Cryo-EM structure of 5-HT3A receptor in its resting conformation

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

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Structural basis for GABAA receptor potentiation by neurosteroids

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Crystal structure and dynamics of a lipid-induced potential desensitized-state of a pentameric ligand-gated channel

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Atomic Structure of the Cystic Fibrosis Transmembrane Conductance Regulator

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X-ray structure of the human α4β2 nicotinic receptor

(2016) Claudio L. Morales-Perez et al.   NATURE

Varenicline Interactions at the 5-HT3 Receptor Ligand Binding Site are Revealed by 5-HTBP

(2015) Kerry L. Price et al.   ACS Chemical Neuroscience

Glycine receptor mechanism elucidated by electron cryo-microscopy

(2015) Juan Du et al.   NATURE

Agonist and Antagonist Binding in Human Glycine Receptors

(2014) Rilei Yu et al.   BIOCHEMISTRY

Crystal structure of a human GABAA receptor

(2014) Paul S. Miller et al.   NATURE

X-ray structure of the mouse serotonin 5-HT3 receptor

(2014) Ghérici Hassaine et al.   NATURE

X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors

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Role of Serotonin 5-HT3 Receptors in Intestinal Inflammation

(2013) Shinichi Kato   BIOLOGICAL & PHARMACEUTICAL BULLETIN

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The Minimum M3-M4 Loop Length of Neurotransmitter-activated Pentameric Receptors Is Critical for the Structural Integrity of Cytoplasmic Portals

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Mutagenic Analysis of the Intracellular Portals of the Human 5-HT3A Receptor

(2013) Jane E. Carland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A distinct mechanism for activating uncoupled nicotinic acetylcholine receptors

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Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation

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(2013) Mareen Engel et al.   Frontiers in Cellular Neuroscience

5-HT3Receptors

(2012) Sarah C. R. Lummis   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting the 5-HT3 receptor in the treatment of irritable bowel syndrome

(2011) Robin C Spiller   CURRENT OPINION IN PHARMACOLOGY

Rings of Charge within the Extracellular Vestibule Influence Ion Permeation of the 5-HT3A Receptor

(2011) Matthew R. Livesey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Principles of activation and permeation in an anion-selective Cys-loop receptor

(2011) Ryan E. Hibbs et al.   NATURE

Anti-emetic drugs in oncology: pharmacology and individualization by pharmacogenetics

(2011) D. A. Perwitasari et al.   International Journal of Clinical Pharmacy

A Structural and Mutagenic Blueprint for Molecular Recognition of Strychnine and d-Tubocurarine by Different Cys-Loop Receptors

(2011) Marijke Brams et al.   PLOS BIOLOGY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Ligand-specific Conformational Changes in the α1 Glycine Receptor Ligand-binding Domain

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On the Origin of Ion Selectivity in the Cys-Loop Receptor Family

(2009) Steven M. Sine et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Water polygons in high-resolution protein crystal structures

(2009) Jonas Lee et al.   PROTEIN SCIENCE

Nicotinic Receptor Interloop Proline Anchors β1-β2 and Cys loops in Coupling Agonist Binding to Channel Gating

(2008) Won Yong Lee et al.   JOURNAL OF GENERAL PHYSIOLOGY

On the voltage-dependent Ca2+block of serotonin 5-HT3receptors: a critical role of intracellular phosphates

(2008) Yoav Noam et al.   JOURNAL OF PHYSIOLOGY-LONDON

Trafficking of 5-HT3and GABAAreceptors (Review)

(2008) C. N. Connolly   MOLECULAR MEMBRANE BIOLOGY

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

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