Gintonin Mitigates MPTP-Induced Loss of Nigrostriatal Dopaminergic Neurons and Accumulation of α-Synuclein via the Nrf2/HO-1 Pathway
出版年份 2018 全文链接
标题
Gintonin Mitigates MPTP-Induced Loss of Nigrostriatal Dopaminergic Neurons and Accumulation of α-Synuclein via the Nrf2/HO-1 Pathway
作者
关键词
Gintonin, Neuroprotection, Nrf2/HO-1 pathway, Parkinson’s disease, MPTP, Neuroinflammation
出版物
MOLECULAR NEUROBIOLOGY
Volume -, Issue -, Pages -
出版商
Springer Nature
发表日期
2018-04-20
DOI
10.1007/s12035-018-1020-1
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Role of Autophagy in Parkinson’s Disease
- (2018) Silvia Cerri et al. CURRENT MEDICINAL CHEMISTRY
- Comparison of clinical features among Parkinson's disease subtypes: A large retrospective study in a single center
- (2018) Takuya Konno et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- α-synuclein (SNCA ) but not dynamin 3 (DNM3 ) influences age at onset of leucine-rich repeat kinase 2 (LRRK2) Parkinson's disease in Spain
- (2018) Rubén Fernández-Santiago et al. MOVEMENT DISORDERS
- Gintonin, a Ginseng-Derived Lysophosphatidic Acid Receptor Ligand, Attenuates Alzheimer's Disease-Related Neuropathies: Involvement of Non-Amyloidogenic Processing
- (2018) Sung Hee Hwang et al. JOURNAL OF ALZHEIMERS DISEASE
- Nrf2 activation by tauroursodeoxycholic acid in experimental models of Parkinson's disease
- (2017) Sara Moreira et al. EXPERIMENTAL NEUROLOGY
- Gintonin attenuates depressive-like behaviors associated with alcohol withdrawal in mice
- (2017) Hyeon-Joong Kim et al. JOURNAL OF AFFECTIVE DISORDERS
- 17β-Estradiol via SIRT1/Acetyl-p53/NF-kB Signaling Pathway Rescued Postnatal Rat Brain Against Acute Ethanol Intoxication
- (2017) Mehtab Khan et al. MOLECULAR NEUROBIOLOGY
- The SH-SY5Y cell line in Parkinson’s disease research: a systematic review
- (2017) Helena Xicoy et al. Molecular Neurodegeneration
- Neuroprotective effects of Kukoamine A on neurotoxin-induced Parkinson's model through apoptosis inhibition and autophagy enhancement
- (2017) XiaoLong Hu et al. NEUROPHARMACOLOGY
- Neuroprotective properties of icariin in MPTP-induced mouse model of Parkinson's disease: Involvement of PI3K/Akt and MEK/ERK signaling pathways
- (2017) Wen-Fang Chen et al. PHYTOMEDICINE
- Neuroprotective Effect and Mechanism of Thiazolidinedione on Dopaminergic Neurons In Vivo and In Vitro in Parkinson’s Disease
- (2017) Yanqin Wang et al. PPAR Research
- Vanillic acid attenuates Aβ1-42-induced oxidative stress and cognitive impairment in mice
- (2017) Faiz Ul Amin et al. Scientific Reports
- Isobavachalcone Attenuates MPTP-Induced Parkinson's Disease in Mice by Inhibition of Microglial Activation through NF-κB Pathway
- (2017) Haoran Jing et al. PLoS One
- Nesfatin-1 protects dopaminergic neurons against MPP+/MPTP-induced neurotoxicity through the C-Raf–ERK1/2-dependent anti-apoptotic pathway
- (2017) Xiao-Li Shen et al. Scientific Reports
- Suppression of adiponectin receptor 1 promotes memory dysfunction and Alzheimer’s disease-like pathologies
- (2017) Min Woo Kim et al. Scientific Reports
- Melatonin Stimulates the SIRT1/Nrf2 Signaling Pathway Counteracting Lipopolysaccharide (LPS)-Induced Oxidative Stress to Rescue Postnatal Rat Brain
- (2016) Shahid Ali Shah et al. CNS Neuroscience & Therapeutics
- S-Glutathionylation of Keap1: a new role for glutathioneS-transferase pi in neuronal protection
- (2016) Andreia Neves Carvalho et al. FEBS LETTERS
- Resveratrol alleviates MPTP-induced motor impairments and pathological changes by autophagic degradation of α-synuclein via SIRT1-deacetylated LC3
- (2016) Yan-Jie Guo et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Gintonin enhances performance of mice in rotarod test: Involvement of lysophosphatidic acid receptors and catecholamine release
- (2016) Byung-Hwan Lee et al. NEUROSCIENCE LETTERS
- Nrf2 mitigates LRRK2- and α-synuclein–induced neurodegeneration by modulating proteostasis
- (2016) Gaia Skibinski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neuroprotective effect of matrine on MPTP-induced Parkinson's disease and on Nrf2 expression
- (2016) Fanhua Meng et al. Oncology Letters
- Osmotin attenuates LPS-induced neuroinflammation and memory impairments via the TLR4/NFκB signaling pathway
- (2016) Haroon Badshah et al. Scientific Reports
- Sulforaphane protects against rotenone-induced neurotoxicity in vivo: Involvement of the mTOR, Nrf2 and autophagy pathways
- (2016) Qian Zhou et al. Scientific Reports
- Hippocampus-dependent cognitive enhancement induced by systemic gintonin administration
- (2016) Sungmin Kim et al. Journal of Ginseng Research
- Neuroprotective Effects of Salidroside in the MPTP Mouse Model of Parkinson’s Disease: Involvement of the PI3K/Akt/GSK3βPathway
- (2016) Wei Zhang et al. Parkinsons Disease
- Alpha-Synuclein in Parkinson’s Disease: From Pathogenetic Dysfunction to Potential Clinical Application
- (2016) Lingjia Xu et al. Parkinsons Disease
- Mitochondrial dysfunction in Parkinson’s disease
- (2016) Qingsong Hu et al. Translational Neurodegeneration
- Assessment of the Effects of MPTP and Paraquat on Dopaminergic Neurons and Microglia in the Substantia Nigra Pars Compacta of C57BL/6 Mice
- (2016) Richard Jay Smeyne et al. PLoS One
- Candidate genes for Parkinson disease: Lessons from pathogenesis
- (2015) Priscilla De Rosa et al. CLINICA CHIMICA ACTA
- Synaptic enhancement induced by gintonin via lysophosphatidic acid receptor activation in central synapses
- (2015) Hoyong Park et al. JOURNAL OF NEUROPHYSIOLOGY
- Oral Administration of Gintonin Attenuates Cholinergic Impairments by Scopolamine, Amyloid-β Protein, and Mouse Model of Alzheimer’s Disease
- (2015) Hyeon-Joong Kim et al. MOLECULES AND CELLS
- Gintonin stimulates gliotransmitter release in cortical primary astrocytes
- (2015) Hyunsook Kim et al. NEUROSCIENCE LETTERS
- Gintonin, a novel ginseng-derived lysophosphatidic acid receptor ligand, stimulates neurotransmitter release
- (2015) Sung-Hee Hwang et al. NEUROSCIENCE LETTERS
- Oxidative stress and Parkinson’s disease
- (2015) Javier Blesa et al. Frontiers in Neuroanatomy
- Tyrosine hydroxylase expression and activity in nigrostriatal dopaminergic neurons of MPTP-treated mice at the presymptomatic and symptomatic stages of parkinsonism
- (2014) Elena A. Kozina et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Oxidative Stress-Induced Signaling Pathways Implicated in the Pathogenesis of Parkinson’s Disease
- (2014) Georgia S. Gaki et al. NEUROMOLECULAR MEDICINE
- Parkinson disease: from pathology to molecular disease mechanisms
- (2013) David T. Dexter et al. FREE RADICAL BIOLOGY AND MEDICINE
- A quantitative study of α-synuclein pathology in fifteen cases of dementia associated with Parkinson disease
- (2013) Richard A. Armstrong et al. JOURNAL OF NEURAL TRANSMISSION
- Parkinson's disease in the nuclear age of neuroinflammation
- (2013) Yvonne M. Nolan et al. TRENDS IN MOLECULAR MEDICINE
- A Guide to Neurotoxic Animal Models of Parkinson's Disease
- (2013) K. Tieu Cold Spring Harbor Perspectives in Medicine
- Clinical Approach to Parkinson's Disease: Features, Diagnosis, and Principles of Management
- (2013) J. Massano et al. Cold Spring Harbor Perspectives in Medicine
- Mitochondria drive autophagy pathology via microtubule disassembly
- (2012) Daniela M. Arduíno et al. Autophagy
- Tauroursodeoxycholic Acid Prevents MPTP-Induced Dopaminergic Cell Death in a Mouse Model of Parkinson’s Disease
- (2012) M. Castro-Caldas et al. MOLECULAR NEUROBIOLOGY
- Gintonin, a ginseng-derived novel ingredient, evokes long-term potentiation through N-methyl-D-aspartic acid receptor activation: Involvement of LPA receptors
- (2012) Tae-Joon Shin et al. MOLECULES AND CELLS
- Effects of Sun Ginseng on Memory Enhancement and Hippocampal Neurogenesis
- (2012) Chang Hwan Lee et al. PHYTOTHERAPY RESEARCH
- Therapeutic Effect of Korean Red Ginseng on Inflammatory Cytokines in Rats with Focal Cerebral Ischemia/Reperfusion Injury
- (2011) Jong Seok Lee et al. AMERICAN JOURNAL OF CHINESE MEDICINE
- Resistance to MPTP-Neurotoxicity in α-Synuclein Knockout Mice Is Complemented by Human α-Synuclein and Associated with Increased β-Synuclein and Akt Activation
- (2011) Bobby Thomas et al. PLoS One
- Novel Glycolipoproteins from Ginseng
- (2011) Mi-Kyung Pyo et al. Journal of Ginseng Research
- Behavioral phenotyping of mouse models of Parkinson's disease
- (2010) Tonya N. Taylor et al. BEHAVIOURAL BRAIN RESEARCH
- PINK1 cleavage at position A103 by the mitochondrial protease PARL
- (2010) Emma Deas et al. HUMAN MOLECULAR GENETICS
- Mitochondrial dysfunction in Parkinson's disease
- (2009) Konstanze F. Winklhofer et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Redox Regulation of Cell Survival
- (2008) Dunyaporn Trachootham et al. ANTIOXIDANTS & REDOX SIGNALING
- Targets for neuroprotection in Parkinson's disease
- (2008) Talene A. Yacoubian et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- An open-label trial of Korean red ginseng as an adjuvant treatment for cognitive impairment in patients with Alzheimers disease
- (2008) J.-H. Heo et al. EUROPEAN JOURNAL OF NEUROLOGY
- Nrf2-induced antioxidant protection: A promising target to counteract ROS-mediated damage in neurodegenerative disease?
- (2008) Helga E. de Vries et al. FREE RADICAL BIOLOGY AND MEDICINE
- Neuroprotective effect of baicalein against MPTP neurotoxicity: Behavioral, biochemical and immunohistochemical profile
- (2008) Yinxia Cheng et al. NEUROSCIENCE LETTERS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now