Harnessing of Programmed Necrosis for Fighting against Cancers

Autophagy activity contributes to programmed cell death inCaenorhabditis elegans

(2013) Haibin Wang et al.   Autophagy

Defective immunogenic cell death of HMGB1-deficient tumors: compensatory therapy with TLR4 agonists

(2013) T Yamazaki et al.   CELL DEATH AND DIFFERENTIATION

RIP3: a molecular switch for necrosis and inflammation

(2013) K. Moriwaki et al.   GENES & DEVELOPMENT

Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance

(2013) Agnieszka Kaczmarek et al.   IMMUNITY

Negatively-regulated necroptosis by autophagy required caspase-6 activation in TNFα-treated murine fibrosarcoma L929 cells

(2013) Yuan-Chao Ye et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development

(2013) Mayur V. Jain et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Rottlerin-induced autophagy leads to the apoptosis in breast cancer stem cells: molecular mechanisms

(2013) Dhruv Kumar et al.   Molecular Cancer

Shikonin Kills Glioma Cells through Necroptosis Mediated by RIP-1

(2013) Chuanjiang Huang et al.   PLoS One

CYLD Deubiquitinates RIP1 in the TNFα-Induced Necrosome to Facilitate Kinase Activation and Programmed Necrosis

(2013) David M. Moquin et al.   PLoS One

TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1

(2013) D M Moujalled et al.   Cell Death & Disease

A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells

(2013) A D Kim et al.   Cell Death & Disease

An NQO1 Substrate with Potent Antitumor Activity That Selectively Kills by PARP1-Induced Programmed Necrosis

(2012) X. Huang et al.   CANCER RESEARCH

A role for c-FLIPL in the regulation of apoptosis, autophagy and necroptosis in T lymphocytes

(2012) M-X He et al.   CELL DEATH AND DIFFERENTIATION

Anti-tumor immunity, autophagy and chemotherapy

(2012) Györgyi Műzes   WORLD JOURNAL OF GASTROENTEROLOGY

A novel role for RIP1 kinase in mediating TNFα production

(2012) D E Christofferson et al.   Cell Death & Disease

The crosstalk between autophagy and apoptosis: where does this lead?

(2012) Claire Gordy et al.   Protein & Cell

Programmed cell death and its possible relationship with periodontal disease

(2012) Hiromasa Tsuda et al.   Journal of Oral Science

zVAD-induced autophagic cell death requires c-Src-dependent ERK and JNK activation and reactive oxygen species generation

(2011) Szu-Ying Chen et al.   Autophagy

The Beclin 1 network regulates autophagy and apoptosis

(2011) R Kang et al.   CELL DEATH AND DIFFERENTIATION

Inhibition of active autophagy induces apoptosis and increases chemosensitivity in cholangiocarcinoma

(2011) Yu-Jie Hou et al.   LABORATORY INVESTIGATION

The Role of Autophagy in Cancer: Therapeutic Implications

(2011) Z. J. Yang et al.   MOLECULAR CANCER THERAPEUTICS

cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms

(2011) Maria Feoktistova et al.   MOLECULAR CELL

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Cell death assays for drug discovery

(2011) Oliver Kepp et al.   NATURE REVIEWS DRUG DISCOVERY

Ripoptosome: a novel IAP-regulated cell death-signalling platform

(2011) G. Imre et al.   Journal of Molecular Cell Biology

Disruption of the MDM2–p53 interaction strongly potentiates p53-dependent apoptosis in cisplatin-resistant human testicular carcinoma cells via the Fas/FasL pathway

(2011) R Koster et al.   Cell Death & Disease

Targeting the Anti-Apoptotic Protein c-FLIP for Cancer Therapy

(2011) Ahmad R. Safa et al.   Cancers

Defective autophagy associated with LC3 puncta in epothilone-resistant cancer cells

(2010) Shensi Shen et al.   CELL CYCLE

zVAD-induced necroptosis in L929 cells depends on autocrine production of TNFα mediated by the PKC–MAPKs–AP-1 pathway

(2010) Y-T Wu et al.   CELL DEATH AND DIFFERENTIATION

Necroptosis as an alternative form of programmed cell death

(2010) Dana E Christofferson et al.   CURRENT OPINION IN CELL BIOLOGY

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Autophagosome formation in mammalian cells

(2010) Chloe Burman et al.   Seminars in Immunopathology

Cell Death Mechanisms and Their Implications in Toxicology

(2010) Sten Orrenius et al.   TOXICOLOGICAL SCIENCES

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

(2009) YoungSik Cho et al.   CELL

Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells: potential for therapy of myeloid leukemia and myelodysplastic syndromes

(2009) T. J. Gaymes et al.   HAEMATOLOGICA

RIP Kinases Initiate Programmed Necrosis

(2009) L. Galluzzi et al.   Journal of Molecular Cell Biology

CD133-positive cells are resistant to TRAIL due to up-regulation of FLIP

(2008) Renata Zobalova et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Caspase-mediated cleavage of ATG6/Beclin-1 links apoptosis to autophagy in HeLa cells

(2008) Dong-Hyung Cho et al.   CANCER LETTERS