Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification

Fresh Platinum Complexes with Promising Antitumor Activity

(2012) Xiaoyong Wang   Anti-Cancer Agents in Medicinal Chemistry

The CXXC motifs in the metal binding domains are required for ATP7B to mediate resistance to cisplatin

(2012) Roohangiz Safaei et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Mechanism of tumor resistance to cisplatin mediated by the copper transporter ATP7BThis paper is one of a selection of papers published in a Special Issue entitled CSBMCB 53rd Annual Meeting — Membrane Proteins in Health and Disease, and has undergone the Journal’s usual peer review process.

(2011) Oleg Y. Dmitriev   Biochemistry and Cell Biology

Distorted copper homeostasis with decreased sensitivity to cisplatin upon chaperone Atox1 deletion in Drosophila

(2011) Haiqing Hua et al.   BIOMETALS

Structure, solution chemistry, antiproliferative actions and protein binding properties of non-conventional platinum(ii) compounds with sulfur and phosphorus donors

(2011) Carolin Mügge et al.   DALTON TRANSACTIONS

Probing the Interaction of Cisplatin with the Human Copper Chaperone Atox1 by Solution and In-Cell NMR Spectroscopy

(2011) Fabio Arnesano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The quantitative proteome of a human cell line

(2011) M. Beck et al.   Molecular Systems Biology

Cisplatin binds human copper chaperone Atox1 and promotes unfolding in vitro

(2011) M. E. Palm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Glutaredoxin1 and Glutathione in Regulating the Activity of the Copper-transporting P-type ATPases, ATP7A and ATP7B

(2010) William C. J. Singleton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biological activity of enantiomeric complexes [PtCl2L2] (L2 is aromatic bisphosphanes and aromatic diamines)

(2010) Sophie Bombard et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Copper Transporters and the Cellular Pharmacology of the Platinum-Containing Cancer Drugs

(2010) S. B. Howell et al.   MOLECULAR PHARMACOLOGY

The soluble metal-binding domain of the copper transporter ATP7B binds and detoxifies cisplatin

(2009) Nataliya V. Dolgova et al.   BIOCHEMICAL JOURNAL

Extended X-Ray Absorption Fine Structure Study on Reaction of Anti-tumor Platinum Complexes with Reduced Glutathione

(2009) Makoto Obata et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Therapeutic Targeting of ATP7B in Ovarian Carcinoma

(2009) L. S. Mangala et al.   CLINICAL CANCER RESEARCH

Copper Transporter 2 Regulates the Cellular Accumulation and Cytotoxicity of Cisplatin and Carboplatin

(2009) B. G. Blair et al.   CLINICAL CANCER RESEARCH

Human copper transporters: mechanism, role in human diseases and therapeutic potential

(2009) Arnab Gupta et al.   Future Medicinal Chemistry

An NMR Study of the Interaction of the N-terminal Cytoplasmic Tail of the Wilson Disease Protein with Copper(I)-HAH1

(2009) Lucia Banci et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structures of Cisplatin Bound to a Human Copper Chaperone

(2009) Amie K. Boal et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Novel Role of Antioxidant-1 (Atox1) as a Copper-dependent Transcription Factor Involved in Cell Proliferation

(2008) Shinichi Itoh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trans labilization of am(m)ine ligands from platinum(II) complexes by cancer cell extracts

(2008) Yonit Kasherman et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Effects of the loss of Atox1 on the cellular pharmacology of cisplatin

(2008) Roohangiz Safaei et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Mechanism of Cu+-transporting ATPases: Soluble Cu+ chaperones directly transfer Cu+ to transmembrane transport sites

(2008) M. Gonzalez-Guerrero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA