Reduced accumulation of defective viral genomes contributes to severe outcome in influenza virus infected patients

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CCR5 deficiency predisposes to fatal outcome in influenza virus infection

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Adaptive Mutations That Occurred during Circulation in Humans of H1N1 Influenza Virus in the 2009 Pandemic Enhance Virulence in Mice

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Cryo-EM Structure of Influenza Virus RNA Polymerase Complex at 4.3 Å Resolution

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Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans

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An Unbiased Genetic Screen Reveals the Polygenic Nature of the Influenza Virus Anti-Interferon Response

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Accumulation of Human-Adapting Mutations during Circulation of A(H1N1)pdm09 Influenza Virus in Humans in the United Kingdom

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(2014) Alexander Pflug et al.   NATURE

Alveolar Macrophages Are Essential for Protection from Respiratory Failure and Associated Morbidity following Influenza Virus Infection

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A Systems Analysis Identifies a Feedforward Inflammatory Circuit Leading to Lethal Influenza Infection

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Defective Viral Genomes Arising In Vivo Provide Critical Danger Signals for the Triggering of Lung Antiviral Immunity

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A Novel Risk Factor for a Novel Virus: Obesity and 2009 Pandemic Influenza A (H1N1)

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Failure to activate the IFN-β promoter by a paramyxovirus lacking an interferon antagonist

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Defective interfering virus protects elderly mice from influenza

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Heterocellular induction of interferon by negative-sense RNA viruses

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(2009) Gabriele Neumann et al.   NATURE

Genetic trans-Complementation Establishes a New Model for Influenza Virus RNA Transcription and Replication

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Oligomerization of the influenza virus polymerase complex in vivo

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