The EGFR-ADAM17 Axis in Chronic Obstructive Pulmonary Disease and Cystic Fibrosis Lung Pathology
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Title
The EGFR-ADAM17 Axis in Chronic Obstructive Pulmonary Disease and Cystic Fibrosis Lung Pathology
Authors
Keywords
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Journal
MEDIATORS OF INFLAMMATION
Volume 2018, Issue -, Pages 1-22
Publisher
Hindawi Limited
Online
2018-01-10
DOI
10.1155/2018/1067134
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Note: Only part of the references are listed.- Generation of a gene-corrected isogenic control iPSC line from cystic fibrosis patient-specific iPSCs homozygous for p.Phe508del mutation mediated by TALENs and ssODN
- (2017) Sylvia Merkert et al. Stem Cell Research
- Exosome-delivered EGFR regulates liver microenvironment to promote gastric cancer liver metastasis
- (2017) Haiyang Zhang et al. Nature Communications
- Correction of lung inflammation in a F508del CFTR murine cystic fibrosis model by the sphingosine-1-phosphate lyase inhibitor LX2931
- (2016) Mieke Veltman et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Morphometric Analysis of Explant Lungs in Cystic Fibrosis
- (2016) Mieke Boon et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Stimulated release and functional activity of surface expressed metalloproteinase ADAM17 in exosomes
- (2016) Esther Groth et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- IL6 Trans-signaling Promotes KRAS-Driven Lung Carcinogenesis
- (2016) G. D. Brooks et al. CANCER RESEARCH
- Chronic inflammatory airway diseases: the central role of the epithelium revisited
- (2016) S. T. Gohy et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Acquired Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction in Chronic Bronchitis and Other Diseases of Mucus Clearance
- (2016) S. Vamsee Raju et al. CLINICS IN CHEST MEDICINE
- Genetic Variants inIL6RandADAM19are Associated with COPD Severity in a Mexican Mestizo Population
- (2016) Gloria Pérez-Rubio et al. COPD-Journal of Chronic Obstructive Pulmonary Disease
- STAT3 signaling in immunity
- (2016) Emily J. Hillmer et al. CYTOKINE & GROWTH FACTOR REVIEWS
- The IL6R gene polymorphisms are associated with sIL-6R, IgE and lung function in Chinese patients with asthma
- (2016) Yajun Wang et al. GENE
- Airway epithelial dual oxidase 1 mediates allergen-induced IL-33 secretion and activation of type 2 immune responses
- (2016) Milena Hristova et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Acidic pH increases airway surface liquid viscosity in cystic fibrosis
- (2016) Xiao Xiao Tang et al. JOURNAL OF CLINICAL INVESTIGATION
- Cystic Fibrosis Lung Immunity: The Role of the Macrophage
- (2016) Emanuela M. Bruscia et al. Journal of Innate Immunity
- Cystic fibrosis
- (2016) J Stuart Elborn LANCET
- Enhanced ADAM17 expression is associated with cardiac remodeling in rats with acute myocardial infarction
- (2016) Dong-You Zheng et al. LIFE SCIENCES
- Epithelial Anion Transport as Modulator of Chemokine Signaling
- (2016) Andrea Schnúr et al. MEDIATORS OF INFLAMMATION
- The STAT3 pathway as a therapeutic target in head and neck cancer: Barriers and innovations
- (2016) Jessica L. Geiger et al. ORAL ONCOLOGY
- Airway acidification initiates host defense abnormalities in cystic fibrosis mice
- (2016) V. S. Shah et al. SCIENCE
- Key mechanisms governing resolution of lung inflammation
- (2016) C. T. Robb et al. Seminars in Immunopathology
- EGF-Amphiregulin Interplay in Airway Stem/Progenitor Cells Links the Pathogenesis of Smoking-Induced Lesions in the Human Airway Epithelium
- (2016) Wu-Lin Zuo et al. STEM CELLS
- Lessons learned from the cystic fibrosis pig
- (2016) David K. Meyerholz THERIOGENOLOGY
- Targeted anti-inflammatory therapeutics in asthma and chronic obstructive lung disease
- (2016) Andrew L. Durham et al. Translational Research
- Stress-Induced EGFR Trafficking: Mechanisms, Functions, and Therapeutic Implications
- (2016) Xiaojun Tan et al. TRENDS IN CELL BIOLOGY
- COPD phenotypes on computed tomography and its correlation with selected lung function variables in severe patients
- (2016) Silvia Silva et al. International Journal of Chronic Obstructive Pulmonary Disease
- Bronchiectasis as a Comorbidity of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis
- (2016) Qingxia Du et al. PLoS One
- ADAM-family metalloproteinases in lung inflammation: potential therapeutic targets
- (2015) Daniela Dreymueller et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Human airway smooth muscle cells secrete amphiregulin via bradykinin/COX-2/PGE2, inducing COX-2, CXCL8, and VEGF expression in airway epithelial cells
- (2015) Karl Deacon et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- PRAGMA-CF. A Quantitative Structural Lung Disease Computed Tomography Outcome in Young Children with Cystic Fibrosis
- (2015) Tim Rosenow et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Amphiregulin may be a new biomarker of classically activated macrophages
- (2015) Chen Meng et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Extracellular Juxtamembrane Segment of ADAM17 Interacts with Membranes and Is Essential for Its Shedding Activity
- (2015) Stefan Düsterhöft et al. BIOCHEMISTRY
- Genotypic and phenotypic analyses of a Pseudomonas aeruginosa chronic bronchiectasis isolate reveal differences from cystic fibrosis and laboratory strains
- (2015) John J. Varga et al. BMC GENOMICS
- Airway hydration and COPD
- (2015) Arunava Ghosh et al. CELLULAR AND MOLECULAR LIFE SCIENCES
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- (2015) Tobias Pasqualon et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- JAK–STAT pathway activation in COPD
- (2015) Liang Yew-Booth et al. EUROPEAN RESPIRATORY JOURNAL
- The innate immune function of airway epithelial cells in inflammatory lung disease
- (2015) Pieter S. Hiemstra et al. EUROPEAN RESPIRATORY JOURNAL
- Emerging Functions of Amphiregulin in Orchestrating Immunity, Inflammation, and Tissue Repair
- (2015) Dietmar M.W. Zaiss et al. IMMUNITY
- Shedding of Endogenous Interleukin-6 Receptor (IL-6R) Is Governed by A Disintegrin and Metalloproteinase (ADAM) Proteases while a Full-length IL-6R Isoform Localizes to Circulating Microvesicles
- (2015) Neele Schumacher et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Novel Insights into Interleukin 6 (IL-6) Cis- and Trans-signaling Pathways by Differentially Manipulating the Assembly of the IL-6 Signaling Complex
- (2015) Marine Lacroix et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2015) Gimano D. Amatngalim et al. JOURNAL OF IMMUNOLOGY
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- (2015) Henriette Ebsen et al. MOLECULAR IMMUNOLOGY
- Lumacaftor–Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR
- (2015) Claire E. Wainwright et al. NEW ENGLAND JOURNAL OF MEDICINE
- Epigenetic targets for novel therapies of lung diseases
- (2015) Brian S. Comer et al. PHARMACOLOGY & THERAPEUTICS
- The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17
- (2015) Sarah Louise Dombernowsky et al. Nature Communications
- Second-Hand Cigarette Smoke Impairs Bacterial Phagocytosis in Macrophages by Modulating CFTR Dependent Lipid-Rafts
- (2015) Inzer Ni et al. PLoS One
- Mucociliary clearance and submucosal gland secretion in the ex vivo ferret trachea
- (2014) Jin Hyeok Jeong et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Clinical Mechanism of the Cystic Fibrosis Transmembrane Conductance Regulator Potentiator Ivacaftor in G551D-mediated Cystic Fibrosis
- (2014) Steven M. Rowe et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
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- (2014) Shino Shimizu et al. American Journal of Rhinology & Allergy
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- (2014) Andreas Schmid et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Polymorphisms in the glutathione pathway modulate cystic fibrosis severity: a cross-sectional study
- (2014) Fernando Augusto de Fernando August Marson et al. BMC Medical Genetics
- Targeting EGFR signalling in chronic lung disease: therapeutic challenges and opportunities
- (2014) S. Vallath et al. EUROPEAN RESPIRATORY JOURNAL
- CFTR: cystic fibrosis and beyond
- (2014) M. A. Mall et al. EUROPEAN RESPIRATORY JOURNAL
- Epigenetic mechanisms in COPD: implications for pathogenesis and drug discovery
- (2014) Andrea C Schamberger et al. Expert Opinion on Drug Discovery
- Redox balance in Cystic Fibrosis
- (2014) Assem G. Ziady et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Cystic fibrosis, a multi-systemic mucosal disease: 25 years after the discovery of CFTR
- (2014) Aleksander Edelman et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- A Disintegrin and Metalloprotease 17 Dynamic Interaction Sequence, the Sweet Tooth for the Human Interleukin 6 Receptor
- (2014) Stefan Düsterhöft et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2014) S. Jones et al. JOURNAL OF CELL SCIENCE
- Therapeutic Targeting of IL-6 Trans Signaling Counteracts STAT3 Control of Experimental Inflammatory Arthritis
- (2014) M. A. Nowell et al. JOURNAL OF IMMUNOLOGY
- Blockade of IL-6TransSignaling Attenuates Pulmonary Fibrosis
- (2014) Thanh-Thuy T. Le et al. JOURNAL OF IMMUNOLOGY
- Cystic fibrosis airway epithelium remodelling: involvement of inflammation
- (2014) Damien Adam et al. JOURNAL OF PATHOLOGY
- The findings of a clinical surveillance bronchoalveolar lavage programme in pre-school patients with cystic fibrosis
- (2014) Barry Linnane et al. PEDIATRIC PULMONOLOGY
- IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells
- (2014) T. Tadokoro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- pH modulates the activity and synergism of the airway surface liquid antimicrobials β-defensin-3 and LL-37
- (2014) Mahmoud H. Abou Alaiwa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tracking Lung Clearance Index and chest CT in mild cystic fibrosis lung disease over a period of three years
- (2014) Susanne I. Fuchs et al. RESPIRATORY MEDICINE
- Autocrine ligands of the epithelial growth factor receptor mediate inflammatory responses to diesel exhaust particles
- (2014) Sam Parnia et al. RESPIRATORY RESEARCH
- Interpretation of lung function in infants and young children with cystic fibrosis
- (2014) Kathryn A. Ramsey et al. RESPIROLOGY
- Potentiator ivacaftor abrogates pharmacological correction of F508 CFTR in cystic fibrosis
- (2014) D. M. Cholon et al. Science Translational Medicine
- Central airways remodeling in COPD patients
- (2014) Laura Pini et al. International Journal of Chronic Obstructive Pulmonary Disease
- A CFTR corrector (lumacaftor) and a CFTR potentiator (ivacaftor) for treatment of patients with cystic fibrosis who have a phe508del CFTR mutation: a phase 2 randomised controlled trial
- (2014) Michael P Boyle et al. Lancet Respiratory Medicine
- Human neutrophil elastase-mediated goblet cell metaplasia is attenuated in TACE-deficient mice
- (2013) Jin-Ah Park et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- TACE in perinatal mouse lung epithelial cells promotes lung saccular formation
- (2013) Wei Xu et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Cigarette smoke and CFTR: implications in the pathogenesis of COPD
- (2013) Andras Rab et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Cystic Fibrosis Transmembrane Conductance Regulator Activation by Roflumilast Contributes to Therapeutic Benefit in Chronic Bronchitis
- (2013) James A. Lambert et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Native Small Airways Secrete Bicarbonate
- (2013) A. K. M. Shamsuddin et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Trafficking of Epidermal Growth Factor Receptor Ligands in Polarized Epithelial Cells
- (2013) Bhuminder Singh et al. Annual Review of Physiology
- Assessment of Early Bronchiectasis in Young Children With Cystic Fibrosis Is Dependent on Lung Volume
- (2013) Lauren S. Mott et al. CHEST
- Alternative splicing and proteolytic rupture contribute to the generation of soluble IL-6 receptors (sIL-6R) in rheumatoid arthritis
- (2013) José Ramón Lamas et al. CYTOKINE
- The CFTR and EGFR relationship in airway vascular growth, and its importance in cystic fibrosis
- (2013) Jay A. Nadel EUROPEAN RESPIRATORY JOURNAL
- Early intervention studies in infants and preschool children with cystic fibrosis: are we ready?
- (2013) Stephen Stick et al. EUROPEAN RESPIRATORY JOURNAL
- CFTR dysfunction induces vascular endothelial growth factor synthesis in airway epithelium
- (2013) Clémence Martin et al. EUROPEAN RESPIRATORY JOURNAL
- Minimal Interleukin 6 (IL-6) Receptor Stalk Composition for IL-6 Receptor Shedding and IL-6 Classic Signaling
- (2013) Paul Baran et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Differential Regulation of Inflammation by Inflammatory Mediators in Cystic Fibrosis Lung Epithelial Cells
- (2013) Motohiro Tsuchiya et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Membrane-Proximal Domain of a Disintegrin and Metalloprotease-17 Represents the Putative Molecular Switch of Its Shedding Activity Operated by Protein-disulfide Isomerase
- (2013) Stefan Düsterhöft et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- ADAM17 mediates hypoxia-induced drug resistance in hepatocellular carcinoma cells through activation of EGFR/PI3K/Akt pathway
- (2013) Xiang-jun Wang et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Bronchial epithelium as a target for innovative treatments in asthma
- (2013) Delphine Gras et al. PHARMACOLOGY & THERAPEUTICS
- The Protein Kinase TPL2 Is Essential for ERK1/ERK2 Activation and Cytokine Gene Expression in Airway Epithelial Cells Exposed to Pathogen-Associated Molecular Patterns (PAMPs)
- (2013) Guy Martel et al. PLoS One
- ATP-Mediated Transactivation of the Epidermal Growth Factor Receptor in Airway Epithelial Cells Involves DUOX1-Dependent Oxidation of Src and ADAM17
- (2013) Derek Sham et al. PLoS One
- Dysregulated Proinflammatory and Fibrogenic Phenotype of Fibroblasts in Cystic Fibrosis
- (2013) François Huaux et al. PLoS One
- Normal CFTR Inhibits Epidermal Growth Factor Receptor-Dependent Pro-Inflammatory Chemokine Production in Human Airway Epithelial Cells
- (2013) Suil Kim et al. PLoS One
- Cigarette smoke enhances human rhinovirus-induced CXCL8 production via HuR-mediated mRNA stabilization in human airway epithelial cells
- (2013) Magdalena H Hudy et al. RESPIRATORY RESEARCH
- EGF receptor trafficking: consequences for signaling and cancer
- (2013) Alejandra Tomas et al. TRENDS IN CELL BIOLOGY
- Occupational Exposure to Dusts, Gases, and Fumes and Incidence of Chronic Obstructive Pulmonary Disease in the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults
- (2012) Amar J. Mehta et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Fine PM induce airway MUC5AC expression through the autocrine effect of amphiregulin
- (2012) Stéphanie Val et al. ARCHIVES OF TOXICOLOGY
- Histamine may induce airway remodeling through release of epidermal growth factor receptor ligands from bronchial epithelial cells
- (2012) Nobuaki Hirota et al. FASEB JOURNAL
- The membrane-proximal domain of A Disintegrin and Metalloprotease 17 (ADAM17) is responsible for recognition of the interleukin-6 receptor and interleukin-1 receptor II
- (2012) Inken Lorenzen et al. FEBS LETTERS
- CFTR is the primary known apical glutathione transporter involved in cigarette smoke-induced adaptive responses in the lung
- (2012) Neal S. Gould et al. FREE RADICAL BIOLOGY AND MEDICINE
- IL-6 Trans-Signaling via the Soluble IL-6 Receptor: Importance for the Pro-Inflammatory Activities of IL-6
- (2012) Stefan Rose-John International Journal of Biological Sciences
- Amphiregulin, an Epidermal Growth Factor Receptor Ligand, Plays an Essential Role in the Pathogenesis of Transforming Growth Factor-β-induced Pulmonary Fibrosis
- (2012) Yang Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Disintegrin and Metalloproteinase 17 (ADAM17) and Epidermal Growth Factor Receptor (EGFR) Signaling Drive the Epithelial Response toStaphylococcus aureusToxic Shock Syndrome Toxin-1 (TSST-1)
- (2012) Laura M. Breshears et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A network meta-analysis of the efficacy of inhaled antibiotics for chronic Pseudomonas infections in cystic fibrosis
- (2012) Kavi J. Littlewood et al. Journal of Cystic Fibrosis
- Airway Epithelial Expression of TLR5 Is Downregulated in Healthy Smokers and Smokers with Chronic Obstructive Pulmonary Disease
- (2012) R. Wang et al. JOURNAL OF IMMUNOLOGY
- Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia
- (2012) Guido Veit et al. MOLECULAR BIOLOGY OF THE CELL
- Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung
- (2012) Alejandro A. Pezzulo et al. NATURE
- A Pharmacologic Approach to Acquired Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction in Smoking Related Lung Disease
- (2012) Peter A. Sloane et al. PLoS One
- CFTR Regulates Early Pathogenesis of Chronic Obstructive Lung Disease in βENaC-Overexpressing Mice
- (2012) Bjarki Johannesson et al. PLoS One
- TACE Activation by MAPK-Mediated Regulation of Cell Surface Dimerization and TIMP3 Association
- (2012) P. Xu et al. Science Signaling
- Targeting F508del-CFTR to develop rational new therapies for cystic fibrosis
- (2011) Zhi-wei Cai et al. ACTA PHARMACOLOGICA SINICA
- Critical role of CFTR-dependent lipid rafts in cigarette smoke-induced lung epithelial injury
- (2011) Manish Bodas et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- The pro- and anti-inflammatory properties of the cytokine interleukin-6
- (2011) Jürgen Scheller et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- IL-6/IL-6 receptor system and its role in physiological and pathological conditions
- (2011) Masahiko Mihara et al. CLINICAL SCIENCE
- Selective blockade of interleukin-6 trans-signaling improves survival in a murine polymicrobial sepsis model*
- (2011) Tanja Barkhausen et al. CRITICAL CARE MEDICINE
- Amphiregulin Exosomes Increase Cancer Cell Invasion
- (2011) James N. Higginbotham et al. CURRENT BIOLOGY
- Initial interrogation, confirmation and fine mapping of modifying genes: STAT3, IL1B and IFNGR1 determine cystic fibrosis disease manifestation
- (2011) Heike Labenski et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Flagellin/TLR5 responses induce mucus hypersecretion by activating EGFR via an epithelial cell signaling cascades
- (2011) Hongmei Yu et al. EXPERIMENTAL CELL RESEARCH
- Hyperviscous airway periciliary and mucous liquid layers in cystic fibrosis measured by confocal fluorescence photobleaching
- (2011) Nico Derichs et al. FASEB JOURNAL
- Cigarette smoke exposure induces CFTR internalization and insolubility, leading to airway surface liquid dehydration
- (2011) Lucy A. Clunes et al. FASEB JOURNAL
- Neuregulin-1-Human Epidermal Receptor-2 Signaling Is a Central Regulator of Pulmonary Epithelial Permeability and Acute Lung Injury
- (2011) James H. Finigan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding
- (2011) Christoph Garbers et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Epidermal Growth Factor (EGF) Ligand Release by Substrate-specific A Disintegrin and Metalloproteases (ADAMs) Involves Different Protein Kinase C (PKC) Isoenzymes Depending on the Stimulus
- (2011) Michelle Dang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mouse models of cystic fibrosis: Phenotypic analysis and research applications
- (2011) Martina Wilke et al. Journal of Cystic Fibrosis
- CCL20/CCR6 Feedback Exaggerates Epidermal Growth Factor Receptor-Dependent MUC5AC Mucin Production in Human Airway Epithelial (NCI-H292) Cells
- (2011) S. Kim et al. JOURNAL OF IMMUNOLOGY
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- (2011) S. Y. Lee et al. JOURNAL OF IMMUNOLOGY
- STAT3 SIGNALING: Anticancer Strategies and Challenges
- (2011) P. A. Johnston et al. MOLECULAR INTERVENTIONS
- Peroxide-dependent sulfenylation of the EGFR catalytic site enhances kinase activity
- (2011) Candice E Paulsen et al. Nature Chemical Biology
- TACE/ADAM-17 Phosphorylation by PKC-Epsilon Mediates Premalignant Changes in Tobacco Smoke-Exposed Lung Cells
- (2011) Hassan Lemjabbar-Alaoui et al. PLoS One
- Progression of early structural lung disease in young children with cystic fibrosis assessed using CT
- (2011) Lauren S Mott et al. THORAX
- Identification of a Novel Mono-Leucine Basolateral Sorting Motif Within the Cytoplasmic Domain of Amphiregulin
- (2011) Jonathan D. Gephart et al. TRAFFIC
- ADAM17: a molecular switch to control inflammation and tissue regeneration
- (2011) Jürgen Scheller et al. TRENDS IN IMMUNOLOGY
- Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17
- (2011) Thorsten Maretzky et al. Nature Communications
- Expression of soluble interleukin-6 receptor in malignant ovarian tissue
- (2010) Kellie S. Rath et al. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Cigarette Smoke Induces Epidermal Growth Factor Receptor-Dependent Redistribution of Apical MUC1 and Junctional β-Catenin in Polarized Human Airway Epithelial Cells
- (2010) Ying-Ting Chen et al. AMERICAN JOURNAL OF PATHOLOGY
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- (2010) David J. Killock et al. BIOCHEMICAL JOURNAL
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- (2010) Sofie H. Willems et al. BIOCHEMICAL JOURNAL
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- (2010) Eamon P. McGreal et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
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- (2010) Jeffery S. Edmiston et al. BIOMARKERS
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- (2010) N. Bles et al. BLOOD
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- (2010) A. Baumgart et al. CANCER RESEARCH
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- (2010) Athena Chalaris et al. EUROPEAN JOURNAL OF CELL BIOLOGY
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- (2010) Andreas Schmid et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2010) Julie Bérubé et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2010) Lai Kuan Goh et al. JOURNAL OF CELL BIOLOGY
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- (2010) S. M. Le Gall et al. JOURNAL OF CELL SCIENCE
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- (2010) Athena Chalaris et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2010) M. Kelly et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
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- (2010) Pinglong Xu et al. MOLECULAR CELL
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- (2010) D. A. Stoltz et al. Science Translational Medicine
- Glutathione dysregulation and the etiology and progression of human diseases
- (2009) Nazzareno Ballatori et al. BIOLOGICAL CHEMISTRY
- IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer
- (2009) Sergei Grivennikov et al. CANCER CELL
- Relationship Between Amphiregulin and Airway Inflammation in Children With Asthma and Eosinophilic Bronchitis
- (2009) Kyung Won Kim et al. CHEST
- Amphiregulin Production by Human Eosinophils
- (2009) Kenji Matsumoto et al. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
- Tissue remodeling induced by hypersecreted epidermal growth factor and amphiregulin in the airway after an acute asthma attack
- (2009) Yukinori Enomoto et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
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- (2009) Agnes W. Boots et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2009) Y. Wang et al. JOURNAL OF IMMUNOLOGY
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- (2009) Isabel M. Carvalho-Oliveira et al. JOURNAL OF PROTEOME RESEARCH
- ADAMs 10 and 17 Represent Differentially Regulated Components of a General Shedding Machinery for Membrane Proteins Such as Transforming Growth Factor α, L-Selectin, and Tumor Necrosis Factor α
- (2009) Sylvain M. Le Gall et al. MOLECULAR BIOLOGY OF THE CELL
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- (2009) Antoon Dijkstra et al. VIRCHOWS ARCHIV
- The Soluble Tumor Necrosis Factor-Alpha Receptor Suppresses Airway Inflammation in a Murine Model of Acute Asthma
- (2009) Hae-Seong Nam et al. YONSEI MEDICAL JOURNAL
- EGF and K+ channel activity control normal and cystic fibrosis bronchial epithelia repair
- (2008) Nguyen Thu Ngan Trinh et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium
- (2008) Jonathan L. Koff et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Rhinovirus-Induced Major Airway Mucin Production Involves a Novel TLR3-EGFR–Dependent Pathway
- (2008) Lingxiang Zhu et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- The Pathology of Chronic Obstructive Pulmonary Disease
- (2008) James C. Hogg et al. Annual Review of Pathology-Mechanisms of Disease
- Clathrin-Mediated Internalization Is Essential for Sustained EGFR Signaling but Dispensable for Degradation
- (2008) Sara Sigismund et al. DEVELOPMENTAL CELL
- Epidermal Growth Factor Receptor Signaling to Erk1/2 and STATs Control the Intensity of the Epithelial Inflammatory Responses to Rhinovirus Infection
- (2008) Kenneth Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Effect of Interleukin-4 and Amphiregulin on the Proliferation of Human Airway Smooth Muscle Cells and Cytokine Release
- (2008) Jung Yeon Shim et al. JOURNAL OF KOREAN MEDICAL SCIENCE
- Structural Determinants of the ADAM Inhibition by TIMP-3: Crystal Structure of the TACE-N-TIMP-3 Complex
- (2008) Magdalena Wisniewska et al. JOURNAL OF MOLECULAR BIOLOGY
- Cystic fibrosis: impaired bicarbonate secretion and mucoviscidosis
- (2008) Paul M Quinton LANCET
- Unknown
- (2008) Minou Adib-Conquy et al. MOLECULAR MEDICINE
- Real-time imaging of the intracellular glutathione redox potential
- (2008) Marcus Gutscher et al. NATURE METHODS
- Superoxide dismutase 1 (SOD1) is essential for H2O2-mediated oxidation and inactivation of phosphatases in growth factor signaling
- (2008) J. C. Juarez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Three-dimensional domain architecture of the ADAM family proteinases
- (2008) Soichi Takeda SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Regulation of the proteolytic disintegrin metalloproteinases, the ‘Sheddases’
- (2008) Gillian Murphy SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
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