Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate

An Isochemogenic Set of Inhibitors To Define the Therapeutic Potential of Histone Deacetylases in β-Cell Protection

(2015) Florence F. Wagner et al.   ACS Chemical Biology

Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry

(2015) Mark P. Jedrychowski et al.   Cell Metabolism

Up-regulation of c-Jun NH2-terminal kinase-interacting protein 3 (JIP3) contributes to BDNF-enhanced neurotransmitter release

(2015) Bing Chen et al.   JOURNAL OF NEUROCHEMISTRY

Irisin – a myth rather than an exercise-inducible myokine

(2015) Elke Albrecht et al.   Scientific Reports

β-hydroxybutyrate: Much more than a metabolite

(2014) John C. Newman et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Acute exercise increases brain region-specific expression of MCT1, MCT2, MCT4, GLUT1, and COX IV proteins

(2014) Masaki Takimoto et al.   JOURNAL OF APPLIED PHYSIOLOGY

Selective HDAC Inhibition for the Disruption of Latent HIV-1 Infection

(2014) Kirston M. Barton et al.   PLoS One

What's on TV? Detecting age-related neurodegenerative eye disease using eye movement scanpaths

(2014) David P. Crabb et al.   Frontiers in Aging Neuroscience

Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway

(2013) Christiane D. Wrann et al.   Cell Metabolism

BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases

(2013) Bai Lu et al.   NATURE REVIEWS NEUROSCIENCE

Differential regulation of Bdnf expression in cortical neurons by class-selective histone deacetylase inhibitors

(2013) Indrek Koppel et al.   NEUROPHARMACOLOGY

Running throughout middle-age improves memory function, hippocampal neurogenesis, and BDNF levels in female C57BL/6J mice

(2012) Michael W. Marlatt et al.   Developmental Neurobiology

Run for your life

(2012) Timothy Noakes et al.   NATURE

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

Suppression of Oxidative Stress by  -Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor

(2012) T. Shimazu et al.   SCIENCE

Identification of cis-Elements and Transcription Factors Regulating Neuronal Activity-Dependent Transcription of Human BDNF Gene

(2011) P. Pruunsild et al.   JOURNAL OF NEUROSCIENCE

Short bouts of mild-intensity physical exercise improve spatial learning and memory in aging rats: Involvement of hippocampal plasticity via AKT, CREB and BDNF signaling

(2011) Aderbal S. Aguiar et al.   MECHANISMS OF AGEING AND DEVELOPMENT

2-Deoxy-D-Glucose Treatment Induces Ketogenesis, Sustains Mitochondrial Function, and Reduces Pathology in Female Mouse Model of Alzheimer's Disease

(2011) Jia Yao et al.   PLoS One

D-β-Hydroxybutyrate Is Protective in Mouse Models of Huntington's Disease

(2011) Soyeon Lim et al.   PLoS One

Rapid Communication: Oxidative Stress Induces Apoptosis in Embryonic Cortical Neurons

(2010) Rajiv R. Ratan et al.   JOURNAL OF NEUROCHEMISTRY

Evidence for a release of brain-derived neurotrophic factor from the brain during exercise

(2009) Peter Rasmussen et al.   EXPERIMENTAL PHYSIOLOGY

Exercise increases BDNF levels in the striatum and decreases depressive-like behavior in chronically stressed rats

(2009) Lelanie Marais et al.   METABOLIC BRAIN DISEASE

HDAC2 negatively regulates memory formation and synaptic plasticity

(2009) Ji-Song Guan et al.   NATURE

Brain-derived neurotrophic factor in neurodegenerative diseases

(2009) Chiara Zuccato et al.   Nature Reviews Neurology

The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies

(2008) Marwan Maalouf et al.   BRAIN RESEARCH REVIEWS

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

(2008) Michael Haberland et al.   NATURE REVIEWS GENETICS

A catabolic block does not sufficiently explain how 2-deoxy-D-glucose inhibits cell growth

(2008) M. Ralser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA