MYR1-Dependent Effectors Are the Major Drivers of a Host Cell’s Early Response to Toxoplasma , Including Counteracting MYR1-Independent Effects

Toxoplasma Effector Recruits the Mi-2/NuRD Complex to Repress STAT1 Transcription and Block IFN-γ-Dependent Gene Expression

(2016) Philipp Olias et al.   Cell Host & Microbe

Proteomic analysis reveals novel proteins associated with thePlasmodiumprotein exporter PTEX and a loss of complex stability upon truncation of the core PTEX component, PTEX150

(2016) Brendan Elsworth et al.   CELLULAR MICROBIOLOGY

Toxoplasma gondiiTgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-γ–mediated host defenses

(2016) Gabrielle Gay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Plasmodium species: master renovators of their host cells

(2016) Tania F. de Koning-Ward et al.   NATURE REVIEWS MICROBIOLOGY

A Novel Secreted Protein, MYR1, Is Central to Toxoplasma ’s Manipulation of Host Cells

(2016) Magdalena Franco et al.   mBio

In Vivo Biotinylation of the Toxoplasma Parasitophorous Vacuole Reveals Novel Dense Granule Proteins Important for Parasite Growth and Pathogenesis

(2016) Santhosh M. Nadipuram et al.   mBio

The Toxoplasma Dense Granule Proteins GRA17 and GRA23 Mediate the Movement of Small Molecules between the Host and the Parasitophorous Vacuole

(2015) Daniel A. Gold et al.   Cell Host & Microbe

The aspartyl protease TgASP5 mediates the export of theToxoplasmaGRA16 and GRA24 effectors into host cells

(2015) Aurélie Curt-Varesano et al.   CELLULAR MICROBIOLOGY

An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell

(2015) Michael J Coffey et al.   eLife

The Toxoplasma Pseudokinase ROP5 Forms Complexes with ROP18 and ROP17 Kinases that Synergize to Control Acute Virulence in Mice

(2014) Ronald D. Etheridge et al.   Cell Host & Microbe

TheToxoplasmaPseudokinase ROP5 Is an Allosteric Inhibitor of the Immunity-related GTPases

(2014) Michael L. Reese et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PTEX is an essential nexus for protein export in malaria parasites

(2014) Brendan Elsworth et al.   NATURE

PTEX component HSP101 mediates export of diverse malaria effectors into host erythrocytes

(2014) Josh R. Beck et al.   NATURE

Efficient Gene Disruption in Diverse Strains of Toxoplasma gondii Using CRISPR/CAS9

(2014) B. Shen et al.   mBio

Host Cell Subversion by Toxoplasma GRA16, an Exported Dense Granule Protein that Targets the Host Cell Nucleus and Alters Gene Expression

(2013) Alexandre Bougdour et al.   Cell Host & Microbe

Toxoplasma gondii Inhibits Gamma Interferon (IFN-γ)- and IFN-β-Induced Host Cell STAT1 Transcriptional Activity by Increasing the Association of STAT1 with DNA

(2013) Emily E. Rosowski et al.   INFECTION AND IMMUNITY

AToxoplasmadense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation

(2013) Laurence Braun et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Uncovering Common Principles in Protein Export of Malaria Parasites

(2012) Christof Grüring et al.   Cell Host & Microbe

Toxoplasma gondii Clonal Strains All Inhibit STAT1 Transcriptional Activity but Polymorphic Effectors Differentially Modulate IFNγ Induced Gene Expression and STAT1 Phosphorylation

(2012) Emily E. Rosowski et al.   PLoS One

The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response

(2012) Wendy Niedelman et al.   PLoS Pathogens

Strain-specific activation of the NF-κB pathway by GRA15, a novelToxoplasma gondiidense granule protein

(2011) Emily E. Rosowski et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Finding consistent patterns: A nonparametric approach for identifying differential expression in RNA-Seq data

(2011) Jun Li et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

Toxoplasma gondii Rhoptry Kinase ROP16 Activates STAT3 and STAT6 Resulting in Cytokine Inhibition and Arginase-1-Dependent Growth Control

(2011) Barbara A. Butcher et al.   PLoS Pathogens

An aspartyl protease directs malaria effector proteins to the host cell

(2010) Justin A. Boddey et al.   NATURE

Plasmepsin V licenses Plasmodium proteins for export into the host erythrocyte

(2010) Ilaria Russo et al.   NATURE

A newly discovered protein export machine in malaria parasites

(2009) Tania F. de Koning-Ward et al.   NATURE

BioVenn – a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams

(2008) Tim Hulsen et al.   BMC GENOMICS