Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases

Variants at HLA-A , HLA-C , and HLA-DQB1 Confer Risk of Psoriasis Vulgaris in Japanese

(2018) Jun Hirata et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

MendelianRandomization: an R package for performing Mendelian randomization analyses using summarized data

(2017) Olena O Yavorska et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Overview of the BioBank Japan Project: Study design and profile

(2017) Akiko Nagai et al.   JOURNAL OF EPIDEMIOLOGY

Cross-sectional analysis of BioBank Japan clinical data: A large cohort of 200,000 patients with 47 common diseases

(2017) Makoto Hirata et al.   JOURNAL OF EPIDEMIOLOGY

A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder

(2017) M Ikeda et al.   MOLECULAR PSYCHIATRY

Identification of six new genetic loci associated with atrial fibrillation in the Japanese population

(2017) Siew-Kee Low et al.   NATURE GENETICS

Genome-wide association study identifies 112 new loci for body mass index in the Japanese population

(2017) Masato Akiyama et al.   NATURE GENETICS

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

(2016) Jie Zheng et al.   BIOINFORMATICS

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease

(2016) William J. Astle et al.   CELL

Relation of serum uric acid to cardiovascular disease

(2016) Audrey H. Wu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Empirical estimation of genome-wide significance thresholds based on the 1000 Genomes Project data set

(2016) Masahiro Kanai et al.   JOURNAL OF HUMAN GENETICS

Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci

(2016) Chunyu Liu et al.   NATURE GENETICS

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

(2016) Praveen Surendran et al.   NATURE GENETICS

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

(2016) Georg B Ehret et al.   NATURE GENETICS

A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases

(2016) Buhm Han et al.   NATURE GENETICS

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

(2016) Cristian Pattaro et al.   Nature Communications

Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses

(2016) Nikhil K. Khankari et al.   PLOS MEDICINE

Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci

(2015) Gosia Trynka et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Functional SNP in BNC2 Is Associated with Adolescent Idiopathic Scoliosis

(2015) Yoji Ogura et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Integrative analysis of 111 reference human epigenomes

(2015) Anshul Kundaje et al.   NATURE

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

The impact of low-frequency and rare variants on lipid levels

(2015) Ida Surakka et al.   NATURE GENETICS

Construction of a population-specific HLA imputation reference panel and its application to Graves' disease risk in Japanese

(2015) Yukinori Okada et al.   NATURE GENETICS

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

(2015) Jimmy Z Liu et al.   NATURE GENETICS

Partitioning heritability by functional annotation using genome-wide association summary statistics

(2015) Hilary K Finucane et al.   NATURE GENETICS

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Efficient Bayesian mixed-model analysis increases association power in large cohorts

(2015) Po-Ru Loh et al.   NATURE GENETICS

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Serum total bilirubin concentrations are inversely associated with total white blood cell counts in an adult population

(2015) Wan-Ni Tsai et al.   ANNALS OF CLINICAL BIOCHEMISTRY

Genetic Variants Related to Height and Risk of Atrial Fibrillation

(2014) Michael A. Rosenberg et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

(2014) G. Davey Smith et al.   HUMAN MOLECULAR GENETICS

Bilirubin Possesses Powerful Immunomodulatory Activity and Suppresses Experimental Autoimmune Encephalomyelitis

(2014) Y. Liu et al.   JOURNAL OF IMMUNOLOGY

Defining the role of common variation in the genomic and biological architecture of adult human height

(2014) Andrew R Wood et al.   NATURE GENETICS

Concise Review: Evidence for CD34 as a Common Marker for Diverse Progenitors

(2014) Laura E. Sidney et al.   STEM CELLS

Genetics of rheumatoid arthritis contributes to biology and drug discovery

(2013) Yukinori Okada et al.   NATURE

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Value of Albumin–Globulin Ratio as a Predictor of All-Cause Mortality After Non-ST Elevation Myocardial Infarction

(2012) Basem Azab et al.   ANGIOLOGY

Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihood

(2012) S.H. Lee et al.   BIOINFORMATICS

Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population

(2012) Tomomitsu Hirota et al.   NATURE GENETICS

Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations

(2012) Yukinori Okada et al.   NATURE GENETICS

Abundant Pleiotropy in Human Complex Diseases and Traits

(2011) Shanya Sivakumaran et al.   AMERICAN JOURNAL OF HUMAN GENETICS

LocusZoom: regional visualization of genome-wide association scan results

(2010) R. J. Pruim et al.   BIOINFORMATICS

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

(2010) Yun Li et al.   GENETIC EPIDEMIOLOGY

Integrating common and rare genetic variation in diverse human populations

(2010)   NATURE

Genome-wide association study of hematological and biochemical traits in a Japanese population

(2010) Yoichiro Kamatani et al.   NATURE GENETICS

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

CD15 expression in human myeloid cell differentiation is regulated by sialidase activity

(2008) Samah Zeineb Gadhoum et al.   Nature Chemical Biology

Serum Total Bilirubin Level and Prevalent Lower-Extremity Peripheral Arterial Disease

(2007) Todd S. Perlstein et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY