The impact of low-frequency and rare variants on lipid levels

Gene expression analysis identifies global gene dosage sensitivity in cancer

(2015) Rudolf S N Fehrmann et al.   NATURE GENETICS

Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk

(2014) Oddgeir L Holmen et al.   NATURE GENETICS

Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

(2014) Julia Kozlitina et al.   NATURE GENETICS

Defining the role of common variation in the genomic and biological architecture of adult human height

(2014) Andrew R Wood et al.   NATURE GENETICS

TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content

(2014) H. Mahdessian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Re-sequencing Expands Our Understanding of the Phenotypic Impact of Variants at GWAS Loci

(2014) Susan K. Service et al.   PLoS Genetics

Heritability of metabolic syndrome traits in a large population-based sample

(2013) Jenny van Dongen et al.   JOURNAL OF LIPID RESEARCH

SMIM1 underlies the Vel blood group and influences red blood cell traits

(2013) Ana Cvejic et al.   NATURE GENETICS

Meta-analysis of gene-level tests for rare variant association

(2013) Dajiang J Liu et al.   NATURE GENETICS

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

RNAi–Based Functional Profiling of Loci from Blood Lipid Genome-Wide Association Studies Identifies Genes with Cholesterol-Regulatory Function

(2013) Peter Blattmann et al.   PLoS Genetics

Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes

(2012) A. Albrechtsen et al.   DIABETOLOGIA

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Rare and common variants: twenty arguments

(2012) Greg Gibson   NATURE REVIEWS GENETICS

Predicting the Functional Effect of Amino Acid Substitutions and Indels

(2012) Yongwook Choi et al.   PLoS One

Specific lipid recognition is a general feature of CD300 and TREM molecules

(2011) John P. Cannon et al.   IMMUNOGENETICS

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

GWAMA: software for genome-wide association meta-analysis

(2010) Reedik Mägi et al.   BMC BIOINFORMATICS

Meta-analysis of sex-specific genome-wide association studies

(2010) Reedik Magi et al.   GENETIC EPIDEMIOLOGY

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia

(2010) Christopher T Johansen et al.   NATURE GENETICS

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver

(2009) Nicola L. Beer et al.   HUMAN MOLECULAR GENETICS

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Nepmucin/CLM-9, an Ig domain-containing sialomucin in vascular endothelial cells, promotes lymphocyte transendothelial migration in vitro

(2008) Soojung Jin et al.   FEBS LETTERS