Enhancer of zeste homolog 2-catalysed H3K27 trimethylation plays a key role in acute-on-chronic liver failure via TNF-mediated pathway

Biological Effect of Licochalcone C on the Regulation of PI3K/Akt/eNOS and NF-κB/iNOS/NO Signaling Pathways in H9c2 Cells in Response to LPS Stimulation

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Overexpression of microRNA-138 alleviates human coronary artery endothelial cell injury and inflammatory response by inhibiting the PI3K/Akt/eNOS pathway

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Identification of expression quantitative trait loci (eQTLs) in human peripheral blood mononuclear cells (PBMCs) and shared with liver and brain

(2017) Pei He et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A Proof-of-Concept for Epigenetic Therapy of Tissue Fibrosis: Inhibition of Liver Fibrosis Progression by 3-Deazaneplanocin A

(2017) Müjdat Zeybel et al.   MOLECULAR THERAPY

Inflammation and epigenetic regulation in osteoarthritis

(2016) Jie Shen et al.   CONNECTIVE TISSUE RESEARCH

Hepatitis B virus dampens autophagy maturation via negative regulation of Rab7 expression

(2016) Tianhui Zhou et al.   BioScience Trends

Acute-on-Chronic Liver Failure

(2015) Sumeet K. Asrani et al.   Clinical Gastroenterology and Hepatology

Patients With Acute-on-Chronic Liver Failure Have Increased Numbers of Regulatory Immune Cells Expressing the Receptor Tyrosine Kinase MERTK

(2015) Christine Bernsmeier et al.   GASTROENTEROLOGY

Prostaglandin D2 and leukotriene E4 synergize to stimulate diverse TH2 functions and TH2 cell/neutrophil crosstalk

(2015) Luzheng Xue et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Acute-on-chronic liver failure: A new syndrome that will re-classify cirrhosis

(2015) Vicente Arroyo et al.   JOURNAL OF HEPATOLOGY

Acute-on-chronic liver failure

(2015) William Bernal et al.   LANCET

Mechanisms and pathways of innate immune activation and regulation in health and cancer

(2015) Jun Cui et al.   Human Vaccines & Immunotherapeutics

Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL) 2014

(2014) Shiv Kumar Sarin et al.   Hepatology International

Ezh2 Regulates Transcriptional and Posttranslational Expression of T-bet and Promotes Th1 Cell Responses Mediating Aplastic Anemia in Mice

(2014) Q. Tong et al.   JOURNAL OF IMMUNOLOGY

Epigenetically modulated LRRC33 acts as a negative physiological regulator for multiple Toll-like receptors

(2014) Xiaomin Su et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformation

(2014) Goro Sashida et al.   Nature Communications

The Polycomb Protein Ezh2 Regulates Differentiation and Plasticity of CD4+ T Helper Type 1 and Type 2 Cells

(2013) Damon J. Tumes et al.   IMMUNITY

Adenylyl Cyclase 6 Activation Negatively Regulates TLR4 Signaling through Lipid Raft-Mediated Endocytosis

(2013) W. Cai et al.   JOURNAL OF IMMUNOLOGY

Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation

(2013) Dongyi Xu et al.   NATURE NEUROSCIENCE

Interferon-γ deficiency reduces neointimal formation in a model of endoluminal endothelial injury combined with atherogenic diet

(2012) NASIM NIK TAVAKOLI et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Acute-on chronic liver failure

(2012) Rajiv Jalan et al.   JOURNAL OF HEPATOLOGY

The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms

(2012) Ludovica Ciuffreda et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

(2012) Michael T. McCabe et al.   NATURE

EZH2 Goes Solo

(2012) G. Cavalli   SCIENCE

Hepatitis B virus X protein regulates the mEZH2 promoter via the E2F1-binding site in AML12 cells

(2011) Xiao-Yan Shi et al.   Chinese Journal of Cancer

Soluble TNF, but not membrane TNF, is critical in LPS-induced hepatitis

(2010) Maria L. Olleros et al.   JOURNAL OF HEPATOLOGY

MeCP2 Controls an Epigenetic Pathway That Promotes Myofibroblast Transdifferentiation and Fibrosis

(2009) Jelena Mann et al.   GASTROENTEROLOGY

Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells

(2009) F. Sun et al.   MOLECULAR CANCER THERAPEUTICS

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

Language: Disputed definitions

(2008)   NATURE