Alpha-Synuclein in Parkinson’s Disease: From Pathogenetic Dysfunction to Potential Clinical Application
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Alpha-Synuclein in Parkinson’s Disease: From Pathogenetic Dysfunction to Potential Clinical Application
Authors
Keywords
-
Journal
Parkinsons Disease
Volume 2016, Issue -, Pages 1-10
Publisher
Hindawi Limited
Online
2016-08-18
DOI
10.1155/2016/1720621
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Value of cerebrospinal fluid α-synuclein species as biomarker in Parkinson's diagnosis and prognosis
- (2016) Lucilla Parnetti et al. Biomarkers in Medicine
- α-Synuclein in Extracellular Vesicles: Functional Implications and Diagnostic Opportunities
- (2016) Camilla Lööv et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Targeting the Autophagy/Lysosomal Degradation Pathway in Parkinsons Disease
- (2016) Pilar Rivero-Ríos et al. Current Neuropharmacology
- Peripheral Synucleinopathy in Early Parkinson's Disease: Submandibular Gland Needle Biopsy Findings
- (2016) Charles H. Adler et al. MOVEMENT DISORDERS
- Targeting α-synuclein: Therapeutic options
- (2016) Benjamin Dehay et al. MOVEMENT DISORDERS
- Dynamic structural flexibility of α-synuclein
- (2016) Danielle E. Mor et al. NEUROBIOLOGY OF DISEASE
- Skin nerve misfolded α-synuclein in pure autonomic failure and Parkinson disease
- (2015) Vincenzo Donadio et al. ANNALS OF NEUROLOGY
- Phosphorylated α-synuclein in skin nerve fibres differentiates Parkinson’s disease from multiple system atrophy
- (2015) Leonora Zange et al. BRAIN
- Peripheral synuclein tissue markers: a step closer to Parkinson’s disease diagnosis: Figure 1
- (2015) Eduardo Tolosa et al. BRAIN
- Effects of Serine 129 Phosphorylation on α-Synuclein Aggregation, Membrane Association, and Internalization
- (2015) Filsy Samuel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Definition of a Molecular Pathway Mediating -Synuclein Neurotoxicity
- (2015) J. Burre et al. JOURNAL OF NEUROSCIENCE
- Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations
- (2015) Benjamin Dehay et al. LANCET NEUROLOGY
- α-Synuclein strains cause distinct synucleinopathies after local and systemic administration
- (2015) W. Peelaerts et al. NATURE
- Structure of the toxic core of α-synuclein from invisible crystals
- (2015) Jose A. Rodriguez et al. NATURE
- Autophagy in neurodegenerative diseases: From pathogenic dysfunction to therapeutic modulation
- (2015) Marta Martinez-Vicente SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Gastrointestinal Biopsies for the Diagnosis of Alpha-Synuclein Pathology in Parkinson’s Disease
- (2015) Maria Graciela Cersosimo Gastroenterology Research and Practice
- Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters
- (2015) Charles P. Lai et al. Nature Communications
- The Diagnostic and Differential Diagnosis Utility of Cerebrospinal Fluidα-Synuclein Levels in Parkinson’s Disease: A Meta-Analysis
- (2015) Bo Zhou et al. Parkinsons Disease
- Alpha-synuclein Toxicity in the Early Secretory Pathway: How It Drives Neurodegeneration in Parkinsons Disease
- (2015) Ting Wang et al. Frontiers in Neuroscience
- Urinary Extracellular Vesicles as Source of Biomarkers in Kidney Diseases
- (2015) Ana Gámez-Valero et al. Frontiers in Immunology
- Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury
- (2015) Ayse Ulusoy et al. Acta Neuropathologica Communications
- Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials
- (2014) Markus Mandler et al. ACTA NEUROPATHOLOGICA
- The Ubiquitin-Proteasome System in Neurodegeneration
- (2014) Chris McKinnon et al. ANTIOXIDANTS & REDOX SIGNALING
- Defined α-synuclein prion-like molecular assemblies spreading in cell culture
- (2014) Suzana Aulić et al. BMC NEUROSCIENCE
- Cerebrospinal fluid alpha-synuclein as a biomarker for Parkinson's disease diagnosis: a systematic review and meta-analysis
- (2014) Liang Gao et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- Pharmacological Treatment of Parkinson Disease
- (2014) Barbara S. Connolly et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Acceleration of α-Synuclein Aggregation by Exosomes
- (2014) Marie Grey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cutaneous autonomic denervation in Parkinson’s disease
- (2014) Judith Navarro-Otano et al. JOURNAL OF NEURAL TRANSMISSION
- Reducing C-Terminal-Truncated Alpha-Synuclein by Immunotherapy Attenuates Neurodegeneration and Propagation in Parkinson's Disease-Like Models
- (2014) D. Games et al. JOURNAL OF NEUROSCIENCE
- In vivo gastric detection of α-synuclein inclusions in Parkinson's disease
- (2014) Álvaro Sánchez-Ferro et al. MOVEMENT DISORDERS
- A novel α-synuclein mutation A53E associated with atypical multiple system atrophy and Parkinson's disease-type pathology
- (2014) Petra Pasanen et al. NEUROBIOLOGY OF AGING
- Alpha-synuclein spreading in Parkinson’s disease
- (2014) Ariadna Recasens et al. Frontiers in Neuroanatomy
- α-Synuclein Immunotherapy Blocks Uptake and Templated Propagation of Misfolded α-Synuclein and Neurodegeneration
- (2014) Hien T. Tran et al. Cell Reports
- Alpha-Synuclein Function and Dysfunction on Cellular Membranes
- (2014) David Snead et al. Experimental Neurobiology
- G51D α-synuclein mutation causes a novel Parkinsonian-pyramidal syndrome
- (2013) Suzanne Lesage et al. ANNALS OF NEUROLOGY
- Alpha-synuclein Post-translational Modifications as Potential Biomarkers for Parkinson Disease and Other Synucleinopathies
- (2013) Adrien W. Schmid et al. MOLECULAR & CELLULAR PROTEOMICS
- Submandibular gland biopsy for the diagnosis of Parkinson's disease
- (2013) Athanasia Alexoudi et al. MOVEMENT DISORDERS
- Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease
- (2013) Silke Appel-Cresswell et al. MOVEMENT DISORDERS
- Properties of native brain α-synuclein
- (2013) Jacqueline Burré et al. NATURE
- α-Synuclein knockout mice have cognitive impairments
- (2012) V.S. Kokhan et al. BEHAVIOURAL BRAIN RESEARCH
- Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
- (2012) Kelvin C. Luk et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Lewy Body in Parkinson’s Disease and Related Neurodegenerative Disorders
- (2012) Koichi Wakabayashi et al. MOLECULAR NEUROBIOLOGY
- The many faces of α-synuclein: from structure and toxicity to therapeutic target
- (2012) Hilal A. Lashuel et al. NATURE REVIEWS NEUROSCIENCE
- Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo
- (2012) Elodie Angot et al. PLoS One
- The ubiquitin proteasome system in neurodegenerative diseases: Culprit, accomplice or victim?
- (2012) F.J.A. Dennissen et al. PROGRESS IN NEUROBIOLOGY
- Pathological -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
- (2012) K. C. Luk et al. SCIENCE
- A Unifying Role for Prions in Neurodegenerative Diseases
- (2012) S. B. Prusiner SCIENCE
- Salivary α-synuclein and DJ-1: potential biomarkers for Parkinson's disease
- (2011) Ivana Devic et al. BRAIN
- α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
- (2011) Christian Hansen et al. JOURNAL OF CLINICAL INVESTIGATION
- Distinct Roles In Vivo for the Ubiquitin-Proteasome System and the Autophagy-Lysosomal Pathway in the Degradation of -Synuclein
- (2011) D. Ebrahimi-Fakhari et al. JOURNAL OF NEUROSCIENCE
- Alpha-synuclein in colonic submucosa in early untreated Parkinson's disease
- (2011) Kathleen M. Shannon et al. MOVEMENT DISORDERS
- α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation
- (2011) Tim Bartels et al. NATURE
- Priorities in Parkinson's disease research
- (2011) Wassilios G. Meissner et al. NATURE REVIEWS DRUG DISCOVERY
- α-Synuclein Reactive Antibodies as Diagnostic Biomarkers in Blood Sera of Parkinson's Disease Patients
- (2011) Kiran Yanamandra et al. PLoS One
- Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disorders
- (2010) Thomas G. Beach et al. ACTA NEUROPATHOLOGICA
- Co-expression of C-terminal truncated alpha-synuclein enhances full-length alpha-synuclein-induced pathology
- (2010) Ayse Ulusoy et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies
- (2010) He-Jin Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cell-Produced -Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival
- (2010) E. Emmanouilidou et al. JOURNAL OF NEUROSCIENCE
- Alpha-synuclein immunoreactivity in minor salivary gland biopsies of Parkinson's disease patients
- (2010) Maria Graciela Cersósimo et al. MOVEMENT DISORDERS
- Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis
- (2010) Venu M. Nemani et al. NEURON
- Significance and confounders of peripheral DJ-1 and alpha-synuclein in Parkinson's disease
- (2010) Min Shi et al. NEUROSCIENCE LETTERS
- -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
- (2010) J. Burre et al. SCIENCE
- Insulin-like growth factor-I receptor signal transduction and the Janus Kinase/Signal Transducer and Activator of Transcription (JAK-STAT) pathway
- (2009) Eddy Himpe et al. BIOFACTORS
- Pre-fibrillar α-synuclein variants with impaired β-structure increase neurotoxicity in Parkinson's disease models
- (2009) Damla Pinar Karpinar et al. EMBO JOURNAL
- Clinical availability of skin biopsy in the diagnosis of Parkinson's disease
- (2009) Yasuo Miki et al. NEUROSCIENCE LETTERS
- Inclusion formation and neuronal cell death through neuron-to-neuron transmission of -synuclein
- (2009) P. Desplats et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathological lesions in colonic biopsies during Parkinson's disease
- (2008) T Lebouvier et al. GUT
- Polo-like Kinase 2 (PLK2) Phosphorylates α-Synuclein at Serine 129 in Central Nervous System
- (2008) Kelly J. Inglis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started