Regulation of c-Myc expression by the histone demethylase JMJD1A is essential for prostate cancer cell growth and survival

HUWE1 Ubiquitylates and Degrades the RAC Activator TIAM1 Promoting Cell-Cell Adhesion Disassembly, Migration, and Invasion

(2015) Lynsey Vaughan et al.   Cell Reports

The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1

(2015) Andrew E. Tee et al.   Oncotarget

HUWE1 interacts with BRCA1 and promotes its degradation in the ubiquitin–proteasome pathway

(2014) Xiaozhen Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Gene signatures ESC, MYC and ERG-fusion are early markers of a potentially dangerous subtype of prostate cancer

(2014) Morten Beck Rye et al.   BMC Medical Genomics

RETRACTED ARTICLE: ChIP-seq analysis of androgen receptor in LNCaP cell line

(2014) Sifeng Tao et al.   MOLECULAR BIOLOGY REPORTS

RapidCaP, a Novel GEM Model for Metastatic Prostate Cancer Analysis and Therapy, Reveals Myc as a Driver of Pten-Mutant Metastasis

(2014) H. Cho et al.   Cancer Discovery

The histone demethylase JMJD1A regulates adrenomedullin-mediated cell proliferation in hepatocellular carcinoma under hypoxia

(2013) Seong-Joon Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of Histone Demethylase JMJD1A Improves Anti-Angiogenic Therapy and Reduces Tumor-Associated Macrophages

(2013) T. Osawa et al.   CANCER RESEARCH

A Road Map to Comprehensive Androgen Receptor Axis Targeting for Castration-Resistant Prostate Cancer

(2013) N. Mitsiades   CANCER RESEARCH

RNAi-Mediated Silencing of Myc Transcription Inhibits Stem-like Cell Maintenance and Tumorigenicity in Prostate Cancer

(2013) G. Civenni et al.   CANCER RESEARCH

Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15

(2013) S. Inoue et al.   GENES & DEVELOPMENT

Control of Histone H3 Lysine 9 (H3K9) Methylation State via Cooperative Two-step Demethylation by Jumonji Domain Containing 1A (JMJD1A) Homodimer

(2013) Satoshi Goda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The histone demethylase KDM3A is a microRNA-22-regulated tumor promoter in Ewing Sarcoma

(2013) J K Parrish et al.   ONCOGENE

Androgen Receptor Promotes Ligand-Independent Prostate Cancer Progression through c-Myc Upregulation

(2013) Lina Gao et al.   PLoS One

Epigenetic Regulation of Mouse Sex Determination by the Histone Demethylase Jmjd1a

(2013) S. Kuroki et al.   SCIENCE

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The Androgen Receptor Induces a Distinct Transcriptional Program in Castration-Resistant Prostate Cancer in Man

(2012) Naomi L. Sharma et al.   CANCER CELL

B-Raf Activation Cooperates with PTEN Loss to Drive c-Myc Expression in Advanced Prostate Cancer

(2012) J. Wang et al.   CANCER RESEARCH

MYC on the Path to Cancer

(2012) Chi V. Dang   CELL

Dynamic Change of Chromatin Conformation in Response to Hypoxia Enhances the Expression of GLUT3 (SLC2A3) by Cooperative Interaction of Hypoxia-Inducible Factor 1 and KDM3A

(2012) I. Mimura et al.   MOLECULAR AND CELLULAR BIOLOGY

The mutational landscape of lethal castration-resistant prostate cancer

(2012) Catherine S. Grasso et al.   NATURE

Androgen Receptor Gene Expression in Prostate Cancer Is Directly Suppressed by the Androgen Receptor Through Recruitment of Lysine-Specific Demethylase 1

(2011) Changmeng Cai et al.   CANCER CELL

A mouse model of heterogeneous, c-MYC-initiated prostate cancer with loss of Pten and p53

(2011) J Kim et al.   ONCOGENE

Tumour-initiating stem-like cells in human prostate cancer exhibit increased NF-κB signalling

(2011) Vinagolu K. Rajasekhar et al.   Nature Communications

Siah2-Dependent Concerted Activity of HIF and FoxA2 Regulates Formation of Neuroendocrine Phenotype and Neuroendocrine Prostate Tumors

(2010) Jianfei Qi et al.   CANCER CELL

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

Long-range enhancers on 8q24 regulate c-Myc

(2010) J. Sotelo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overexpression of C-MYC oncogene in prostate cancer predicts biochemical recurrence

(2010) D Hawksworth et al.   PROSTATE CANCER AND PROSTATIC DISEASES

Somatic Single Hits Inactivate the X-Linked Tumor Suppressor FOXP3 in the Prostate

(2009) Lizhong Wang et al.   CANCER CELL

Regulation of the Histone Demethylase JMJD1A by Hypoxia-Inducible Factor 1  Enhances Hypoxic Gene Expression and Tumor Growth

(2009) A. J. Krieg et al.   MOLECULAR AND CELLULAR BIOLOGY

Role of Jhdm2a in regulating metabolic gene expression and obesity resistance

(2009) Keisuke Tateishi et al.   NATURE

Activator Protein-1 Transcription Factors Are Associated with Progression and Recurrence of Prostate Cancer

(2008) X. Ouyang et al.   CANCER RESEARCH

Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis

(2008) Bora Gurel et al.   MODERN PATHOLOGY

The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein

(2008) Xudong Zhao et al.   NATURE CELL BIOLOGY