA-based therapeutic approaches for rheumatic diseases

(2012) Florence Apparailly et al.   Nature Reviews Rheumatology

Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors

(2012) Nunzio Bottini et al.   Nature Reviews Rheumatology

SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance

(2011) F. Niederer et al.   ANNALS OF THE RHEUMATIC DISEASES

What do microRNAs mean for rheumatoid arthritis?

(2011) Isabelle Duroux-Richard et al.   ARTHRITIS AND RHEUMATISM

The expression and function of microRNAs in chondrogenesis and osteoarthritis

(2011) Tracey E. Swingler et al.   ARTHRITIS AND RHEUMATISM

MicroRNA-22 and microRNA-140 suppress NF-κB activity by regulating the expression of NF-κB coactivators

(2011) Akemi Takata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evaluation of therapeutic targets in animal models of arthritis: How does it relate to rheumatoid arthritis?

(2010) Lisette Bevaart et al.   ARTHRITIS AND RHEUMATISM

Widespread regulatory activity of vertebrate microRNA* species

(2010) J.-S. Yang et al.   RNA

A Rac1 inhibitory peptide suppresses antibody production and paw swelling in the murine collagen-induced arthritis model of rheumatoid arthritis

(2010) Joana RF Abreu et al.   ARTHRITIS RESEARCH & THERAPY

MicroRNA-124a is a key regulator of proliferation and monocyte chemoattractant protein 1 secretion in fibroblast-like synoviocytes from patients with rheumatoid arthritis

(2009) Yuji Nakamachi et al.   ARTHRITIS AND RHEUMATISM

MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses

(2009) Shigeru Miyaki et al.   ARTHRITIS AND RHEUMATISM

Amelioration of experimental arthritis by a telomerase-dependent conditionally replicating adenovirus that targets synovial fibroblasts

(2009) Shih-Yao Chen et al.   ARTHRITIS AND RHEUMATISM

Fibroblast-like synoviocytes in inflammatory arthritis pathology: the emerging role of cadherin-11

(2009) Sook Kyung Chang et al.   IMMUNOLOGICAL REVIEWS

Collagen antibody-induced arthritis in mice: Development of a new arthritogenic 5-clone cocktail of monoclonal anti-type II collagen antibodies

(2009) Pilaiwanwadee Hutamekalin et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis

(2008) Joanna Stanczyk et al.   ARTHRITIS AND RHEUMATISM

Experimental identification of microRNA-140 targets by silencing and overexpressing miR-140

(2008) F. E. Nicolas et al.   RNA