Adaptive Mutations in Influenza A/California/07/2009 Enhance Polymerase Activity and Infectious Virion Production

Influenza Virus: Dealing with a Drifting and Shifting Pathogen

(2018) Hyunsuh Kim et al.   VIRAL IMMUNOLOGY

Antigenic and genetic characterization of influenza viruses circulating in Bulgaria during the 2015/2016 season

(2017) Neli Korsun et al.   INFECTION GENETICS AND EVOLUTION

Characterization of influenza A(H1N1)pdm09 viruses isolated from Nepalese and Indian outbreak patients in early 2015

(2017) Kazuya Nakamura et al.   Influenza and Other Respiratory Viruses

Population Diversity and Collective Interactions during Influenza Virus Infection

(2017) Christopher B. Brooke   JOURNAL OF VIROLOGY

Reduced accumulation of defective viral genomes contributes to severe outcome in influenza virus infected patients

(2017) Jasmina Vasilijevic et al.   PLoS Pathogens

A novel twelve class fluctuation test reveals higher than expected mutation rates for influenza A viruses

(2017) Matthew D Pauly et al.   eLife

Observed association between the HA1 mutation D222G in the 2009 pandemic influenza A(H1N1) virus and severe clinical outcome, Norway 2009-2010

(2017) A Kilander et al.   Eurosurveillance

Next generation sequencing for whole genome analysis and surveillance of influenza A viruses

(2016) Jana McGinnis et al.   JOURNAL OF CLINICAL VIROLOGY

Species difference in ANP32A underlies influenza A virus polymerase host restriction

(2016) Jason S. Long et al.   NATURE

Structural basis of an essential interaction between influenza polymerase and Pol II CTD

(2016) Maria Lukarska et al.   NATURE

Influenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis

(2016) Aartjan J. W. te Velthuis et al.   NATURE REVIEWS MICROBIOLOGY

Selective Degradation of Host RNA Polymerase II Transcripts by Influenza A Virus PA-X Host Shutoff Protein

(2016) Denys A. Khaperskyy et al.   PLoS Pathogens

Oligomerization and GTP-binding Requirements of MxA for Viral Target Recognition and Antiviral Activity against Influenza A Virus

(2015) Patricia E. Nigg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cryo-EM Structure of Influenza Virus RNA Polymerase Complex at 4.3 Å Resolution

(2015) Shenghai Chang et al.   MOLECULAR CELL

Influenza Virus Propagation in Embryonated Chicken Eggs

(2015) Rena Brauer et al.   Jove-Journal of Visualized Experiments

Viral determinants of influenza A virus host range

(2014) A. V. Cauldwell et al.   JOURNAL OF GENERAL VIROLOGY

Structure of influenza A polymerase bound to the viral RNA promoter

(2014) Alexander Pflug et al.   NATURE

Hemagglutinin mutation D222N of the 2009 pandemic H1N1 influenza virus alters receptor specificity without affecting virulence in mice

(2014) Weili Kong et al.   VIRUS RESEARCH

Influenza A Virus Host Shutoff Disables Antiviral Stress-Induced Translation Arrest

(2014) Denys A. Khaperskyy et al.   PLoS Pathogens

Sequence Analysis of In Vivo Defective Interfering-Like RNA of Influenza A H1N1 Pandemic Virus

(2013) K. Saira et al.   JOURNAL OF VIROLOGY

Receptor specificity does not affect replication or virulence of the 2009 pandemic H1N1 influenza virus in mice and ferrets

(2013) Seema S. Lakdawala et al.   VIROLOGY

Geneious Basic: An integrated and extendable desktop software platform for the organization and analysis of sequence data

(2012) M. Kearse et al.   BIOINFORMATICS

Myxovirus Resistance Gene A (MxA) Expression Suppresses Influenza A Virus Replication in Alpha Interferon-Treated Primate Cells

(2012) S. R. Matzinger et al.   JOURNAL OF VIROLOGY

Interferon-Inducible Protein Mx1 Inhibits Influenza Virus by Interfering with Functional Viral Ribonucleoprotein Complex Assembly

(2012) J. Verhelst et al.   JOURNAL OF VIROLOGY

Multifunctional Adaptive NS1 Mutations Are Selected upon Human Influenza Virus Evolution in the Mouse

(2012) Nicole E. Forbes et al.   PLoS One

Multiple amino acid substitutions involved in enhanced pathogenicity of LPAI H9N2 in mice

(2011) Zongde Zhang et al.   INFECTION GENETICS AND EVOLUTION

The Viral Nucleoprotein Determines Mx Sensitivity of Influenza A Viruses

(2011) P. Zimmermann et al.   JOURNAL OF VIROLOGY

Evolutionary Pathways of the Pandemic Influenza A (H1N1) 2009 in the UK

(2011) Monica Galiano et al.   PLoS One

Mutations in PA, NP, and HA of a pandemic (H1N1) 2009 influenza virus contribute to its adaptation to mice

(2011) Saori Sakabe et al.   VIRUS RESEARCH

Adaptation of Pandemic H1N1 Influenza Viruses in Mice

(2010) N. A. Ilyushina et al.   JOURNAL OF VIROLOGY

Evidence for Avian and Human Host Cell Factors That Affect the Activity of Influenza Virus Polymerase

(2010) O. Moncorge et al.   JOURNAL OF VIROLOGY

Animal Models for Influenza Virus Pathogenesis and Transmission

(2010) Nicole M. Bouvier et al.   Viruses-Basel

Variations in the Hemagglutinin of the 2009 H1N1 Pandemic Virus: Potential for Strains with Altered Virulence Phenotype?

(2010) Jianqiang Ye et al.   PLoS Pathogens

Alterations in receptor-binding properties of swine influenza viruses of the H1 subtype after isolation in embryonated chicken eggs

(2009) N. Takemae et al.   JOURNAL OF GENERAL VIROLOGY

Mutational Analysis of Conserved Amino Acids in the Influenza A Virus Nucleoprotein

(2009) Z. Li et al.   JOURNAL OF VIROLOGY

Adaptive Mutations Resulting in Enhanced Polymerase Activity Contribute to High Virulence of Influenza A Virus in Mice

(2009) T. Rolling et al.   JOURNAL OF VIROLOGY

The Polymerase Acidic Protein Gene of Influenza A Virus Contributes to Pathogenicity in a Mouse Model

(2009) M.-S. Song et al.   JOURNAL OF VIROLOGY

Transmission and Pathogenesis of Swine-Origin 2009 A(H1N1) Influenza Viruses in Ferrets and Mice

(2009) Taronna R. Maines et al.   SCIENCE

An Inhibitory Activity in Human Cells Restricts the Function of an Avian-like Influenza Virus Polymerase

(2008) Andrew Mehle et al.   Cell Host & Microbe

Influenza Virus Protecting RNA: an Effective Prophylactic and Therapeutic Antiviral

(2008) N. J. Dimmock et al.   JOURNAL OF VIROLOGY

The genomic and epidemiological dynamics of human influenza A virus

(2008) Andrew Rambaut et al.   NATURE

Two amino acid residues in the matrix protein M1 contribute to the virulence difference of H5N1 avian influenza viruses in mice

(2008) Shufang Fan et al.   VIROLOGY