Efficient Gene Disruption in Diverse Strains of Toxoplasma gondii Using CRISPR/CAS9

Role of Mouse and Human Autophagy Proteins in IFN- -Induced Cell-Autonomous Responses against Toxoplasma gondii

(2014) J. Ohshima et al.   JOURNAL OF IMMUNOLOGY

Toxoplasma GRA7 effector increases turnover of immunity-related GTPases and contributes to acute virulence in the mouse

(2014) A. Alaganan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic basis for phenotypic differences between different Toxoplasma gondii type I strains

(2013) Ninghan Yang et al.   BMC GENOMICS

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

(2013) Haoyi Wang et al.   CELL

Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients

(2013) Gerald Schwank et al.   Cell Stem Cell

Correction of a Genetic Disease in Mouse via Use of CRISPR-Cas9

(2013) Yuxuan Wu et al.   Cell Stem Cell

Efficient CRISPR/Cas9 genome editing with low off-target effects in zebrafish

(2013) A. Hruscha et al.   DEVELOPMENT

Cas9 as a versatile tool for engineering biology

(2013) Prashant Mali et al.   NATURE METHODS

Heritable genome editing in C. elegans via a CRISPR-Cas9 system

(2013) Ari E Friedland et al.   NATURE METHODS

Efficient genome editing in Caenorhabditis elegans by CRISPR-targeted homologous recombination

(2013) Changchun Chen et al.   NUCLEIC ACIDS RESEARCH

Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9

(2013) X. Ren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

Genetic Screens in Human Cells Using the CRISPR-Cas9 System

(2013) Tim Wang et al.   SCIENCE

RNA-programmed genome editing in human cells

(2013) Martin Jinek et al.   eLife

Modulation of innate immunity by Toxoplasma gondii virulence effectors

(2012) Christopher A. Hunter et al.   NATURE REVIEWS MICROBIOLOGY

CTCFBSDB 2.0: a database for CTCF-binding sites and genome organization

(2012) Jesse D. Ziebarth et al.   NUCLEIC ACIDS RESEARCH

Intramembrane proteolysis of Toxoplasma apical membrane antigen 1 facilitates host-cell invasion but is dispensable for replication

(2012) F. Parussini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Globally diverse Toxoplasma gondii isolates comprise six major clades originating from a small number of distinct ancestral lineages

(2012) C. Su et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

The Polymorphic Pseudokinase ROP5 Controls Virulence in Toxoplasma gondii by Regulating the Active Kinase ROP18

(2012) Michael S. Behnke et al.   PLoS Pathogens

Type II Toxoplasma gondii KU80 Knockout Strains Enable Functional Analysis of Genes Required for Cyst Development and Latent Infection

(2011) Barbara A. Fox et al.   EUKARYOTIC CELL

The Motility of a Human Parasite, Toxoplasma gondii, Is Regulated by a Novel Lysine Methyltransferase

(2011) Aoife T. Heaslip et al.   PLoS Pathogens

Phosphorylation of Immunity-Related GTPases by a Toxoplasma gondii-Secreted Kinase Promotes Macrophage Survival and Virulence

(2010) Sarah J. Fentress et al.   Cell Host & Microbe

Aldolase Is Essential for Energy Production and Bridging Adhesin-Actin Cytoskeletal Interactions during Parasite Invasion of Host Cells

(2009) G. Lucas Starnes et al.   Cell Host & Microbe

Phenotypic and Gene Expression Changes among Clonal Type I Strains ofToxoplasma gondii

(2009) Asis Khan et al.   EUKARYOTIC CELL

Efficient Gene Replacements inToxoplasma gondiiStrains Deficient for Nonhomologous End Joining

(2009) Barbara A. Fox et al.   EUKARYOTIC CELL

Tagging of Endogenous Genes in aToxoplasma gondiiStrain Lacking Ku80

(2009) My-Hang Huynh et al.   EUKARYOTIC CELL

Selection at a Single Locus Leads to Widespread Expansion of Toxoplasma gondii Lineages That Are Virulent in Mice

(2009) Asis Khan et al.   PLoS Genetics

Population Structure ofToxoplasma gondii: Clonal Expansion Driven by Infrequent Recombination and Selective Sweeps

(2008) L. David Sibley et al.   Annual Review of Microbiology