New Insights into Behçet’s Syndrome Metabolic Reprogramming: Citrate Pathway Dysregulation

Metabolic routes in inflammation: the citrate pathway and its potential as therapeutic target

(2018) Vittoria Infantino et al.   CURRENT MEDICINAL CHEMISTRY

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

(2018) Evanna L. Mills et al.   NATURE

Krebs cycle rewired for macrophage and dendritic cell effector functions

(2017) Dylan Gerard Ryan et al.   FEBS LETTERS

An elevated pro-inflammatory cytokines profile in Behcet’s disease: A multiplex analysis

(2017) Nasser Gholijani et al.   IMMUNOLOGY LETTERS

Genetics and immunodysfunction underlying Behçet’s disease and immunomodulant treatment approaches

(2017) Arash Salmaninejad et al.   Journal of Immunotoxicology

Fine tuning of immunometabolism for the treatment of rheumatic diseases

(2017) Jillian P. Rhoads et al.   Nature Reviews Rheumatology

The Role of Th17 Cells in the Pathogenesis of Behcet’s Disease

(2017) Yuki Nanke et al.   Journal of Clinical Medicine

A single endoplasmic reticulum aminopeptidase-1 protein allotype is a strong risk factor for Behçet's disease in HLA-B*51 carriers

(2016) Masaki Takeuchi et al.   ANNALS OF THE RHEUMATIC DISEASES

Immunometabolic biomarkers of inflammation in Behçet's disease: relationship with epidemiological profile, disease activity and therapeutic regimens

(2016) L. Cantarini et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The contribution of the citrate pathway to oxidative stress in Down syndrome

(2016) Paolo Convertini et al.   IMMUNOLOGY

A Broken Krebs Cycle in Macrophages

(2015) Luke A.J. O’Neill   IMMUNITY

Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization

(2015) Abhishek K. Jha et al.   IMMUNITY

The immunogenetics of Behçet's disease: A comprehensive review

(2015) Masaki Takeuchi et al.   JOURNAL OF AUTOIMMUNITY

Pathogenesis of Behçet’s disease: autoinflammatory features and beyond

(2015) Ahmet Gül   Seminars in Immunopathology

Characterization of the major histocompatibility complex locus association with Behçet’s disease in Iran

(2015) Joana M Xavier et al.   ARTHRITIS RESEARCH & THERAPY

Brief Report: Association ofCCR1,KLRC4,IL12A-AS1,STAT4, andERAP1With Behçet's Disease in Iranians

(2015) Inês Sousa et al.   Arthritis & Rheumatology

A key role of the mitochondrial citrate carrier (SLC25A1) in TNFα- and IFNγ-triggered inflammation

(2014) Vittoria Infantino et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Citrate – new functions for an old metabolite

(2014) Vito Iacobazzi et al.   BIOLOGICAL CHEMISTRY

Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes

(2014) Nathalie Esser et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

ATP-citrate lyase is essential for macrophage inflammatory response

(2013) Vittoria Infantino et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production

(2013) A. Michelucci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Behçet's Syndrome

(2013) Gulen Hatemi et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

The mitochondrial citrate carrier: a new player in inflammation

(2011) Vittoria Infantino et al.   BIOCHEMICAL JOURNAL