Dll1+ secretory progenitor cells revert to stem cells upon crypt damage

The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers

(2012) Javier Muñoz et al.   EMBO JOURNAL

Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes

(2011) Arnout G Schepers et al.   EMBO JOURNAL

Dll1- and Dll4-Mediated Notch Signaling Are Required for Homeostasis of Intestinal Stem Cells

(2011) Luca Pellegrinet et al.   GASTROENTEROLOGY

Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium

(2011) François Gerbe et al.   JOURNAL OF CELL BIOLOGY

Origin and maintenance of the intestinal cancer stem cell

(2011) Emma J. Davies et al.   MOLECULAR CARCINOGENESIS

A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable

(2011) Hua Tian et al.   NATURE

Single-molecule transcript counting of stem-cell markers in the mouse intestine

(2011) Shalev Itzkovitz et al.   NATURE CELL BIOLOGY

Delta1 Expression, Cell Cycle Exit, and Commitment to a Specific Secretory Fate Coincide within a Few Hours in the Mouse Intestinal Stem Cell System

(2011) Despina Stamataki et al.   PLoS One

The Role of Colorectal Cancer Stem Cells in Metastatic Disease and Therapeutic Response

(2011) Eric C. Anderson et al.   Cancers

Sorting mouse jejunal epithelial cells with CD24 yields a population with characteristics of intestinal stem cells

(2010) Richard J. von Furstenberg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

(2010) Hugo J. Snippert et al.   CELL

Cell Lineage metastability in Gfi1-deficient mouse intestinal epithelium

(2010) Matthew Bjerknes et al.   DEVELOPMENTAL BIOLOGY

Therapeutic antibody targeting of individual Notch receptors

(2010) Yan Wu et al.   NATURE

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

(2010) Toshiro Sato et al.   NATURE

Delivering the Lateral Inhibition Punchline: It's All About the Timing

(2010) J. D. Axelrod   Science Signaling

Intestinal stem cells lacking the Math1 tumour suppressor are refractory to Notch inhibitors

(2010) Johan H. van Es et al.   Nature Communications

SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells

(2009) Taeko K. Noah et al.   EXPERIMENTAL CELL RESEARCH

The Ets-Domain Transcription Factor Spdef Promotes Maturation of Goblet and Paneth Cells in the Intestinal Epithelium

(2009) Alex Gregorieff et al.   GASTROENTEROLOGY

OLFM4 Is a Robust Marker for Stem Cells in Human Intestine and Marks a Subset of Colorectal Cancer Cells

(2009) Laurens G. van der Flier et al.   GASTROENTEROLOGY

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2

(2008) Orbicia Riccio et al.   EMBO REPORTS

Crypt stem cells as the cells-of-origin of intestinal cancer

(2008) Nick Barker et al.   NATURE

Bmi1 is expressed in vivo in intestinal stem cells

(2008) Eugenio Sangiorgi et al.   NATURE GENETICS

Imaging individual mRNA molecules using multiple singly labeled probes

(2008) Arjun Raj et al.   NATURE METHODS