The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response

Globally diverse Toxoplasma gondii isolates comprise six major clades originating from a small number of distinct ancestral lineages

(2012) C. Su et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic analyses of atypical Toxoplasma gondii strains reveal a fourth clonal lineage in North America

(2011) Asis Khan et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

A Conserved Non-canonical Motif in the Pseudoactive Site of the ROP5 Pseudokinase Domain Mediates Its Effect on Toxoplasma Virulence

(2011) Michael L. Reese et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATF6β is a host cellular target of theToxoplasma gondiivirulence factor ROP18

(2011) Masahiro Yamamoto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Strain-specific activation of the NF-κB pathway by GRA15, a novelToxoplasma gondiidense granule protein

(2011) Emily E. Rosowski et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Determinants of GBP Recruitment to Toxoplasma gondii Vacuoles and the Parasitic Factors That Control It

(2011) Sebastian Virreira Winter et al.   PLoS One

Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence

(2011) M. L. Reese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseudokinases

(2011) M. S. Behnke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toxoplasma gondii effectors are master regulators of the inflammatory response

(2011) Mariane B. Melo et al.   TRENDS IN PARASITOLOGY

A Monomorphic Haplotype of Chromosome Ia Is Associated with Widespread Success in Clonal and Nonclonal Populations of Toxoplasma gondii

(2011) A. Khan et al.   mBio

Analyzing and minimizing PCR amplification bias in Illumina sequencing libraries

(2011) Daniel Aird et al.   GENOME BIOLOGY

Phosphorylation of Immunity-Related GTPases by a Toxoplasma gondii-Secreted Kinase Promotes Macrophage Survival and Virulence

(2010) Sarah J. Fentress et al.   Cell Host & Microbe

Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole

(2010) Aliaksandr Khaminets et al.   CELLULAR MICROBIOLOGY

NALP1 Influences Susceptibility to Human Congenital Toxoplasmosis, Proinflammatory Cytokine Response, and Fate ofToxoplasma gondii-Infected Monocytic Cells

(2010) William H. Witola et al.   INFECTION AND IMMUNITY

ToxoplasmaRhoptry Protein 16 (ROP16) Subverts Host Function by Direct Tyrosine Phosphorylation of STAT6

(2010) Yi-Ching Ong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P2X7 Receptor-Mediated Killing of an Intracellular Parasite, Toxoplasma gondii, by Human and Murine Macrophages

(2010) M. P. Lees et al.   JOURNAL OF IMMUNOLOGY

Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria

(2010) Sudha B. Singh et al.   NATURE CELL BIOLOGY

Phosphorylation of Mouse Immunity-Related GTPase (IRG) Resistance Proteins Is an Evasion Strategy for Virulent Toxoplasma gondii

(2010) Tobias Steinfeldt et al.   PLOS BIOLOGY

Sensitive and accurate detection of copy number variants using read depth of coverage

(2009) S. Yoon et al.   GENOME RESEARCH

Virulent Toxoplasma gondii Evade Immunity-Related GTPase-Mediated Parasite Vacuole Disruption within Primed Macrophages

(2009) Y. Zhao et al.   JOURNAL OF IMMUNOLOGY

Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P2 and PtdIns(3,4,5)P3 promotes immunity to mycobacteria

(2009) Sangeeta Tiwari et al.   NATURE IMMUNOLOGY

A Helical Membrane-Binding Domain Targets theToxoplasmaROP2 Family to the Parasitophorous Vacuole

(2009) Michael L. Reese et al.   TRAFFIC

Selection at a Single Locus Leads to Widespread Expansion of Toxoplasma gondii Lineages That Are Virulent in Mice

(2009) Asis Khan et al.   PLoS Genetics

Disruption of the Toxoplasma gondii Parasitophorous Vacuole by IFNγ-Inducible Immunity-Related GTPases (IRG Proteins) Triggers Necrotic Cell Death

(2009) Yang O. Zhao et al.   PLoS Pathogens

Autophagosome-Independent Essential Function for the Autophagy Protein Atg5 in Cellular Immunity to Intracellular Pathogens

(2008) Zijiang Zhao et al.   Cell Host & Microbe

Mapping short DNA sequencing reads and calling variants using mapping quality scores

(2008) H. Li et al.   GENOME RESEARCH

Extending genome-wide association studies to copy-number variation

(2008) S. A. McCarroll   HUMAN MOLECULAR GENETICS

Ocular Sequelae of Congenital Toxoplasmosis in Brazil Compared with Europe

(2008) Ruth E. Gilbert et al.   PLoS Neglected Tropical Diseases

Population structure and mouse-virulence of Toxoplasma gondii in Brazil

(2007) H.F.J. Pena et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY