Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels

The unanticipated complexity of the selectivity-filter glutamates of nicotinic receptors

(2012) Gisela D Cymes et al.   Nature Chemical Biology

A locally closed conformation of a bacterial pentameric proton-gated ion channel

(2012) Marie S Prevost et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure and Pharmacology of Pentameric Receptor Channels: From Bacteria to Brain

(2012) Pierre-Jean Corringer et al.   STRUCTURE

General Anesthetics Predicted to Block the GLIC Pore with Micromolar Affinity

(2012) David N. LeBard et al.   PLoS Computational Biology

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Ion Selectivity Mechanism in a Bacterial Pentameric Ligand-Gated Ion Channel

(2011) Sebastian Fritsch et al.   BIOPHYSICAL JOURNAL

A Study of the Hydration of the Alkali Metal Ions in Aqueous Solution

(2011) Johan Mähler et al.   INORGANIC CHEMISTRY

In Glycine and GABAAChannels, Different Subunits Contribute Asymmetrically to Channel Conductance via Residues in the Extracellular Domain

(2011) Mirko Moroni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rings of Charge within the Extracellular Vestibule Influence Ion Permeation of the 5-HT3A Receptor

(2011) Matthew R. Livesey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel

(2011) Hugues Nury et al.   NATURE

Principles of activation and permeation in an anion-selective Cys-loop receptor

(2011) Ryan E. Hibbs et al.   NATURE

On the selective ion binding hypothesis for potassium channels

(2011) I. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decrypting the Sequence of Structural Events during the Gating Transition of Pentameric Ligand-Gated Ion Channels Based on an Interpolated Elastic Network Model

(2011) Wenjun Zheng et al.   PLoS Computational Biology

Ion Conduction in Ligand-Gated Ion Channels: Brownian Dynamics Studies of Four Recent Crystal Structures

(2010) Chen Song et al.   BIOPHYSICAL JOURNAL

Crystal Structures of a Cysteine-modified Mutant in Loop D of Acetylcholine-binding Protein

(2010) Marijke Brams et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Dynamics and Brownian Dynamics Investigation of Ion Permeation and Anesthetic Halothane Effects on a Proton-Gated Ion Channel

(2010) Mary Hongying Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural basis of open channel block in a prokaryotic pentameric ligand-gated ion channel

(2010) Ricarda J C Hilf et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Pore opening and closing of a pentameric ligand-gated ion channel

(2010) F. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue

(2010) H. Nury et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Energy and Structure of the M2 Helix in Acetylcholine Receptor-Channel Gating

(2009) Archana Jha et al.   BIOPHYSICAL JOURNAL

Cation-selective Pathway of OmpF Porin Revealed by Anomalous X-ray Diffraction

(2009) Balasundaresan Dhakshnamoorthy et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal Structure of the Extracellular Domain of a Bacterial Ligand-Gated Ion Channel

(2009) Hugues Nury et al.   JOURNAL OF MOLECULAR BIOLOGY

Water polygons in high-resolution protein crystal structures

(2009) Jonas Lee et al.   PROTEIN SCIENCE

Incorporating Dipolar Solvents with Variable Density in Poisson-Boltzmann Electrostatics

(2008) Cyril Azuara et al.   BIOPHYSICAL JOURNAL

An Ion Selectivity Filter in the Extracellular Domain of Cys-loop Receptors Reveals Determinants for Ion Conductance

(2008) Scott B. Hansen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

(2008) Nicolas Bocquet et al.   NATURE

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE