Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

Multivariable Mendelian Randomization: The Use of Pleiotropic Genetic Variants to Estimate Causal Effects

(2015) S. Burgess et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Meta-analysis of Correlated Traits via Summary Statistics from GWASs with an Application in Hypertension

(2015) Xiaofeng Zhu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Hypertension: Renin-Angiotensin-Aldosterone System Alterations

(2015) L. te Riet et al.   CIRCULATION RESEARCH

Integrative network analysis reveals molecular mechanisms of blood pressure regulation

(2015) T. Huan et al.   Molecular Systems Biology

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

Direct Estimates of the Genomic Contributions to Blood Pressure Heritability within a Population-Based Cohort (ARIC)

(2015) Elias Salfati et al.   PLoS One

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

(2015) Jie Huang et al.   Nature Communications

Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus

(2015) Anubha Mahajan et al.   PLoS Genetics

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Gene-Age Interactions in Blood Pressure Regulation: A Large-Scale Investigation with the CHARGE, Global BPgen, and ICBP Consortia

(2014) Jeannette Simino et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Gene-centric Meta-analysis in 87,736 Individuals of European Ancestry Identifies Multiple Blood-Pressure-Related Loci

(2014) Vinicius Tragante et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A new strategy for treating hypertension by blocking the activity of the brain renin–angiotensin system with aminopeptidase A inhibitors

(2014) Ji Gao et al.   CLINICAL SCIENCE

Heterozygous germline mutations in A2ML1 are associated with a disorder clinically related to Noonan syndrome

(2014) Lisenka ELM Vissers et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people

(2014) Eleni Rapsomaniki et al.   LANCET

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

(2014) Dan E Arking et al.   NATURE GENETICS

Defining the role of common variation in the genomic and biological architecture of adult human height

(2014) Andrew R Wood et al.   NATURE GENETICS

Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

(2014) Claudia Giambartolomei et al.   PLoS Genetics

Advances in Blood Pressure Genomics

(2013) Patricia B. Munroe et al.   CIRCULATION RESEARCH

rbm47, a novel RNA binding protein, regulates zebrafish head development

(2013) Rui Guan et al.   DEVELOPMENTAL DYNAMICS

Loci influencing blood pressure identified using a cardiovascular gene-centric array

(2013) Santhi K. Ganesh, Vinicius Tragante, Wei Guo, Yiran Guo, Matthew B. Lanktree, Erin N. Smith, Toby Johnson, Berta Almoguera Castillo, John Barnard, Jens Baumert, Yen-Pei Christy Chang, Clara C. Elbers, Martin Farrall, Mary E. Fischer, Nora Franceschini, Tom R. Gaunt, Johannes M.I.H. Gho, Christian Gieger, Yan Gong, Aaron Isaacs, Marcus E. Kleber, Irene Mateo Leach, Caitrin W. McDonough, Matthijs F.L. Meijs, Olle Mellander, Cliona M. Molony, Ilja M. Nolte, Sandosh Padmanabhan, Tom S. Price, Ramakrishnan Rajagopalan, Jonathan Shaffer, Sonia Shah, Haiqing Shen, Nicole Soranzo, Peter J. van der Most, Erik P.A. Van Iperen, Jessic A. Van Setten, Judith M. Vonk, Li Zhang, Amber L. Beitelshees, Gerald S. Berenson, Deepak L. Bhatt, Jolanda M.A. Boer, Eric Boerwinkle, Ben Burkley, Amber Burt, Aravinda Chakravarti, Wei Chen, Rhonda M. Cooper-DeHoff, Sean P. Curtis, Albert Dreisbach, David Duggan, Georg B. Ehret, Richard R. Fabsitz, Myriam Fornage, Ervin Fox, Clement E. Furlong, Ron T. Gansevoort, Marten H. Hofker, G. Kees Hovingh, Susan A. Kirkland, Kandice Kottke-Marchant, Abdullah Kutlar, Andrea Z. LaCroix, Taimour Y. Langaee, Yun R. Li, Honghuang Lin, Kiang Liu, Steffi Maiwald, Rainer Malik, Gurunathan Murugesan, Christopher Newton-Cheh, Jeffery R. O'Connell, N. Charlotte Onland-Moret, Willem H. Ouwehand et al.   HUMAN MOLECULAR GENETICS

Does accelerated reproductive aging underlie premenopausal risk for cardiovascular disease?

(2013) Maria E. Bleil et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Meta-analysis of gene-level tests for rare variant association

(2013) Dajiang J Liu et al.   NATURE GENETICS

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders

(2013) Marcel den Hoed et al.   NATURE GENETICS

Genome wide association study for plasma levels of natural anticoagulant inhibitors and protein C anticoagulant pathway: the MARTHA project

(2012) Tiphaine Oudot-Mellakh et al.   BRITISH JOURNAL OF HAEMATOLOGY

Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes

(2012) Sarah Brice Russo et al.   JOURNAL OF CLINICAL INVESTIGATION

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Stephen S Lim et al.   LANCET

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies

(2012) Matthew Traylor et al.   LANCET NEUROLOGY

Blood Pressure Loci Identified with a Gene-Centric Array

(2011) Toby Johnson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Rare-Variant Association Testing for Sequencing Data with the Sequence Kernel Association Test

(2011) Michael C. Wu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

(2011) Georg B. Ehret et al.   NATURE

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

(2011) Heribert Schunkert et al.   NATURE GENETICS

A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease

(2011) John F Peden et al.   NATURE GENETICS

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

(2011) Louise V Wain et al.   NATURE GENETICS

Serine-threonine kinase with-no-lysine 4 (WNK4) controls blood pressure via transient receptor potential canonical 3 (TRPC3) in the vasculature

(2011) H. W. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Architecture of Gene Regulatory Variation across Multiple Human Tissues: The MuTHER Study

(2011) Alexandra C. Nica et al.   PLoS Genetics

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Novel Associations of Multiple Genetic Loci With Plasma Levels of Factor VII, Factor VIII, and von Willebrand Factor

(2010) Nicholas L. Smith et al.   CIRCULATION

Association of Genome-Wide Variation With the Risk of Incident Heart Failure in Adults of European and African Ancestry

(2010) Nicholas L. Smith et al.   Circulation-Cardiovascular Genetics

Genetic Architecture of Ambulatory Blood Pressure in the General Population

(2010) Maciej Tomaszewski et al.   HYPERTENSION

Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits

(2010) Ayellet V. Segrè et al.   PLoS Genetics

Common vs. rare allele hypotheses for complex diseases

(2009) Nicholas J Schork et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Genetic Variants Associated With Cardiac Structure and Function

(2009) Ramachandran S. Vasan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Rare Variants of IFIH1, a Gene Implicated in Antiviral Responses, Protect Against Type 1 Diabetes

(2009) S. Nejentsev et al.   SCIENCE

Methods for Detecting Associations with Rare Variants for Common Diseases: Application to Analysis of Sequence Data

(2008) Bingshan Li et al.   AMERICAN JOURNAL OF HUMAN GENETICS