TET2-dependent IL-6 induction mediated by the tumor microenvironment promotes tumor metastasis in osteosarcoma
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
TET2-dependent IL-6 induction mediated by the tumor microenvironment promotes tumor metastasis in osteosarcoma
Authors
Keywords
-
Journal
ONCOGENE
Volume 37, Issue 22, Pages 2903-2920
Publisher
Springer Nature
Online
2018-03-06
DOI
10.1038/s41388-018-0160-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Genome-wide analysis of somatic copy number alterations and chromosomal breakages in osteosarcoma
- (2017) Jan Smida et al. INTERNATIONAL JOURNAL OF CANCER
- Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-κB activation
- (2017) Sofia Avnet et al. INTERNATIONAL JOURNAL OF CANCER
- Germline and somatic genetics of osteosarcoma — connecting aetiology, biology and therapy
- (2017) D. Matthew Gianferante et al. Nature Reviews Endocrinology
- The histone demethylase KDM3A and its downstream target MCAM, promote Ewing Sarcoma cell migration and metastasis
- (2017) M Sechler et al. ONCOGENE
- Connecting the Metabolic and Immune Responses to Cancer
- (2017) Thomas R. Flint et al. TRENDS IN MOLECULAR MEDICINE
- Reprogramming of the Tumor in the Hypoxic Niche: The Emerging Concept and Associated Therapeutic Strategies
- (2017) Guan-Zhong Qiu et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Hypoxia regulates ABCG2activity through the activivation of ERK1/2/HIF-1α and contributes to chemoresistance in pancreatic cancer cells
- (2016) Xiaodan He et al. CANCER BIOLOGY & THERAPY
- Cancer development, chemoresistance, epithelial to mesenchymal transition and stem cells: A snapshot of IL-6 mediated involvement
- (2016) Rashmi Bharti et al. CANCER LETTERS
- Molecular or Metabolic Reprograming: What Triggers Tumor Subtypes?
- (2016) Katherine Eason et al. CANCER RESEARCH
- Jmjd2/Kdm4 demethylases are required for expression ofIl3raand survival of acute myeloid leukemia cells
- (2016) Karl Agger et al. GENES & DEVELOPMENT
- Role of TET enzymes in DNA methylation, development, and cancer
- (2016) Kasper Dindler Rasmussen et al. GENES & DEVELOPMENT
- Mortalin-mediated and ERK-controlled targeting of HIF-1α to mitochondria confers resistance to apoptosis under hypoxia
- (2016) Ilias Mylonis et al. JOURNAL OF CELL SCIENCE
- The histone demethylase KDM4B regulates peritoneal seeding of ovarian cancer
- (2016) C Wilson et al. ONCOGENE
- Interleukin-6 promotes tumor progression in colitis-associated colorectal cancer through HIF-1α regulation
- (2016) Jun Han et al. Oncology Letters
- TGF-β Signaling in Bone Remodeling and Osteosarcoma Progression
- (2016) Audrey Lamora et al. Journal of Clinical Medicine
- CXCR1 knockdown improves the sensitivity of osteosarcoma to cisplatin
- (2015) Xiu-guo Han et al. CANCER LETTERS
- Hypoxia Drives Breast Tumor Malignancy through a TET–TNFα–p38–MAPK Signaling Axis
- (2015) Min-Zu Wu et al. CANCER RESEARCH
- lnflammation-induced epigenetic switches in cancer
- (2015) Matjaz Rokavec et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Bone microenvironment signals in osteosarcoma development
- (2015) Arantzazu Alfranca et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Inhibition of IL-6 signaling significantly reduces primary tumor growth and recurrencies in orthotopic xenograft models of pancreatic cancer
- (2015) Freya A. Goumas et al. INTERNATIONAL JOURNAL OF CANCER
- Monocyte chemotactic protein-1 promotes the proliferation and invasion of osteosarcoma cells and upregulates the expression of AKT
- (2015) QUANCHI CHEN et al. Molecular Medicine Reports
- Regulation of c-Myc expression by the histone demethylase JMJD1A is essential for prostate cancer cell growth and survival
- (2015) L Fan et al. ONCOGENE
- Versatile functions for IL-6 in metabolism and cancer
- (2015) Jan Mauer et al. TRENDS IN IMMUNOLOGY
- Expression of platelet-derived growth factor BB, erythropoietin and erythropoietin receptor in canine and feline osteosarcoma
- (2015) F.R.L. Meyer et al. VETERINARY JOURNAL
- Interleukin 6 Receptor Is an Independent Prognostic Factor and a Potential Therapeutic Target of Ovarian Cancer
- (2015) Aki Isobe et al. PLoS One
- The IL-6/JAK/Stat3 Feed-Forward Loop Drives Tumorigenesis and Metastasis
- (2015) Qing Chang et al. NEOPLASIA
- Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions
- (2014) Hao Wu et al. CELL
- Bisphosphonates Inhibit Osteosarcoma-Mediated Osteolysis Via Attenuation of Tumor Expression of MCP-1 and RANKL
- (2014) Tetsuro Ohba et al. JOURNAL OF BONE AND MINERAL RESEARCH
- The Hypoxia-Inducible Epigenetic Regulators Jmjd1a and G9a Provide a Mechanistic Link between Angiogenesis and Tumor Growth
- (2014) J. Ueda et al. MOLECULAR AND CELLULAR BIOLOGY
- Autocrine VEGF/VEGFR1 Signaling in a Subpopulation of Cells Associates with Aggressive Osteosarcoma
- (2014) Tetsuro Ohba et al. MOLECULAR CANCER RESEARCH
- The Secreted Protein ANGPTL2 Promotes Metastasis of Osteosarcoma Cells Through Integrin 5 1, p38 MAPK, and Matrix Metalloproteinases
- (2014) H. Odagiri et al. Science Signaling
- Diverse roles of ANGPTL2 in physiology and pathophysiology
- (2014) Tsuyoshi Kadomatsu et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- TET1-Mediated Hydroxymethylation Facilitates Hypoxic Gene Induction in Neuroblastoma
- (2014) Christopher J. Mariani et al. Cell Reports
- Interplay between the Cancer Genome and Epigenome
- (2013) Hui Shen et al. CELL
- JMJD2B Promotes Epithelial-Mesenchymal Transition by Cooperating with -Catenin and Enhances Gastric Cancer Metastasis
- (2013) L. Zhao et al. CLINICAL CANCER RESEARCH
- Inflammatory chemokines and metastasis—tracing the accessory
- (2013) L Borsig et al. ONCOGENE
- A Molecular Clock Regulates Angiopoietin-Like Protein 2 Expression
- (2013) Tsuyoshi Kadomatsu et al. PLoS One
- Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
- (2012) Douglas Hanahan et al. CANCER CELL
- Cancer Genetics and Epigenetics: Two Sides of the Same Coin?
- (2012) Jueng Soo You et al. CANCER CELL
- STAT3 activation by IL-6 from mesenchymal stem cells promotes the proliferation and metastasis of osteosarcoma
- (2012) Bing Tu et al. CANCER LETTERS
- IL-6 promotes ICAM-1 expression and cell motility in human osteosarcoma
- (2012) Yu-Min Lin et al. CANCER LETTERS
- Cancer metabolism: Key players in metabolic reprogramming
- (2012) Tomoyoshi Soga CANCER SCIENCE
- STAT3 can serve as a hit in the process of malignant transformation of primary cells
- (2012) M Demaria et al. CELL DEATH AND DIFFERENTIATION
- Identification of osteosarcoma driver genes by integrative analysis of copy number and gene expression data
- (2012) Marieke L. Kuijjer et al. GENES CHROMOSOMES & CANCER
- Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact
- (2012) Joshua C. Black et al. MOLECULAR CELL
- Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation
- (2012) H Yang et al. ONCOGENE
- Quantitative Sequencing of 5-Methylcytosine and 5-Hydroxymethylcytosine at Single-Base Resolution
- (2012) M. J. Booth et al. SCIENCE
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- DNA methylation: TET proteins—guardians of CpG islands?
- (2011) Kristine Williams et al. EMBO REPORTS
- Uncovering the role of 5-hydroxymethylcytosine in the epigenome
- (2011) Miguel R. Branco et al. NATURE REVIEWS GENETICS
- The Expression of Histone Demethylase JMJD1A in Renal Cell Carcinoma
- (2011) X. GUO et al. NEOPLASMA
- Human mesenchymal stem cells promote growth of osteosarcoma: Involvement of interleukin-6 in the interaction between human mesenchymal stem cells and Saos-2
- (2010) Zhen-Yu Bian et al. CANCER SCIENCE
- c-MYC overexpression with loss of Ink4a/Arf transforms bone marrow stromal cells into osteosarcoma accompanied by loss of adipogenesis
- (2010) T Shimizu et al. ONCOGENE
- HIF-1: upstream and downstream of cancer metabolism
- (2009) Gregg L Semenza CURRENT OPINION IN GENETICS & DEVELOPMENT
- Methylation status of a single CpG site in theIL6promoter is related toIL6messenger RNA levels and rheumatoid arthritis
- (2008) Christoper J. Nile et al. ARTHRITIS AND RHEUMATISM
- Cancer Cell Metabolism: Warburg and Beyond
- (2008) Peggy P. Hsu et al. CELL
- The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
- (2008) Ralph J. DeBerardinis et al. Cell Metabolism
- The Interleukin-8 Pathway in Cancer
- (2008) D. J.J. Waugh et al. CLINICAL CANCER RESEARCH
- Early development of human hematopoietic and acquired immune systems in new born NOD/Scid/Jak3null mice intrahepatic engrafted with cord blood-derived CD34+ cells
- (2008) Seiji Okada et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Cancer-related inflammation
- (2008) Alberto Mantovani et al. NATURE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now