Neurodevelopmental disorders: mechanisms and boundary definitions from genomes, interactomes and proteomes

Homozygous and heterozygous disruptions of ANK3: at the crossroads of neurodevelopmental and psychiatric disorders

(2013) Z. Iqbal et al.   HUMAN MOLECULAR GENETICS

Rare exonic deletions implicate the synaptic organizer Gephyrin (GPHN) in risk for autism, schizophrenia and seizures

(2013) Anath C. Lionel et al.   HUMAN MOLECULAR GENETICS

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

(2013)   LANCET

Developmental brain dysfunction: revival and expansion of old concepts based on new genetic evidence

(2013) Andres Moreno-De-Luca et al.   LANCET NEUROLOGY

The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky–Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIα

(2013) P. V. Ryder et al.   MOLECULAR BIOLOGY OF THE CELL

Mental health: On the spectrum

(2013) David Adam   NATURE

Variation and genetic control of protein abundance in humans

(2013) Linfeng Wu et al.   NATURE

Clinical and Molecular Genetics of Psychotic Depression

(2013) K. Domschke   SCHIZOPHRENIA BULLETIN

Epidemiological and Clinical Characterization Following a First Psychotic Episode in Major Depressive Disorder: Comparisons With Schizophrenia and Bipolar I Disorder in the Cavan-Monaghan First Episode Psychosis Study (CAMFEPS)

(2013) Olabisi Owoeye et al.   SCHIZOPHRENIA BULLETIN

Inferring high-confidence human protein-protein interactions

(2012) Xueping Yu et al.   BMC BIOINFORMATICS

CNVs: Harbingers of a Rare Variant Revolution in Psychiatric Genetics

(2012) Dheeraj Malhotra et al.   CELL

Phenotypic spectrum and genotype–phenotype correlations of NRXN1 exon deletions

(2012) Christian P Schaaf et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

New frontiers in human cell biology and medicine: Can pluripotent stem cells deliver?

(2012) Lawrence S.B. Goldstein   JOURNAL OF CELL BIOLOGY

Quantitative Proteomic and Genetic Analyses of the Schizophrenia Susceptibility Factor Dysbindin Identify Novel Roles of the Biogenesis of Lysosome-Related Organelles Complex 1

(2012) A. Gokhale et al.   JOURNAL OF NEUROSCIENCE

Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction

(2012) M Ayalew et al.   MOLECULAR PSYCHIATRY

Neurodevelopmental model of schizophrenia: update 2012

(2012) J L Rapoport et al.   MOLECULAR PSYCHIATRY

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

(2012) Brian J. O’Roak et al.   NATURE

Puzzling over schizophrenia: Schizophrenia as a pathway disease

(2012) Patrick F Sullivan   NATURE MEDICINE

Proteomics Tackling Schizophrenia as a Pathway Disorder

(2012) D. Martins-de-Souza   SCHIZOPHRENIA BULLETIN

Social cognition impairments in Asperger syndrome and schizophrenia

(2012) Tove Lugnegård et al.   SCHIZOPHRENIA RESEARCH

Removing bias against membrane proteins in interaction networks

(2011) Glauber C Brito et al.   BMC Systems Biology

Recent genomic advances in schizophrenia

(2011) JL Doherty et al.   CLINICAL GENETICS

Experimental models of Rett syndrome based on Mecp2 dysfunction

(2011) Gaston Calfa et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia

(2011) Julie Gauthier et al.   HUMAN GENETICS

The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse

(2011) Jennifer Larimore et al.   MOLECULAR BIOLOGY OF THE CELL

Cell Biology of the BLOC-1 Complex Subunit Dysbindin, a Schizophrenia Susceptibility Gene

(2011) Ariana P. Mullin et al.   MOLECULAR NEUROBIOLOGY

Lessons on the pathogenesis of aneurysm from heritable conditions

(2011) Mark E. Lindsay et al.   NATURE

v-SNARE Composition Distinguishes Synaptic Vesicle Pools

(2011) Zhaolin Hua et al.   NEURON

High Frequencies of De Novo CNVs in Bipolar Disorder and Schizophrenia

(2011) Dheeraj Malhotra et al.   NEURON

Theory of Mind and Neurodevelopmental Disorders of Childhood

(2011) BARIS KORKMAZ   PEDIATRIC RESEARCH

Synaptic Dysbindin-1 Reductions in Schizophrenia Occur in an Isoform-Specific Manner Indicating Their Subsynaptic Location

(2011) Konrad Talbot et al.   PLoS One

Autism Spectrum Disorders and Schizophrenia: Meta-Analysis of the Neural Correlates of Social Cognition

(2011) Gisela Sugranyes et al.   PLoS One

DISC1 at 10: connecting psychiatric genetics and neuroscience

(2011) David J. Porteous et al.   TRENDS IN MOLECULAR MEDICINE

Cross Talk among TGF-  Signaling Pathways, Integrins, and the Extracellular Matrix

(2011) J. S. Munger et al.   Cold Spring Harbor Perspectives in Biology

Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology

(2011) Elizabeth J. Rossin et al.   PLoS Genetics

Copy Number Variations in Schizophrenia: Critical Review and New Perspectives on Concepts of Genetics and Disease

(2010) Anne S. Bassett et al.   AMERICAN JOURNAL OF PSYCHIATRY

Research Domain Criteria (RDoC): Toward a New Classification Framework for Research on Mental Disorders

(2010) Thomas Insel et al.   AMERICAN JOURNAL OF PSYCHIATRY

The Diagnosis of Mental Disorders: The Problem of Reification

(2010) Steven E. Hyman   Annual Review of Clinical Psychology

The Neuroproteomics of Schizophrenia

(2010) Jane A. English et al.   BIOLOGICAL PSYCHIATRY

Is schizophrenia on the autism spectrum?

(2010) Bryan H. King et al.   BRAIN RESEARCH

Hermansky-Pudlak Protein Complexes, AP-3 and BLOC-1, Differentially Regulate Presynaptic Composition in the Striatum and Hippocampus

(2010) K. Newell-Litwa et al.   JOURNAL OF NEUROSCIENCE

22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia

(2010) Maria Karayiorgou et al.   NATURE REVIEWS NEUROSCIENCE

WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes

(2010) D. Jia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysbindin-1 in dorsolateral prefrontal cortex of schizophrenia cases is reduced in an isoform-specific manner unrelated to dysbindin-1 mRNA expression

(2009) J. Tang et al.   HUMAN MOLECULAR GENETICS

Childhood developmental disorders: an academic and clinical convergence point for psychiatry, neurology, psychology and pediatrics

(2009) Allan L. Reiss   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Proteomic analysis reveals novel binding partners of dysbindin, a schizophrenia-related protein

(2009) Takao Hikita et al.   JOURNAL OF NEUROCHEMISTRY

Roles of BLOC-1 and Adaptor Protein-3 Complexes in Cargo Sorting to Synaptic Vesicles

(2009) Karen Newell-Litwa et al.   MOLECULAR BIOLOGY OF THE CELL

Direct interaction of Dysbindin with the AP-3 complex via its μ subunit

(2009) Setsuko Taneichi-Kuroda et al.   NEUROCHEMISTRY INTERNATIONAL

Association analysis between schizophrenia and the AP-3 complex genes

(2009) Ryota Hashimoto et al.   NEUROSCIENCE RESEARCH

Dysbindin-1, a Schizophrenia-Related Protein, Functionally Interacts with the DNA- Dependent Protein Kinase Complex in an Isoform-Dependent Manner

(2009) Satoko Oyama et al.   PLoS One

Missing and spurious interactions and the reconstruction of complex networks

(2009) Roger Guimerà et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurexin 1 (NRXN1) Deletions in Schizophrenia

(2009) G. Kirov et al.   SCHIZOPHRENIA BULLETIN

Schizophrenia: The "BLOC" May Be in the Endosomes

(2009) P. V. Ryder et al.   Science Signaling

The dystrobrevin-binding protein 1 gene: features and networks

(2008) A Y Guo et al.   MOLECULAR PSYCHIATRY

Therapy of Marfan Syndrome

(2007) Daniel P. Judge et al.   Annual Review of Medicine

Reduced DTNBP1 (dysbindin-1) mRNA in the hippocampal formation of schizophrenia patients

(2007) Cynthia Shannon Weickert et al.   SCHIZOPHRENIA RESEARCH