Toxoplasma gondiiTgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-γ–mediated host defenses

Guanylate binding proteins directly attack Toxoplasma gondii via supramolecular complexes

(2016) Elisabeth Kravets et al.   eLife

The aspartyl protease TgASP5 mediates the export of theToxoplasmaGRA16 and GRA24 effectors into host cells

(2015) Aurélie Curt-Varesano et al.   CELLULAR MICROBIOLOGY

Toxoplasma 's ways of manipulating the host transcriptome via secreted effectors

(2015) Mohamed-Ali Hakimi et al.   CURRENT OPINION IN MICROBIOLOGY

An assessment of the human health impact of seven leading foodborne pathogens in the United States using disability adjusted life years

(2015) E. SCALLAN et al.   EPIDEMIOLOGY AND INFECTION

H3K4/H3K9me3 Bivalent Chromatin Domains Targeted by Lineage-Specific DNA Methylation Pauses Adipocyte Differentiation

(2015) Yoshihiro Matsumura et al.   MOLECULAR CELL

An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell

(2015) Michael J Coffey et al.   eLife

The Toxoplasma Pseudokinase ROP5 Forms Complexes with ROP18 and ROP17 Kinases that Synergize to Control Acute Virulence in Mice

(2014) Ronald D. Etheridge et al.   Cell Host & Microbe

Complex Immune Cell Interplay in the Gamma Interferon Response during Toxoplasma gondii Infection

(2014) Carolyn R. Sturge et al.   INFECTION AND IMMUNITY

Host Cell Subversion by Toxoplasma GRA16, an Exported Dense Granule Protein that Targets the Host Cell Nucleus and Alters Gene Expression

(2013) Alexandre Bougdour et al.   Cell Host & Microbe

A double take on bivalent promoters

(2013) P. Voigt et al.   GENES & DEVELOPMENT

Toxoplasma gondii Inhibits Gamma Interferon (IFN-γ)- and IFN-β-Induced Host Cell STAT1 Transcriptional Activity by Increasing the Association of STAT1 with DNA

(2013) Emily E. Rosowski et al.   INFECTION AND IMMUNITY

AToxoplasmadense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation

(2013) Laurence Braun et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Toxoplasma gondii Triggers Phosphorylation and Nuclear Translocation of Dendritic Cell STAT1 while Simultaneously Blocking IFNγ-Induced STAT1 Transcriptional Activity

(2013) Anne G. Schneider et al.   PLoS One

A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii

(2012) Masahiro Yamamoto et al.   IMMUNITY

The JAK-STAT Pathway at Twenty

(2012) George R. Stark et al.   IMMUNITY

Toxoplasma gondii Clonal Strains All Inhibit STAT1 Transcriptional Activity but Polymorphic Effectors Differentially Modulate IFNγ Induced Gene Expression and STAT1 Phosphorylation

(2012) Emily E. Rosowski et al.   PLoS One

Impaired Chromatin Remodelling at STAT1-Regulated Promoters Leads to Global Unresponsiveness of Toxoplasma gondii-Infected Macrophages to IFN-γ

(2012) Christine Lang et al.   PLoS Pathogens

The IRG protein-based resistance mechanism in mice and its relation to virulence in Toxoplasma gondii

(2011) Jonathan C Howard et al.   CURRENT OPINION IN MICROBIOLOGY

Toxoplasma gondii effectors are master regulators of the inflammatory response

(2011) Mariane B. Melo et al.   TRENDS IN PARASITOLOGY

Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains

(2009) Jonathan M Wojciak et al.   EMBO JOURNAL

Toxoplasma gondiiinfection and cerebral toxoplasmosis in HIV-infected patients

(2009) Vera Lucia Pereira-Chioccola et al.   Future Microbiology

A single polymorphic amino acid onToxoplasma gondiikinase ROP16 determines the direct and strain-specific activation of Stat3

(2009) Masahiro Yamamoto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Virulent Toxoplasma gondii Evade Immunity-Related GTPase-Mediated Parasite Vacuole Disruption within Primed Macrophages

(2009) Y. Zhao et al.   JOURNAL OF IMMUNOLOGY

Phosphorylation–acetylation switch in the regulation of STAT1 signaling

(2009) Oliver H. Krämer et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding

(2008) A. G. Robertson et al.   GENOME RESEARCH

Gr1+ Inflammatory Monocytes Are Required for Mucosal Resistance to the Pathogen Toxoplasma gondii

(2008) Ildiko R. Dunay et al.   IMMUNITY

Recruitment of Stat1 to chromatin is required for interferon-induced serine phosphorylation of Stat1 transactivation domain

(2008) Iwona Sadzak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA