- Home
- Publications
- Publication Search
- Publication Details
Title
Intermittent metabolic switching, neuroplasticity and brain health
Authors
Keywords
-
Journal
NATURE REVIEWS NEUROSCIENCE
Volume 19, Issue 2, Pages 63-80
Publisher
Springer Nature
Online
2018-01-11
DOI
10.1038/nrn.2017.156
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The ketogenic diet metabolite beta-hydroxybutyrate (β-HB) reduces incidence of seizure-like activity (SLA) in a K atp - and GABA b -dependent manner in a whole-animal Drosophila melanogaster model
- (2017) Jinglu Li et al. EPILEPSY RESEARCH
- A 3-Month Aerobic Training Program Improves Brain Energy Metabolism in Mild Alzheimer’s Disease: Preliminary Results from a Neuroimaging Study
- (2017) Christian-Alexandre Castellano et al. JOURNAL OF ALZHEIMERS DISEASE
- Future life expectancy in 35 industrialised countries: projections with a Bayesian model ensemble
- (2017) Vasilis Kontis et al. LANCET
- Neurological consequences of obesity
- (2017) Phillipe D O'Brien et al. LANCET NEUROLOGY
- Ketogenic diet versus gluten free casein free diet in autistic children: a case-control study
- (2017) Omnia El-Rashidy et al. METABOLIC BRAIN DISEASE
- Ketone Bodies as Anti-Seizure Agents
- (2017) Timothy A. Simeone et al. NEUROCHEMICAL RESEARCH
- Contribution of neuroinflammation and immunity to brain aging and the mitigating effects of physical and cognitive interventions
- (2017) Svetlana Di Benedetto et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Mitochondrial Sirtuins and Molecular Mechanisms of Aging
- (2017) Robert A.H. van de Ven et al. TRENDS IN MOLECULAR MEDICINE
- Adaptive Capacity: An Evolutionary Neuroscience Model Linking Exercise, Cognition, and Brain Health
- (2017) David A. Raichlen et al. TRENDS IN NEUROSCIENCES
- Mitophagy and Alzheimer’s Disease: Cellular and Molecular Mechanisms
- (2017) Jesse S. Kerr et al. TRENDS IN NEUROSCIENCES
- Parkinson disease
- (2017) Werner Poewe et al. Nature Reviews Disease Primers
- Exercise as a pro-cognitive, pro-neurogenic and anti-inflammatory intervention in transgenic mouse models of Alzheimer’s disease
- (2016) Sinéad M. Ryan et al. AGEING RESEARCH REVIEWS
- The effect of physical activity on cognitive function in patients with dementia: A meta-analysis of randomized control trials
- (2016) C. Groot et al. AGEING RESEARCH REVIEWS
- The more the better? A meta-analysis on effects of combined cognitive and physical intervention on cognition in healthy older adults
- (2016) Xinyi Zhu et al. AGEING RESEARCH REVIEWS
- Caloric restriction preserves memory and reduces anxiety of aging mice with early enhancement of neurovascular functions
- (2016) Ishita Parikh et al. Aging-US
- PGC-1α/ERRα-Sirt3 Pathway Regulates DAergic Neuronal Death by Directly Deacetylating SOD2 and ATP Synthase β
- (2016) Xuefei Zhang et al. ANTIOXIDANTS & REDOX SIGNALING
- Unravelling the mechanisms regulating muscle mitochondrial biogenesis
- (2016) D. A. Hood et al. BIOCHEMICAL JOURNAL
- Mitochondrial SIRT3 Mediates Adaptive Responses of Neurons to Exercise and Metabolic and Excitatory Challenges
- (2016) Aiwu Cheng et al. Cell Metabolism
- Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function
- (2016) Hyo Youl Moon et al. Cell Metabolism
- Novel ketone diet enhances physical and cognitive performance
- (2016) Andrew J. Murray et al. FASEB JOURNAL
- Mediators of Physical Activity on Neurocognitive Function: A Review at Multiple Levels of Analysis
- (2016) Chelsea M. Stillman et al. Frontiers in Human Neuroscience
- Inverse relationship between brain glucose and ketone metabolism in adults during short-term moderate dietary ketosis: A dual tracer quantitative positron emission tomography study
- (2016) Alexandre Courchesne-Loyer et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- 3-Hydroxybutyrate regulates energy metabolism and induces BDNF expression in cerebral cortical neurons
- (2016) Krisztina Marosi et al. JOURNAL OF NEUROCHEMISTRY
- Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease
- (2016) J. A. Bayliss et al. JOURNAL OF NEUROSCIENCE
- Homeostasis Meets Motivation in the Battle to Control Food Intake
- (2016) Carrie R. Ferrario et al. JOURNAL OF NEUROSCIENCE
- Physiological adaptations to interval training and the role of exercise intensity
- (2016) Martin J. MacInnis et al. JOURNAL OF PHYSIOLOGY-LONDON
- Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation
- (2016) Ángel Chamorro et al. LANCET NEUROLOGY
- The best medicine? The influence of physical activity and inactivity on Parkinson's disease
- (2016) Sara C. LaHue et al. MOVEMENT DISORDERS
- Running rewires the neuronal network of adult-born dentate granule cells
- (2016) Carmen Vivar et al. NEUROIMAGE
- A Postsynaptic AMPK→p21-Activated Kinase Pathway Drives Fasting-Induced Synaptic Plasticity in AgRP Neurons
- (2016) Dong Kong et al. NEURON
- Mechanisms of Action of Antiseizure Drugs and the Ketogenic Diet
- (2016) Michael A. Rogawski et al. Cold Spring Harbor Perspectives in Medicine
- Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate
- (2016) Sama F Sleiman et al. eLife
- Exercise, Physical Activity, and Sedentary Behavior in the Treatment of Depression: Broadening the Scientific Perspectives and Clinical Opportunities
- (2016) Mats Hallgren et al. Frontiers in Psychiatry
- Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1α in skeletal muscle
- (2016) Orsolya M. Palacios et al. Aging-US
- Lifelong brain health is a lifelong challenge: From evolutionary principles to empirical evidence
- (2015) Mark P. Mattson AGEING RESEARCH REVIEWS
- Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population-based perspective
- (2015) Matthew Baumgart et al. Alzheimers & Dementia
- Evolutionary and functional perspectives on signaling from neuronal surface to nucleus
- (2015) Samuel M. Cohen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan
- (2015) Sebastian Brandhorst et al. Cell Metabolism
- Effects of Physical Exercise on Depressive Symptoms and Biomarkers in Depression
- (2015) Trevor Archer et al. CNS & Neurological Disorders-Drug Targets
- Ghrelin is required for dietary restriction-induced enhancement of hippocampal neurogenesis: lessons from ghrelin knockout mice
- (2015) Yumi Kim et al. ENDOCRINE JOURNAL
- Anxiolytic-Like Effects of Increased Ghrelin Receptor Signaling in the Amygdala
- (2015) Morten Jensen et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Exercise training-induced bradycardia: evidence for enhanced parasympathetic regulation without changes in intrinsic sinoatrial node function
- (2015) George E. Billman et al. JOURNAL OF APPLIED PHYSIOLOGY
- Sirtuin 3 Mediates Neuroprotection of Ketones against Ischemic Stroke
- (2015) Junxiang Yin et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Dysregulation of Mammalian Target of Rapamycin Signaling in Mouse Models of Autism
- (2015) K. M. Huber et al. JOURNAL OF NEUROSCIENCE
- Parkinson's disease and intensive exercise therapy – a systematic review and meta-analysis of randomized controlled trials
- (2015) Anders Uhrbrand et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial
- (2015) Tiia Ngandu et al. LANCET
- Enhanced Glutamatergic Synaptic Plasticity in the Hippocampal CA1 Field of Food-Restricted Rats: Involvement of CB1 Receptors
- (2015) Giuseppe Talani et al. NEUROPSYCHOPHARMACOLOGY
- AMPK Signaling in the Dorsal Hippocampus Negatively Regulates Contextual Fear Memory Formation
- (2015) Ying Han et al. NEUROPSYCHOPHARMACOLOGY
- Models and mechanisms for hippocampal dysfunction in obesity and diabetes
- (2015) A.M. Stranahan NEUROSCIENCE
- mTOR in Brain Physiology and Pathologies
- (2015) Joël Bockaert et al. PHYSIOLOGICAL REVIEWS
- Expanding roles for AMPK in skeletal muscle plasticity
- (2015) Rémi Mounier et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Calorie Restriction Suppresses Age-Dependent Hippocampal Transcriptional Signatures
- (2015) Marissa J. Schafer et al. PLoS One
- Interleukin-6 contributes to early fasting-induced free fatty acid mobilization in mice
- (2014) Stephan Wueest et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Fasting: Molecular Mechanisms and Clinical Applications
- (2014) Valter D. Longo et al. Cell Metabolism
- Evidence that BDNF regulates heart rate by a mechanism involving increased brainstem parasympathetic neuron excitability
- (2014) Ruiqian Wan et al. JOURNAL OF NEUROCHEMISTRY
- AMPK agonist AICAR improves cognition and motor coordination in young and aged mice
- (2014) T. Kobilo et al. LEARNING & MEMORY
- The 5-HT3 receptor is essential for exercise-induced hippocampal neurogenesis and antidepressant effects
- (2014) M Kondo et al. MOLECULAR PSYCHIATRY
- Effects of exercise on mitochondrial function, neuroplasticity and anxio-depressive behavior of mice
- (2014) A.S. Aguiar et al. NEUROSCIENCE
- Exercise-Induced Neuroprotection of Hippocampus in APP/PS1 Transgenic Mice via Upregulation of Mitochondrial 8-Oxoguanine DNA Glycosylase
- (2014) Hai Bo et al. Oxidative Medicine and Cellular Longevity
- Novel mechanistic insights into treadmill exercise based rescue of social defeat-induced anxiety-like behavior and memory impairment in rats
- (2014) Gaurav Patki et al. PHYSIOLOGY & BEHAVIOR
- The β-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophages
- (2014) Mahbubur Rahman et al. Nature Communications
- Superior pattern processing is the essence of the evolved human brain
- (2014) Mark P. Mattson Frontiers in Neuroscience
- The neuropathology of obesity: insights from human disease
- (2013) Edward B. Lee et al. ACTA NEUROPATHOLOGICA
- Metabolite and transcriptome analysis during fasting suggest a role for the p53-Ddit4 axis in major metabolic tissues
- (2013) Michael Schupp et al. BMC GENOMICS
- The effect of intermittent energy and carbohydrate restriction v. daily energy restriction on weight loss and metabolic disease risk markers in overweight women
- (2013) Michelle Harvie et al. BRITISH JOURNAL OF NUTRITION
- Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway
- (2013) Christiane D. Wrann et al. Cell Metabolism
- Association of brain-derived neurotrophic factor (BDNF) haploinsufficiency with lower adaptive behaviour and reduced cognitive functioning in WAGR/11p13 deletion syndrome
- (2013) Joan C. Han et al. CORTEX
- mTOR is a key modulator of ageing and age-related disease
- (2013) Simon C. Johnson et al. NATURE
- The role of autophagy in neurodegenerative disease
- (2013) Ralph A Nixon NATURE MEDICINE
- BDNF and Exercise Enhance Neuronal DNA Repair by Stimulating CREB-Mediated Production of Apurinic/Apyrimidinic Endonuclease 1
- (2013) Jenq-Lin Yang et al. NEUROMOLECULAR MEDICINE
- AMPK activation regulates neuronal structure in developing hippocampal neurons
- (2013) S. Ramamurthy et al. NEUROSCIENCE
- Serotonin and beyond: therapeutics for major depression
- (2013) P. Blier et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Ketogenic Diet Improves Core Symptoms of Autism in BTBR Mice
- (2013) David N. Ruskin et al. PLoS One
- Fasting Launches CRTC to Facilitate Long-Term Memory Formation in Drosophila
- (2013) Y. Hirano et al. SCIENCE
- BDNF mediates adaptive brain and body responses to energetic challenges
- (2013) Krisztina Marosi et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Ketone bodies as signaling metabolites
- (2013) John C. Newman et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Hypothalamic clocks and rhythms in feeding behaviour
- (2013) David A. Bechtold et al. TRENDS IN NEUROSCIENCES
- Burden of Depressive Disorders by Country, Sex, Age, and Year: Findings from the Global Burden of Disease Study 2010
- (2013) Alize J. Ferrari et al. PLOS MEDICINE
- Metabolic disturbances connecting obesity and depression
- (2013) Cecile Hryhorczuk et al. Frontiers in Neuroscience
- Molecular and neural bases underlying roles of BDNF in the control of body weight
- (2013) Filip Vanevski et al. Frontiers in Neuroscience
- Exercise induces autophagy in peripheral tissues and in the brain
- (2012) Congcong He et al. Autophagy
- Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet
- (2012) Megumi Hatori et al. Cell Metabolism
- Energy Intake and Exercise as Determinants of Brain Health and Vulnerability to Injury and Disease
- (2012) Mark P. Mattson Cell Metabolism
- Genetic architecture in autism spectrum disorder
- (2012) Bernie Devlin et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Intermittent fasting: A “new” historical strategy for controlling seizures?
- (2012) Adam L. Hartman et al. EPILEPSY RESEARCH
- Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer's disease
- (2012) Misha Zilberter et al. JOURNAL OF NEUROCHEMISTRY
- Multiple Roles for Mammalian Target of Rapamycin Signaling in Both Glutamatergic and GABAergic Synaptic Transmission
- (2012) M. C. Weston et al. JOURNAL OF NEUROSCIENCE
- Neuronal Stimulation Induces Autophagy in Hippocampal Neurons That Is Involved in AMPA Receptor Degradation after Chemical Long-Term Depression
- (2012) M. Shehata et al. JOURNAL OF NEUROSCIENCE
- Muscles, exercise and obesity: skeletal muscle as a secretory organ
- (2012) Bente K. Pedersen et al. Nature Reviews Endocrinology
- Dietary energy intake modifies brainstem autonomic dysfunction caused by mutant α-synuclein
- (2012) Kathleen J. Griffioen et al. NEUROBIOLOGY OF AGING
- A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease
- (2012) Yoshihiro Kashiwaya et al. NEUROBIOLOGY OF AGING
- Regulation of Presynaptic Neurotransmission by Macroautophagy
- (2012) Daniela Hernandez et al. NEURON
- Long-term exercise treatment reduces oxidative stress in the hippocampus of aging rats
- (2012) K. Marosi et al. NEUROSCIENCE
- Exercise Does Not Protect against MPTP-Induced Neurotoxicity in BDNF Happloinsufficent Mice
- (2012) Kim M. Gerecke et al. PLoS One
- Suppression of Oxidative Stress by -Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor
- (2012) T. Shimazu et al. SCIENCE
- Involvement of PGC-1α in the formation and maintenance of neuronal dendritic spines
- (2012) Aiwu Cheng et al. Nature Communications
- Monosynaptic inputs to new neurons in the dentate gyrus
- (2012) Carmen Vivar et al. Nature Communications
- Resilience to Chronic Stress Is Mediated by Hippocampal Brain-Derived Neurotrophic Factor
- (2011) D. Taliaz et al. JOURNAL OF NEUROSCIENCE
- Intermittent Fasting Improves Functional Recovery after Rat Thoracic Contusion Spinal Cord Injury
- (2011) Mi-ae Jeong et al. JOURNAL OF NEUROTRAUMA
- Memory of fearful events: the role of fibroblast growth factor-2 in fear acquisition and extinction
- (2011) B.M. Graham et al. NEUROSCIENCE
- A role for neuronal cAMP responsive-element binding (CREB)-1 in brain responses to calorie restriction
- (2011) S. Fusco et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metabolic-cognitive syndrome: A cross-talk between metabolic syndrome and Alzheimer's disease
- (2010) Vincenza Frisardi et al. AGEING RESEARCH REVIEWS
- Short-term fasting induces profound neuronal autophagy
- (2010) Mehrdad Alirezaei et al. Autophagy
- The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women
- (2010) M N Harvie et al. INTERNATIONAL JOURNAL OF OBESITY
- Exercise and Fasting Activate Growth Hormone-Dependent Myocellular Signal Transducer and Activator of Transcription-5b Phosphorylation and Insulin-Like Growth Factor-I Messenger Ribonucleic Acid Expression in Humans
- (2010) Mikkel H. Vendelbo et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Expression and Functions of Fibroblast Growth Factor 2 (FGF-2) in Hippocampal Formation
- (2010) Sabrina Zechel et al. NEUROSCIENTIST
- The extra-hypothalamic actions of ghrelin on neuronal function
- (2010) Zane B. Andrews TRENDS IN NEUROSCIENCES
- PET study of 11C-acetoacetate kinetics in rat brain during dietary treatments affecting ketosis
- (2009) M'hamed Bentourkia et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Age and energy intake interact to modify cell stress pathways and stroke outcome
- (2009) Thiruma V. Arumugam et al. ANNALS OF NEUROLOGY
- Impaired hippocampus-dependent and -independent learning in IL-6 deficient mice
- (2009) Paul Christian Baier et al. BEHAVIOURAL BRAIN RESEARCH
- Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice
- (2009) Alexis M. Stranahan et al. HIPPOCAMPUS
- Reviews: Mechanisms Mediating Brain Plasticity: IGF1 and Adult Hippocampal Neurogenesis
- (2009) María LLorens-Martín et al. NEUROSCIENTIST
- Peripheral insulin-like growth factor-I produces antidepressant-like behavior and contributes to the effect of exercise
- (2008) Catharine H. Duman et al. BEHAVIOURAL BRAIN RESEARCH
- Why Eating Less Keeps Mitochondria Working in Aged Skeletal Muscle
- (2008) Russell T. Hepple EXERCISE AND SPORT SCIENCES REVIEWS
- Dietary restriction started after spinal cord injury improves functional recovery
- (2008) Ward T. Plunet et al. EXPERIMENTAL NEUROLOGY
- Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats
- (2008) Alexis M. Stranahan et al. HIPPOCAMPUS
- Fasting is neuroprotective following traumatic brain injury
- (2008) Laurie M. Davis et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons
- (2008) Alexis M Stranahan et al. NATURE NEUROSCIENCE
- Removal of FKBP12 Enhances mTOR-Raptor Interactions, LTP, Memory, and Perseverative/Repetitive Behavior
- (2008) Charles A. Hoeffer et al. NEURON
- TrkB Regulates Hippocampal Neurogenesis and Governs Sensitivity to Antidepressive Treatment
- (2008) Yun Li et al. NEURON
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started