Programmed Cell Death, from a Cancer Perspective: An Overview

Epithelial cell adhesion molecule overexpression regulates epithelial-mesenchymal transition, stemness and metastasis of nasopharyngeal carcinoma cells via the PTEN/AKT/mTOR pathway

(2018) Meng-He Wang et al.   Cell Death & Disease

Deptor: not only a mTOR inhibitor

(2017) Valeria Catena et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Therapeutic strategies of drug repositioning targeting autophagy to induce cancer cell death: from pathophysiology to treatment

(2017) Go J. Yoshida   Journal of Hematology & Oncology

Biological Activities of Essential Oils: From Plant Chemoecology to Traditional Healing Systems

(2017) Javad Sharifi-Rad et al.   MOLECULES

Downregulation of DEPTOR inhibits the proliferation, migration, and survival of osteosarcoma through PI3K/Akt/mTOR pathway

(2017) Binwu Hu et al.   OncoTargets and Therapy

JNK pathway mediates curcumin-induced apoptosis and autophagy in osteosarcoma MG63 cells

(2017) Yaowu Zhang et al.   Experimental and Therapeutic Medicine

Exploitation of necroptosis for treatment of caspase-compromised cancers

(2017) Young Sik Cho et al.   Oncology Letters

Downregulation of ATG5-dependent macroautophagy by chaperone-mediated autophagy promotes breast cancer cell metastasis

(2017) Qi Han et al.   Scientific Reports

Necroptosis and Inflammation

(2016) Kim Newton et al.   Annual Review of Biochemistry

Ferroptosis is an autophagic cell death process

(2016) Minghui Gao et al.   CELL RESEARCH

New derivatives of the antimalarial drug Pyrimethamine in the control of melanoma tumor growth: an in vitro and in vivo study

(2016) Chiara Tommasino et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

In Situ Characterization of Bak Clusters Responsible for Cell Death Using Single Molecule Localization Microscopy

(2016) Yusuke Nasu et al.   Scientific Reports

Drug repositioning and repurposing: terminology and definitions in literature

(2015) Joris Langedijk et al.   DRUG DISCOVERY TODAY

Apoptosis, autophagy, necroptosis, and cancer metastasis

(2015) Zhenyi Su et al.   Molecular Cancer

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

Emerging strategies to effectively target autophagy in cancer

(2015) V W Rebecca et al.   ONCOGENE

Harnessing of Programmed Necrosis for Fighting against Cancers

(2014) Young Sik Cho et al.   Biomolecules & Therapeutics

To Be or Not to Be? How Selective Autophagy and Cell Death Govern Cell Fate

(2014) Douglas R. Green et al.   CELL

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Autophagic Cell Death and Cancer

(2014) Shigeomi Shimizu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Self-consumption: the interplay of autophagy and apoptosis

(2014) Guillermo Mariño et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Necroptotic signaling in adaptive and innate immunity

(2014) Jennifer V. Lu et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Targeting Apoptosis Pathways for New Cancer Therapeutics

(2013) Longchuan Bai et al.   Annual Review of Medicine

The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis

(2013) Zeze Fu et al.   BMC CANCER

Chaperone-mediated autophagy: roles in disease and aging

(2013) Ana Maria Cuervo et al.   CELL RESEARCH

Chaperone-mediated autophagy degrades mutant p53

(2013) H. Vakifahmetoglu-Norberg et al.   GENES & DEVELOPMENT

Epithelial cell adhesion molecule (EpCAM) is associated with prostate cancer metastasis and chemo/radioresistance via the PI3K/Akt/mTOR signaling pathway

(2013) Jie Ni et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Autophagy, Apoptosis, Mitoptosis and Necrosis: Interdependence Between Those Pathways and Effects on Cancer

(2012) Wiem Chaabane et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

(2012) Liming Sun et al.   CELL

Molecules and their functions in autophagy

(2012) Jong-Ok Pyo et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

The regulation of cancer cell death and metabolism by extracellular matrix attachment

(2012) Cassandra L. Buchheit et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Targeting autophagic pathways for cancer drug discovery

(2012) Bo Liu et al.   Chinese Journal of Cancer

Resveratrol as an adjunct therapy in cyclophosphamide-treated MCF-7 cells and breast tumor explants

(2011) Neetu Singh et al.   CANCER SCIENCE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Core signaling pathways of survival/death in autophagy-related cancer networks

(2011) Shu-ya Wang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Apoptosis in cancer: from pathogenesis to treatment

(2011) Rebecca SY Wong   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Mechanisms of necroptosis in T cells

(2011) Irene L. Ch’en et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs

(2011) Tencho Tenev et al.   MOLECULAR CELL

Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway

(2011) S. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity

(2011) J. V. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macroautophagy and ERK phosphorylation counteract the anti-proliferative effect of proteasome inhibitor in gastric cancer cells

(2010) William Ka Kei Wu et al.   Autophagy

Caspase-8 as a therapeutic target in cancer

(2010) Dwayne G. Stupack   CANCER LETTERS

Necroptosis as an alternative form of programmed cell death

(2010) Dana E Christofferson et al.   CURRENT OPINION IN CELL BIOLOGY

GSK-3β promotes cell survival by modulating Bif-1-dependent autophagy and cell death

(2010) Jun Yang et al.   JOURNAL OF CELL SCIENCE

Centchroman mediated apoptosis involves cross-talk between extrinsic/intrinsic pathways and oxidative regulation

(2010) Manisha Nigam et al.   LIFE SCIENCES

The BCL-2 Family Reunion

(2010) Jerry E. Chipuk et al.   MOLECULAR CELL

Molecular mechanisms of necroptosis: an ordered cellular explosion

(2010) Peter Vandenabeele et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Involvement of JNK in the regulation of autophagic cell death

(2010) S Shimizu et al.   ONCOGENE

Astrocyte elevated gene-1 induces protective autophagy

(2010) S. K. Bhutia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of the Kinases RIP1 and RIP3 in TNF-Induced Necrosis

(2010) P. Vandenabeele et al.   Science Signaling

p53 and ARF: unexpected players in autophagy

(2010) Gregor M. Balaburski et al.   TRENDS IN CELL BIOLOGY

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

(2009) YoungSik Cho et al.   CELL

Apoptosis and autophagy: Targeting autophagy signalling in cancer cells -‘trick or treats’?

(2009) Elisabeth A. Corcelle et al.   FEBS Journal

Caspase Mediated Enhanced Apoptotic Action of Cyclophosphamide- and Resveratrol-Treated MCF-7 Cells

(2009) Neetu Singh et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Programmed Cell Death Pathways and Current Antitumor Targets

(2009) Mei Lan Tan et al.   PHARMACEUTICAL RESEARCH

p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling

(2008) Andrei V. Budanov et al.   CELL

Targeting the extrinsic apoptosis pathway in cancer

(2008) Avi Ashkenazi   CYTOKINE & GROWTH FACTOR REVIEWS

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

(2008) Taichi Hara et al.   JOURNAL OF CELL BIOLOGY

Centchroman induces G0/G1 arrest and Caspase-dependent Apoptosis involving Mitochondrial Membrane Depolarization in MCF-7 and MDA MB-231 Human Breast Cancer Cells

(2008) Manisha Nigam et al.   LIFE SCIENCES