Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformation
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Title
Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformation
Authors
Keywords
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Journal
Nature Communications
Volume 5, Issue 1, Pages -
Publisher
Springer Nature
Online
2014-06-23
DOI
10.1038/ncomms5177
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Note: Only part of the references are listed.- RUNX1/AML1 mutant collaborates with BMI1 overexpression in the development of human and murine myelodysplastic syndromes
- (2013) Y. Harada et al. BLOOD
- Clinical and biological implications of driver mutations in myelodysplastic syndromes
- (2013) E. Papaemmanuil et al. BLOOD
- Myeloproliferative Neoplasia Remodels the Endosteal Bone Marrow Niche into a Self-Reinforcing Leukemic Niche
- (2013) Koen Schepers et al. Cell Stem Cell
- Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders
- (2013) Tomoya Muto et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo
- (2013) Omar Abdel-Wahab et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Occupying Chromatin: Polycomb Mechanisms for Getting to Genomic Targets, Stopping Transcriptional Traffic, and Staying Put
- (2013) Jeffrey A. Simon et al. MOLECULAR CELL
- Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia
- (2012) S. Tanaka et al. BLOOD
- Loss of heterozygosity in 7q myeloid disorders: clinical associations and genomic pathogenesis
- (2012) A. Jerez et al. BLOOD
- Altered Microenvironmental Regulation of Leukemic and Normal Stem Cells in Chronic Myelogenous Leukemia
- (2012) Bin Zhang et al. CANCER CELL
- RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target Sites Independently of PRC2 and H3K27me3
- (2012) Lígia Tavares et al. CELL
- Epigenetic alterations in hematopoietic malignancies
- (2012) Young Rock Chung et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Epigenetic regulation of hematopoiesis
- (2012) Goro Sashida et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Validation of a Prognostic Model and the Impact of Mutations in Patients With Lower-Risk Myelodysplastic Syndromes
- (2012) Rafael Bejar et al. JOURNAL OF CLINICAL ONCOLOGY
- Direct Recruitment of Polycomb Repressive Complex 1 to Chromatin by Core Binding Transcription Factors
- (2012) Ming Yu et al. MOLECULAR CELL
- Ectopic expression of the histone methyltransferase Ezh2 in haematopoietic stem cells causes myeloproliferative disease
- (2012) A. Herrera-Merchan et al. Nature Communications
- methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles
- (2012) Altuna Akalin et al. GENOME BIOLOGY
- Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications
- (2011) Felix Krueger et al. BIOINFORMATICS
- Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells
- (2011) M. Mochizuki-Kashio et al. BLOOD
- Forced expression of the histone demethylase Fbxl10 maintains self-renewing hematopoietic stem cells
- (2011) Takaaki Konuma et al. EXPERIMENTAL HEMATOLOGY
- Clinical Effect of Point Mutations in Myelodysplastic Syndromes
- (2011) Rafael Bejar et al. NEW ENGLAND JOURNAL OF MEDICINE
- Polycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer
- (2010) Martin Sauvageau et al. Cell Stem Cell
- Evi-1 as a critical regulator of leukemic cells
- (2010) Susumu Goyama et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Mammalian target of rapamycin activation underlies HSC defects in autoimmune disease and inflammation in mice
- (2010) Chong Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
- (2010) Marc H. G. P. Raaijmakers et al. NATURE
- Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes
- (2010) Gorica Nikoloski et al. NATURE GENETICS
- Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
- (2010) Ryan D Morin et al. NATURE GENETICS
- Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
- (2010) Thomas Ernst et al. NATURE GENETICS
- IFNα activates dormant haematopoietic stem cells in vivo
- (2009) Marieke A. G. Essers et al. NATURE
- Identification of miR-145 and miR-146a as mediators of the 5q– syndrome phenotype
- (2009) Daniel T Starczynowski et al. NATURE MEDICINE
- AML1 mutations induced MDS and MDS/AML in a mouse BMT model
- (2008) N. Watanabe-Okochi et al. BLOOD
- EZH1 Mediates Methylation on Histone H3 Lysine 27 and Complements EZH2 in Maintaining Stem Cell Identity and Executing Pluripotency
- (2008) Xiaohua Shen et al. MOLECULAR CELL
- MDS: A Stem Cell Disorder--But What Exactly Is Wrong with the Primitive Hematopoietic Cells in This Disease?
- (2008) S. D. Nimer Hematology-American Society of Hematology Education Program
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