The Role of Th17 Cells in the Pathogenesis of Behcet’s Disease

Cytotoxic Th1 and Th17 cells infiltrate the intestinal mucosa of Behcet patients and exhibit high levels of TNF-α in early phases of the disease

(2016) Giacomo Emmi et al.   MEDICINE

IFN-α induces IL-10 production and tilt the balance between Th1 and Th17 in Behçet disease

(2015) Maxime Touzot et al.   AUTOIMMUNITY REVIEWS

Genetic Variations of IL17F and IL23A Show Associations with Behçet’s Disease and Vogt-Koyanagi-Harada Syndrome

(2015) Shengping Hou et al.   OPHTHALMOLOGY

IL-22-secreting Th22 and IFN-γ-secreting Th17 cells in Behçet's disease

(2014) Esin Aktas Cetin et al.   Modern Rheumatology

Decreased interleukin 27 expression is associated with active uveitis in Behçet’s disease

(2014) Chaokui Wang et al.   ARTHRITIS RESEARCH & THERAPY

Expression of Th-17 and RORgammat mRNA in Behçet’s Disease

(2013) Kamel Hamzaoui et al.   MEDICAL SCIENCE MONITOR

Identification of a susceptibility locus inSTAT4for Behçet's disease in Han Chinese in a genome-wide association study

(2012) Shengping Hou et al.   ARTHRITIS AND RHEUMATISM

Interactions between IL17A, IL23R, and STAT4 polymorphisms confer susceptibility to intestinal Behcet's disease in Korean population

(2012) Eun Soo Kim et al.   LIFE SCIENCES

Inhibition of Th17 differentiation by anti-TNF-alpha therapy in uveitis patients with Behçet's disease

(2012) Sunao Sugita et al.   ARTHRITIS RESEARCH & THERAPY

Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritis

(2011) Lorenzo Cosmi et al.   ARTHRITIS AND RHEUMATISM

Excessive CD4+ T cells co-expressing interleukin-17 and interferon-γ in patients with Behçet's disease

(2011) J. Shimizu et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Regulation of TH17 and regulatory T cells in patients with Behçet disease

(2011) Haner Direskeneli et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Critical role of IL-21 in modulating TH17 and regulatory T cells in Behçet disease

(2011) Guillaume Geri et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

RORC and Foxp3 axis in cerebrospinal fluid of patients with Neuro-Behçet's Disease

(2011) Kamel Hamzaoui et al.   JOURNAL OF NEUROIMMUNOLOGY

IL-23R gene confers susceptibility to Behcet's disease in a Chinese Han population

(2010) Z. Jiang et al.   ANNALS OF THE RHEUMATIC DISEASES

Long-term remission after cessation of interferon-α treatment in patients with severe uveitis due to Behçet's disease

(2010) Christoph M. E. Deuter et al.   ARTHRITIS AND RHEUMATISM

Invariant NKT cells regulate experimental autoimmune uveitis through inhibition of Th17 differentiation

(2010) Keunhee Oh et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-17A Has an Important Role in the Acute Attacks of Behçet's Disease

(2010) Nurten Sayin Ekinci et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci

(2010) Nobuhisa Mizuki et al.   NATURE GENETICS

Genome-wide association study identifies variants in the MHC class I, IL10 and IL23R-IL12RB2 regions associated with Behçet's disease

(2010) Elaine F Remmers et al.   NATURE GENETICS

Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

(2010) K. Nistala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IFN-  blocks IL-17 production by peripheral blood mononuclear cells in Behcet's disease

(2010) X. Liu et al.   RHEUMATOLOGY

Suppression of Experimental Autoimmune Uveoretinitis by Anti-IL-17 Antibody

(2009) Rui Zhang et al.   CURRENT EYE RESEARCH

Transforming growth factor β is dispensable for the molecular orchestration of Th17 cell differentiation

(2009) Jyoti Das et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Major Role of    T Cells in the Generation of IL-17+ Uveitogenic T Cells

(2009) Y. Cui et al.   JOURNAL OF IMMUNOLOGY

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo

(2009) Mandy J McGeachy et al.   NATURE IMMUNOLOGY

Involvement of Th17 cells and the effect of anti-IL-6 therapy in autoimmune uveitis

(2009) T. Yoshimura et al.   RHEUMATOLOGY

Increased expression of interleukin-23 p19 mRNA in erythema nodosum-like lesions of Behçet’s disease

(2008) W. Lew et al.   BRITISH JOURNAL OF DERMATOLOGY

Interleukin-6 small interfering RNA improved the herpes simplex virus-induced systemic inflammation in vivo Behcet’s disease-like mouse model

(2008) J Shim et al.   GENE THERAPY

Tumor necrosis factor alpha small interfering RNA decreases herpes simplex virus-induced inflammation in a mouse model

(2008) Bunsoon Choi et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function

(2008) Liang Zhou et al.   NATURE

Interleukin-17F gene polymorphisms in Korean patients with Behçet’s disease

(2008) Won-Cheoul Jang et al.   RHEUMATOLOGY INTERNATIONAL